SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3h7o'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CBR_A_REAA200_1
(CELLULAR RETINOIC
ACID BINDING PROTEIN
TYPE I)		 3h7o GROUP 3 ALLERGEN
SMIPP-S YV6023A04
(Sarcoptes
scabiei) 		5 / 12 PHE A 212
LEU A 126
ALA A 172
PRO A 209
TYR A 160
 None
 1.17A 1cbrA-3h7oA:
undetectable		 1cbrA-3h7oA:
17.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CBR_B_REAB200_1
(CELLULAR RETINOIC
ACID BINDING PROTEIN
TYPE I)		 3h7o GROUP 3 ALLERGEN
SMIPP-S YV6023A04
(Sarcoptes
scabiei) 		5 / 12 PHE A 212
LEU A 126
ALA A 172
PRO A 209
TYR A 160
 None
 1.17A 1cbrB-3h7oA:
undetectable		 1cbrB-3h7oA:
17.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EIZ_A_SAMA301_0
(FTSJ)		 3h7o GROUP 3 ALLERGEN
SMIPP-S YV6023A04
(Sarcoptes
scabiei) 		5 / 12 ALA A 198
GLY A 131
GLY A  30
GLY A 185
LEU A 143
 None
GOL  A 232 ( 4.0A)
None
None
None
 0.98A 1eizA-3h7oA:
undetectable		 1eizA-3h7oA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EJ0_A_SAMA301_0
(FTSJ)		 3h7o GROUP 3 ALLERGEN
SMIPP-S YV6023A04
(Sarcoptes
scabiei) 		5 / 12 ALA A 198
GLY A 131
GLY A  30
GLY A 185
LEU A 143
 None
GOL  A 232 ( 4.0A)
None
None
None
 0.97A 1ej0A-3h7oA:
undetectable		 1ej0A-3h7oA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 3h7o GROUP 3 ALLERGEN
SMIPP-S YV6023A04
(Sarcoptes
scabiei) 		4 / 5 TYR A  82
ARG A  83
MET A  87
THR A  86
 None
 1.13A 2eimJ-3h7oA:
undetectable		 2eimJ-3h7oA:
12.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 3h7o GROUP 3 ALLERGEN
SMIPP-S YV6023A04
(Sarcoptes
scabiei) 		4 / 5 TYR A  82
ARG A  83
MET A  87
THR A  86
 None
 1.14A 2eimW-3h7oA:
undetectable		 2eimW-3h7oA:
12.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3h7o GROUP 3 ALLERGEN
SMIPP-S YV6023A04
(Sarcoptes
scabiei) 		4 / 7 TYR A  82
ARG A  83
MET A  87
THR A  86
 None
 1.17A 2zxwN-3h7oA:
undetectable
2zxwW-3h7oA:
undetectable		 2zxwN-3h7oA:
16.77
2zxwW-3h7oA:
12.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3h7o GROUP 3 ALLERGEN
SMIPP-S YV6023A04
(Sarcoptes
scabiei) 		4 / 5 TYR A  82
ARG A  83
MET A  87
THR A  86
 None
 1.16A 3abkN-3h7oA:
undetectable
3abkW-3h7oA:
undetectable		 3abkN-3h7oA:
16.77
3abkW-3h7oA:
12.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3h7o GROUP 3 ALLERGEN
SMIPP-S YV6023A04
(Sarcoptes
scabiei) 		4 / 7 TYR A  82
ARG A  83
MET A  87
THR A  86
 None
 1.03A 3ablA-3h7oA:
undetectable
3ablJ-3h7oA:
undetectable		 3ablA-3h7oA:
16.77
3ablJ-3h7oA:
12.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3h7o GROUP 3 ALLERGEN
SMIPP-S YV6023A04
(Sarcoptes
scabiei) 		4 / 6 TYR A  82
ARG A  83
MET A  87
THR A  86
 None
 1.04A 3abmA-3h7oA:
undetectable
3abmJ-3h7oA:
undetectable		 3abmA-3h7oA:
16.77
3abmJ-3h7oA:
12.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1)		 3h7o GROUP 3 ALLERGEN
SMIPP-S YV6023A04
(Sarcoptes
scabiei) 		4 / 5 TYR A  82
ARG A  83
MET A  87
THR A  86
 None
 1.20A 3ag1J-3h7oA:
undetectable		 3ag1J-3h7oA:
12.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1)		 3h7o GROUP 3 ALLERGEN
SMIPP-S YV6023A04
(Sarcoptes
scabiei) 		4 / 5 TYR A  82
ARG A  83
MET A  87
THR A  86
 None
 1.16A 3ag2J-3h7oA:
undetectable		 3ag2J-3h7oA:
12.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1)		 3h7o GROUP 3 ALLERGEN
SMIPP-S YV6023A04
(Sarcoptes
scabiei) 		4 / 5 TYR A  82
ARG A  83
MET A  87
THR A  86
 None
 1.06A 3ag4J-3h7oA:
undetectable		 3ag4J-3h7oA:
12.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D91_A_REMA350_1
(RENIN)		 3h7o GROUP 3 ALLERGEN
SMIPP-S YV6023A04
(Sarcoptes
scabiei) 		5 / 12 GLY A 129
ASP A 186
SER A 181
HIS A  44
ALA A 198
 GOL  A 232 (-3.8A)
GOL  A 232 (-4.4A)
None
None
None
 1.07A 3d91A-3h7oA:
undetectable		 3d91A-3h7oA:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GWX_A_EPAA1_2
(PROTEIN (PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
(PPAR-DELTA)))		 3h7o GROUP 3 ALLERGEN
SMIPP-S YV6023A04
(Sarcoptes
scabiei) 		5 / 12 THR A  15
LEU A 194
ILE A 226
ILE A 222
LEU A 100
 None
 1.32A 3gwxA-3h7oA:
undetectable		 3gwxA-3h7oA:
24.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DX5_B_MIYB1103_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 3h7o GROUP 3 ALLERGEN
SMIPP-S YV6023A04
(Sarcoptes
scabiei) 		5 / 12 SER A 107
ASP A  71
ILE A  56
ALA A  17
VAL A  18
 None
 1.01A 4dx5B-3h7oA:
undetectable		 4dx5B-3h7oA:
11.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U8V_B_MIYB1103_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 3h7o GROUP 3 ALLERGEN
SMIPP-S YV6023A04
(Sarcoptes
scabiei) 		5 / 12 SER A 107
ASP A  71
ILE A  56
ALA A  17
VAL A  18
 None
 0.98A 4u8vB-3h7oA:
undetectable		 4u8vB-3h7oA:
11.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U8Y_B_MIYB1102_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 3h7o GROUP 3 ALLERGEN
SMIPP-S YV6023A04
(Sarcoptes
scabiei) 		5 / 12 SER A 107
ASP A  71
ILE A  56
ALA A  17
VAL A  18
 None
 1.01A 4u8yB-3h7oA:
undetectable		 4u8yB-3h7oA:
11.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U95_B_MIYB1102_1
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 3h7o GROUP 3 ALLERGEN
SMIPP-S YV6023A04
(Sarcoptes
scabiei) 		5 / 12 SER A 107
ASP A  71
ILE A  56
ALA A  17
VAL A  18
 None
 1.02A 4u95B-3h7oA:
undetectable		 4u95B-3h7oA:
11.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZJ8_A_SUVA2001_2
(HUMAN OX1R FUSION
PROTEIN TO P.ABYSII
GLYCOGEN SYNTHASE)		 3h7o GROUP 3 ALLERGEN
SMIPP-S YV6023A04
(Sarcoptes
scabiei) 		4 / 6 TRP A 221
ILE A  91
ILE A  54
VAL A  18
 None
 0.82A 4zj8A-3h7oA:
undetectable		 4zj8A-3h7oA:
18.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZJ8_A_SUVA2001_2
(HUMAN OX1R FUSION
PROTEIN TO P.ABYSII
GLYCOGEN SYNTHASE)		 3h7o GROUP 3 ALLERGEN
SMIPP-S YV6023A04
(Sarcoptes
scabiei) 		4 / 6 TRP A 221
ILE A  91
ILE A  56
VAL A  16
 None
 0.90A 4zj8A-3h7oA:
undetectable		 4zj8A-3h7oA:
18.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_J_CHDJ101_1
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3h7o GROUP 3 ALLERGEN
SMIPP-S YV6023A04
(Sarcoptes
scabiei) 		4 / 5 TYR A  82
ARG A  83
MET A  87
THR A  86
 None
 1.36A 5w97J-3h7oA:
undetectable		 5w97J-3h7oA:
12.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_J_CHDJ101_1
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3h7o GROUP 3 ALLERGEN
SMIPP-S YV6023A04
(Sarcoptes
scabiei) 		4 / 5 TYR A  82
ARG A  83
MET A  87
THR A  86
 None
 1.04A 5wauJ-3h7oA:
undetectable		 5wauJ-3h7oA:
12.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3h7o GROUP 3 ALLERGEN
SMIPP-S YV6023A04
(Sarcoptes
scabiei) 		4 / 5 TYR A  82
ARG A  83
MET A  87
THR A  86
 None
 1.24A 5x1bW-3h7oA:
undetectable		 5x1bW-3h7oA:
12.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3h7o GROUP 3 ALLERGEN
SMIPP-S YV6023A04
(Sarcoptes
scabiei) 		4 / 5 TYR A  82
ARG A  83
MET A  87
THR A  86
 None
 1.25A 5x1fW-3h7oA:
undetectable		 5x1fW-3h7oA:
12.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_J_CHDJ102_0
(CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3h7o GROUP 3 ALLERGEN
SMIPP-S YV6023A04
(Sarcoptes
scabiei) 		4 / 5 TYR A  82
ARG A  83
MET A  87
THR A  86
 None
 1.28A 6nknJ-3h7oA:
undetectable		 6nknJ-3h7oA:
12.12