SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3h7t'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CBR_A_REAA200_1
(CELLULAR RETINOIC
ACID BINDING PROTEIN
TYPE I)		 3h7t GROUP 3 ALLERGEN
SMIPP-S YVT004A06
(Sarcoptes
scabiei) 		5 / 12 PHE A 214
LEU A 121
ALA A 172
PRO A 211
TYR A 156
 None
 1.21A 1cbrA-3h7tA:
undetectable		 1cbrA-3h7tA:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CBR_B_REAB200_1
(CELLULAR RETINOIC
ACID BINDING PROTEIN
TYPE I)		 3h7t GROUP 3 ALLERGEN
SMIPP-S YVT004A06
(Sarcoptes
scabiei) 		5 / 12 PHE A 214
LEU A 121
ALA A 172
PRO A 211
TYR A 156
 None
 1.21A 1cbrB-3h7tA:
undetectable		 1cbrB-3h7tA:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EJ0_A_SAMA301_0
(FTSJ)		 3h7t GROUP 3 ALLERGEN
SMIPP-S YVT004A06
(Sarcoptes
scabiei) 		5 / 12 ALA A 200
GLY A 126
GLY A  27
GLY A 187
LEU A 139
 None
 1.01A 1ej0A-3h7tA:
undetectable		 1ej0A-3h7tA:
22.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EPB_A_9CRA165_2
(EPIDIDYMAL RETINOIC
ACID-BINDING PROTEIN)		 3h7t GROUP 3 ALLERGEN
SMIPP-S YVT004A06
(Sarcoptes
scabiei) 		4 / 7 ALA A 172
PHE A 144
VAL A 146
VAL A 120
 None
 0.87A 1epbA-3h7tA:
undetectable		 1epbA-3h7tA:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_B_SAMB301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 3h7t GROUP 3 ALLERGEN
SMIPP-S YVT004A06
(Sarcoptes
scabiei) 		5 / 12 LYS A   1
GLY A 184
ASP A 185
ALA A 186
ALA A  39
 None
 0.88A 2br4B-3h7tA:
undetectable		 2br4B-3h7tA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_E_SAME301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 3h7t GROUP 3 ALLERGEN
SMIPP-S YVT004A06
(Sarcoptes
scabiei) 		5 / 12 LYS A   1
GLY A 184
ASP A 185
ALA A 186
ALA A  39
 None
 0.87A 2br4E-3h7tA:
undetectable		 2br4E-3h7tA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNJ_A_225A501_1
(CYTOCHROME P450 2C8)		 3h7t GROUP 3 ALLERGEN
SMIPP-S YVT004A06
(Sarcoptes
scabiei) 		5 / 10 ILE A  74
ALA A  40
VAL A  20
PRO A  48
VAL A  18
 None
 1.03A 2nnjA-3h7tA:
undetectable		 2nnjA-3h7tA:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YVL_C_SAMC604_0
(HYPOTHETICAL PROTEIN)		 3h7t GROUP 3 ALLERGEN
SMIPP-S YVT004A06
(Sarcoptes
scabiei) 		5 / 12 ILE A  30
ILE A 105
GLY A  28
ALA A 186
VAL A 122
 None
 1.20A 2yvlC-3h7tA:
undetectable		 2yvlC-3h7tA:
23.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ADS_B_IMNB3_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3h7t GROUP 3 ALLERGEN
SMIPP-S YVT004A06
(Sarcoptes
scabiei) 		5 / 12 GLY A 187
SER A  29
ILE A 105
LEU A 121
VAL A 120
 None
 1.22A 3adsB-3h7tA:
undetectable		 3adsB-3h7tA:
23.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELW_A_SAMA4633_0
(METHYLTRANSFERASE)		 3h7t GROUP 3 ALLERGEN
SMIPP-S YVT004A06
(Sarcoptes
scabiei) 		6 / 12 GLY A 126
GLY A  28
GLY A 187
GLY A 184
THR A  38
VAL A  36
 None
 1.43A 3elwA-3h7tA:
undetectable		 3elwA-3h7tA:
26.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P97_C_SAMC263_0
(NON-STRUCTURAL
PROTEIN 5)		 3h7t GROUP 3 ALLERGEN
SMIPP-S YVT004A06
(Sarcoptes
scabiei) 		6 / 12 GLY A 126
GLY A  28
GLY A 187
GLY A 184
THR A  38
VAL A  36
 None
 1.30A 3p97C-3h7tA:
undetectable		 3p97C-3h7tA:
19.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A79_A_P1BA601_1
(AMINE OXIDASE
[FLAVIN-CONTAINING]
B)		 3h7t GROUP 3 ALLERGEN
SMIPP-S YVT004A06
(Sarcoptes
scabiei) 		5 / 12 LEU A 196
LEU A 215
ILE A  37
TYR A  86
TYR A 166
 None
 1.08A 4a79A-3h7tA:
undetectable		 4a79A-3h7tA:
18.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A79_B_P1BB601_1
(AMINE OXIDASE
[FLAVIN-CONTAINING]
B)		 3h7t GROUP 3 ALLERGEN
SMIPP-S YVT004A06
(Sarcoptes
scabiei) 		5 / 12 LEU A 196
LEU A 215
ILE A  37
TYR A  86
TYR A 166
 None
 1.07A 4a79B-3h7tA:
undetectable		 4a79B-3h7tA:
18.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7A_B_RGZB601_1
(AMINE OXIDASE
[FLAVIN-CONTAINING]
B)		 3h7t GROUP 3 ALLERGEN
SMIPP-S YVT004A06
(Sarcoptes
scabiei) 		5 / 12 LEU A 196
LEU A 215
ILE A  37
TYR A  86
TYR A 166
 None
 1.08A 4a7aB-3h7tA:
undetectable		 4a7aB-3h7tA:
18.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AX8_A_SAMA1474_0
(WBDD)		 3h7t GROUP 3 ALLERGEN
SMIPP-S YVT004A06
(Sarcoptes
scabiei) 		5 / 12 GLY A  28
ALA A  15
ILE A  37
VAL A  18
ILE A  51
 None
 0.88A 4ax8A-3h7tA:
undetectable		 4ax8A-3h7tA:
16.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZV_A_SAMA1474_0
(WBDD)		 3h7t GROUP 3 ALLERGEN
SMIPP-S YVT004A06
(Sarcoptes
scabiei) 		5 / 12 GLY A  28
ALA A  15
ILE A  37
VAL A  18
ILE A  51
 None
 0.89A 4azvA-3h7tA:
undetectable		 4azvA-3h7tA:
16.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTJ_A_SAMA1263_0
(NON-STRUCTURAL
PROTEIN 5)		 3h7t GROUP 3 ALLERGEN
SMIPP-S YVT004A06
(Sarcoptes
scabiei) 		6 / 12 GLY A 126
GLY A  28
GLY A 187
GLY A 184
THR A  38
VAL A  36
 None
 1.28A 4ctjA-3h7tA:
undetectable		 4ctjA-3h7tA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTJ_C_SAMC1263_0
(NON-STRUCTURAL
PROTEIN 5)		 3h7t GROUP 3 ALLERGEN
SMIPP-S YVT004A06
(Sarcoptes
scabiei) 		6 / 12 GLY A 126
GLY A  28
GLY A 187
GLY A 184
THR A  38
VAL A  36
 None
 1.29A 4ctjC-3h7tA:
undetectable		 4ctjC-3h7tA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTK_C_SAMC1263_0
(POLYPROTEIN)		 3h7t GROUP 3 ALLERGEN
SMIPP-S YVT004A06
(Sarcoptes
scabiei) 		6 / 12 GLY A 126
GLY A  28
GLY A 187
GLY A 184
THR A  38
VAL A  36
 None
 1.28A 4ctkC-3h7tA:
undetectable		 4ctkC-3h7tA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_I_ACTI507_0
(RNA POLYMERASE
3D-POL)		 3h7t GROUP 3 ALLERGEN
SMIPP-S YVT004A06
(Sarcoptes
scabiei) 		3 / 3 LYS A  47
PRO A  48
SER A  49
 None
 0.41A 4k50I-3h7tA:
undetectable		 4k50I-3h7tA:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4P3Q_A_FOLA201_0
(DIHYDROFOLATE
REDUCTASE)		 3h7t GROUP 3 ALLERGEN
SMIPP-S YVT004A06
(Sarcoptes
scabiei) 		5 / 12 ILE A 227
THR A  32
LEU A 107
PRO A 108
ILE A 228
 None
 1.06A 4p3qA-3h7tA:
undetectable		 4p3qA-3h7tA:
19.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BMV_C_VLBC507_1
(TUBULIN BETA CHAIN
TUBULIN ALPHA-1B
CHAIN)		 3h7t GROUP 3 ALLERGEN
SMIPP-S YVT004A06
(Sarcoptes
scabiei) 		4 / 6 ASP A 226
TYR A 219
TYR A  86
LEU A 215
 None
 1.37A 5bmvB-3h7tA:
undetectable		 5bmvB-3h7tA:
18.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E9Q_A_SAMA301_0
(GENOME POLYPROTEIN)		 3h7t GROUP 3 ALLERGEN
SMIPP-S YVT004A06
(Sarcoptes
scabiei) 		6 / 12 GLY A 126
GLY A  28
GLY A 187
GLY A 184
THR A  38
VAL A  36
 None
 1.30A 5e9qA-3h7tA:
undetectable		 5e9qA-3h7tA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EC8_C_SAMC4000_0
(GENOME POLYPROTEIN)		 3h7t GROUP 3 ALLERGEN
SMIPP-S YVT004A06
(Sarcoptes
scabiei) 		6 / 12 GLY A 126
GLY A  28
GLY A 187
GLY A 184
THR A  38
VAL A  36
 None
 1.29A 5ec8C-3h7tA:
undetectable		 5ec8C-3h7tA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EHG_C_SAMC4001_0
(RNA-DIRECTED RNA
POLYMERASE NS5)		 3h7t GROUP 3 ALLERGEN
SMIPP-S YVT004A06
(Sarcoptes
scabiei) 		6 / 12 GLY A 126
GLY A  28
GLY A 187
GLY A 184
THR A  38
VAL A  36
 None
 1.29A 5ehgC-3h7tA:
undetectable		 5ehgC-3h7tA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EIF_A_SAMA301_0
(GENOME POLYPROTEIN)		 3h7t GROUP 3 ALLERGEN
SMIPP-S YVT004A06
(Sarcoptes
scabiei) 		6 / 12 GLY A 126
GLY A  28
GLY A 187
GLY A 184
THR A  38
VAL A  36
 None
 1.28A 5eifA-3h7tA:
undetectable		 5eifA-3h7tA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EIF_C_SAMC4000_0
(GENOME POLYPROTEIN)		 3h7t GROUP 3 ALLERGEN
SMIPP-S YVT004A06
(Sarcoptes
scabiei) 		6 / 12 GLY A 126
GLY A  28
GLY A 187
GLY A 184
THR A  38
VAL A  36
 None
 1.28A 5eifC-3h7tA:
undetectable		 5eifC-3h7tA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EIW_C_SAMC4000_0
(NS5
METHYLTRANSFERASE)		 3h7t GROUP 3 ALLERGEN
SMIPP-S YVT004A06
(Sarcoptes
scabiei) 		6 / 12 GLY A 126
GLY A  28
GLY A 187
GLY A 184
THR A  38
VAL A  36
 None
 1.27A 5eiwC-3h7tA:
undetectable		 5eiwC-3h7tA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EKX_B_SAMB4000_0
(NS5
METHYLTRANSFERASE)		 3h7t GROUP 3 ALLERGEN
SMIPP-S YVT004A06
(Sarcoptes
scabiei) 		6 / 12 GLY A 126
GLY A  28
GLY A 187
GLY A 184
THR A  38
VAL A  36
 None
 1.29A 5ekxB-3h7tA:
undetectable		 5ekxB-3h7tA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M5B_A_SAMA1001_0
(NS5
METHYLTRANSFERASE)		 3h7t GROUP 3 ALLERGEN
SMIPP-S YVT004A06
(Sarcoptes
scabiei) 		6 / 12 GLY A 126
GLY A  28
GLY A 187
GLY A 184
THR A  38
VAL A  36
 None
 1.29A 5m5bA-3h7tA:
undetectable		 5m5bA-3h7tA:
19.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NJV_A_SAMA301_0
(NS5)		 3h7t GROUP 3 ALLERGEN
SMIPP-S YVT004A06
(Sarcoptes
scabiei) 		6 / 12 GLY A 126
GLY A  28
GLY A 187
GLY A 184
THR A  38
VAL A  36
 None
 1.29A 5njvA-3h7tA:
undetectable		 5njvA-3h7tA:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NJV_B_SAMB301_0
(NS5)		 3h7t GROUP 3 ALLERGEN
SMIPP-S YVT004A06
(Sarcoptes
scabiei) 		6 / 12 GLY A 126
GLY A  28
GLY A 187
GLY A 184
THR A  38
VAL A  36
 None
 1.30A 5njvB-3h7tA:
undetectable		 5njvB-3h7tA:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U4S_A_BEZA301_0
(PUTATIVE SHORT CHAIN
DEHYDROGENASE)		 3h7t GROUP 3 ALLERGEN
SMIPP-S YVT004A06
(Sarcoptes
scabiei) 		4 / 7 SER A  29
ILE A  30
LEU A 196
PRO A  13
 None
 0.89A 5u4sA-3h7tA:
undetectable		 5u4sA-3h7tA:
17.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VIM_A_SAMA301_0
(METHYLTRANSFERASE)		 3h7t GROUP 3 ALLERGEN
SMIPP-S YVT004A06
(Sarcoptes
scabiei) 		5 / 12 GLY A 126
GLY A  28
GLY A 187
GLY A 184
VAL A  36
 None
 0.96A 5vimA-3h7tA:
undetectable		 5vimA-3h7tA:
20.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CLX_A_SAMA401_0
(O-METHYLTRANSFERASE)		 3h7t GROUP 3 ALLERGEN
SMIPP-S YVT004A06
(Sarcoptes
scabiei) 		5 / 12 ASP A 188
GLY A  17
GLY A  27
SER A  57
VAL A  20
 None
 1.09A 6clxA-3h7tA:
undetectable		 6clxA-3h7tA:
19.34