SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3h7u'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AKD_A_CAMA420_0
(CYTOCHROME P450CAM)		 3h7u ALDO-KETO REDUCTASE
(Arabidopsis
thaliana) 		5 / 11 PHE A  77
THR A  12
THR A  79
VAL A 178
GLY A 156
 None
 1.28A 1akdA-3h7uA:
undetectable		 1akdA-3h7uA:
22.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1S2A_A_IMNA2001_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C3)		 3h7u ALDO-KETO REDUCTASE
(Arabidopsis
thaliana) 		5 / 12 TRP A  83
HIS A 114
GLU A 182
TYR A 206
SER A 207
 None
ACT  A 501 ( 3.8A)
None
NAP  A 401 (-3.2A)
NAP  A 401 (-2.8A)
 0.43A 1s2aA-3h7uA:
41.4		 1s2aA-3h7uA:
40.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1N_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 3h7u ALDO-KETO REDUCTASE
(Arabidopsis
thaliana) 		5 / 11 PHE A  77
THR A  12
THR A  79
VAL A 178
GLY A 156
 None
 1.19A 2a1nA-3h7uA:
undetectable		 2a1nA-3h7uA:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CP4_A_CAMA416_0
(CYTOCHROME P450-CAM)		 3h7u ALDO-KETO REDUCTASE
(Arabidopsis
thaliana) 		5 / 10 PHE A  77
THR A  12
THR A  79
VAL A 178
GLY A 156
 None
 1.23A 2cp4A-3h7uA:
undetectable		 2cp4A-3h7uA:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HDN_L_TACL6888_1
(ELONGATION FACTOR
EF-TU)		 3h7u ALDO-KETO REDUCTASE
(Arabidopsis
thaliana) 		4 / 6 SER A 204
VAL A 181
THR A  79
ASP A  47
 None
None
None
NAP  A 401 (-3.7A)
 1.25A 2hdnJ-3h7uA:
2.1
2hdnK-3h7uA:
undetectable
2hdnL-3h7uA:
2.4		 2hdnJ-3h7uA:
23.58
2hdnK-3h7uA:
9.51
2hdnL-3h7uA:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IEN_B_017B402_1
(PROTEASE)		 3h7u ALDO-KETO REDUCTASE
(Arabidopsis
thaliana) 		5 / 12 LEU A 243
GLY A  20
GLY A  42
ILE A  41
VAL A 269
 None
 0.93A 2ienA-3h7uA:
undetectable		 2ienA-3h7uA:
15.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IEO_A_017A402_1
(PROTEASE)		 3h7u ALDO-KETO REDUCTASE
(Arabidopsis
thaliana) 		5 / 12 LEU A 243
GLY A  20
GLY A  42
ILE A  41
VAL A 269
 None
 0.88A 2ieoA-3h7uA:
undetectable		 2ieoA-3h7uA:
15.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2INE_A_PACA317_0
(ALDOSE REDUCTASE)		 3h7u ALDO-KETO REDUCTASE
(Arabidopsis
thaliana) 		4 / 5 TRP A  24
TYR A  52
HIS A 114
TRP A 115
 ACT  A 501 ( 3.2A)
ACT  A 501 ( 4.4A)
ACT  A 501 ( 3.8A)
NAP  A 401 ( 3.9A)
 0.17A 2ineA-3h7uA:
44.2		 2ineA-3h7uA:
41.95
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2ISF_A_PACA317_0
(ALDOSE REDUCTASE)		 3h7u ALDO-KETO REDUCTASE
(Arabidopsis
thaliana) 		4 / 5 TRP A  24
TYR A  52
HIS A 114
TRP A 115
 ACT  A 501 ( 3.2A)
ACT  A 501 ( 4.4A)
ACT  A 501 ( 3.8A)
NAP  A 401 ( 3.9A)
 0.27A 2isfA-3h7uA:
43.8		 2isfA-3h7uA:
41.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD3_A_CHDA501_0
(FERROCHELATASE)		 3h7u ALDO-KETO REDUCTASE
(Arabidopsis
thaliana) 		5 / 11 LEU A  65
LEU A  62
LEU A 103
THR A  79
VAL A  31
 None
 1.11A 2qd3A-3h7uA:
undetectable		 2qd3A-3h7uA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XRZ_A_ACTA1470_0
(DEOXYRIBODIPYRIMIDIN
E PHOTOLYASE)		 3h7u ALDO-KETO REDUCTASE
(Arabidopsis
thaliana) 		4 / 5 ARG A  98
ALA A  95
ASP A  91
GLU A  94
 None
 1.32A 2xrzA-3h7uA:
undetectable		 2xrzA-3h7uA:
24.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A50_A_VD3A2001_1
(VITAMIN D
HYDROXYLASE)		 3h7u ALDO-KETO REDUCTASE
(Arabidopsis
thaliana) 		5 / 12 PRO A  17
ILE A  46
LEU A  21
ALA A  34
LEU A  65
 None
 1.18A 3a50A-3h7uA:
undetectable		 3a50A-3h7uA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N23_C_OBNC1_1
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 3h7u ALDO-KETO REDUCTASE
(Arabidopsis
thaliana) 		5 / 11 LEU A  76
VAL A  39
ALA A  38
PHE A 267
ARG A 244
 None
 1.30A 3n23C-3h7uA:
undetectable		 3n23C-3h7uA:
17.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3R43_A_ID8A332_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C3)		 3h7u ALDO-KETO REDUCTASE
(Arabidopsis
thaliana) 		5 / 12 TYR A  52
HIS A 114
ASN A 159
TYR A 206
PHE A 295
 ACT  A 501 ( 4.4A)
ACT  A 501 ( 3.8A)
NAP  A 401 (-3.3A)
NAP  A 401 (-3.2A)
None
 1.18A 3r43A-3h7uA:
41.3		 3r43A-3h7uA:
40.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3R43_A_ID8A332_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C3)		 3h7u ALDO-KETO REDUCTASE
(Arabidopsis
thaliana) 		5 / 12 TYR A  52
TRP A  83
HIS A 114
ASN A 159
TYR A 206
 ACT  A 501 ( 4.4A)
None
ACT  A 501 ( 3.8A)
NAP  A 401 (-3.3A)
NAP  A 401 (-3.2A)
 0.28A 3r43A-3h7uA:
41.3		 3r43A-3h7uA:
40.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3R58_A_NPSA332_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C3)		 3h7u ALDO-KETO REDUCTASE
(Arabidopsis
thaliana) 		5 / 10 TYR A  52
HIS A 114
ASN A 159
TYR A 206
PHE A 295
 ACT  A 501 ( 4.4A)
ACT  A 501 ( 3.8A)
NAP  A 401 (-3.3A)
NAP  A 401 (-3.2A)
None
 1.15A 3r58A-3h7uA:
40.9		 3r58A-3h7uA:
40.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3R6I_A_JMSA332_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C3)		 3h7u ALDO-KETO REDUCTASE
(Arabidopsis
thaliana) 		5 / 12 TYR A  52
HIS A 114
ASN A 159
TYR A 206
PHE A 295
 ACT  A 501 ( 4.4A)
ACT  A 501 ( 3.8A)
NAP  A 401 (-3.3A)
NAP  A 401 (-3.2A)
None
 1.18A 3r6iA-3h7uA:
40.9		 3r6iA-3h7uA:
40.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3R6I_A_JMSA332_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C3)		 3h7u ALDO-KETO REDUCTASE
(Arabidopsis
thaliana) 		5 / 12 TYR A  52
TRP A  83
HIS A 114
ASN A 159
TYR A 206
 ACT  A 501 ( 4.4A)
None
ACT  A 501 ( 3.8A)
NAP  A 401 (-3.3A)
NAP  A 401 (-3.2A)
 0.26A 3r6iA-3h7uA:
40.9		 3r6iA-3h7uA:
40.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3R8G_A_IZPA409_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C3)		 3h7u ALDO-KETO REDUCTASE
(Arabidopsis
thaliana) 		5 / 9 TYR A  52
HIS A 114
ASN A 159
TYR A 206
PHE A 295
 ACT  A 501 ( 4.4A)
ACT  A 501 ( 3.8A)
NAP  A 401 (-3.3A)
NAP  A 401 (-3.2A)
None
 1.07A 3r8gA-3h7uA:
40.9		 3r8gA-3h7uA:
40.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3R94_A_FLRA332_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C3)		 3h7u ALDO-KETO REDUCTASE
(Arabidopsis
thaliana) 		5 / 12 TYR A  52
HIS A 114
ASN A 159
TYR A 206
PHE A 295
 ACT  A 501 ( 4.4A)
ACT  A 501 ( 3.8A)
NAP  A 401 (-3.3A)
NAP  A 401 (-3.2A)
None
 1.17A 3r94A-3h7uA:
40.8		 3r94A-3h7uA:
40.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3RX3_A_SUZA317_1
(ALDOSE REDUCTASE)		 3h7u ALDO-KETO REDUCTASE
(Arabidopsis
thaliana) 		5 / 10 TRP A  24
TYR A  52
HIS A 114
PHE A 295
SER A 294
 ACT  A 501 ( 3.2A)
ACT  A 501 ( 4.4A)
ACT  A 501 ( 3.8A)
None
None
 1.04A 3rx3A-3h7uA:
44.4		 3rx3A-3h7uA:
47.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3S3G_A_TLTA317_1
(ALDOSE REDUCTASE)		 3h7u ALDO-KETO REDUCTASE
(Arabidopsis
thaliana) 		4 / 7 TRP A  24
TYR A  52
HIS A 114
PHE A 295
 ACT  A 501 ( 3.2A)
ACT  A 501 ( 4.4A)
ACT  A 501 ( 3.8A)
None
 0.98A 3s3gA-3h7uA:
44.5		 3s3gA-3h7uA:
47.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3S3G_A_TLTA317_1
(ALDOSE REDUCTASE)		 3h7u ALDO-KETO REDUCTASE
(Arabidopsis
thaliana) 		5 / 7 TRP A  24
TYR A  52
HIS A 114
TRP A 115
TRP A 216
 ACT  A 501 ( 3.2A)
ACT  A 501 ( 4.4A)
ACT  A 501 ( 3.8A)
NAP  A 401 ( 3.9A)
None
 1.06A 3s3gA-3h7uA:
44.5		 3s3gA-3h7uA:
47.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TWP_B_SALB404_1
(ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE)		 3h7u ALDO-KETO REDUCTASE
(Arabidopsis
thaliana) 		4 / 7 ASN A  11
ALA A 177
ARG A 153
ALA A  14
 None
 1.12A 3twpB-3h7uA:
undetectable		 3twpB-3h7uA:
23.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3U2C_A_SUZA2001_1
(ALDOSE REDUCTASE)		 3h7u ALDO-KETO REDUCTASE
(Arabidopsis
thaliana) 		5 / 9 TRP A  24
TYR A  52
HIS A 114
TRP A 115
SER A 294
 ACT  A 501 ( 3.2A)
ACT  A 501 ( 4.4A)
ACT  A 501 ( 3.8A)
NAP  A 401 ( 3.9A)
None
 1.16A 3u2cA-3h7uA:
44.5		 3u2cA-3h7uA:
42.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3U2C_A_SUZA2001_1
(ALDOSE REDUCTASE)		 3h7u ALDO-KETO REDUCTASE
(Arabidopsis
thaliana) 		5 / 9 TRP A  24
TYR A  52
HIS A 114
TRP A 115
TRP A 216
 ACT  A 501 ( 3.2A)
ACT  A 501 ( 4.4A)
ACT  A 501 ( 3.8A)
NAP  A 401 ( 3.9A)
None
 1.08A 3u2cA-3h7uA:
44.5		 3u2cA-3h7uA:
42.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UA1_A_08YA600_1
(CYTOCHROME P450 3A4)		 3h7u ALDO-KETO REDUCTASE
(Arabidopsis
thaliana) 		5 / 12 PHE A 160
ILE A  51
THR A 139
PHE A 295
THR A 292
 None
 1.33A 3ua1A-3h7uA:
undetectable		 3ua1A-3h7uA:
23.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UG8_A_IMNA2001_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C3)		 3h7u ALDO-KETO REDUCTASE
(Arabidopsis
thaliana) 		6 / 12 TRP A  83
HIS A 114
ASN A 159
TYR A 206
SER A 207
SER A 211
 None
ACT  A 501 ( 3.8A)
NAP  A 401 (-3.3A)
NAP  A 401 (-3.2A)
NAP  A 401 (-2.8A)
NAP  A 401 (-2.6A)
 0.73A 3ug8A-3h7uA:
40.8		 3ug8A-3h7uA:
40.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UG8_A_IMNA2001_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C3)		 3h7u ALDO-KETO REDUCTASE
(Arabidopsis
thaliana) 		6 / 12 TYR A  52
TRP A  83
HIS A 114
ASN A 159
TYR A 206
SER A 207
 ACT  A 501 ( 4.4A)
None
ACT  A 501 ( 3.8A)
NAP  A 401 (-3.3A)
NAP  A 401 (-3.2A)
NAP  A 401 (-2.8A)
 0.34A 3ug8A-3h7uA:
40.8		 3ug8A-3h7uA:
40.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3UGR_A_IMNA2001_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C3)		 3h7u ALDO-KETO REDUCTASE
(Arabidopsis
thaliana) 		5 / 12 TRP A  83
HIS A 114
TYR A 206
SER A 207
SER A 211
 None
ACT  A 501 ( 3.8A)
NAP  A 401 (-3.2A)
NAP  A 401 (-2.8A)
NAP  A 401 (-2.6A)
 0.75A 3ugrA-3h7uA:
40.4		 3ugrA-3h7uA:
40.28
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3V35_A_NTIA317_1
(ALDOSE REDUCTASE)		 3h7u ALDO-KETO REDUCTASE
(Arabidopsis
thaliana) 		5 / 8 TRP A  24
TRP A  83
HIS A 114
TRP A 115
TRP A 216
 ACT  A 501 ( 3.2A)
None
ACT  A 501 ( 3.8A)
NAP  A 401 ( 3.9A)
None
 1.11A 3v35A-3h7uA:
44.8		 3v35A-3h7uA:
47.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BLV_A_SAMA1281_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE J)		 3h7u ALDO-KETO REDUCTASE
(Arabidopsis
thaliana) 		5 / 12 LEU A 227
HIS A 184
GLY A 246
GLY A 250
GLY A 210
 None
None
None
None
NAP  A 401 (-4.2A)
 1.13A 4blvA-3h7uA:
undetectable		 4blvA-3h7uA:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F4D_A_CHDA504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3h7u ALDO-KETO REDUCTASE
(Arabidopsis
thaliana) 		5 / 12 LEU A  65
LEU A  62
LEU A 103
THR A  79
VAL A  31
 None
 1.18A 4f4dA-3h7uA:
undetectable		 4f4dA-3h7uA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F4D_B_CHDB505_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3h7u ALDO-KETO REDUCTASE
(Arabidopsis
thaliana) 		5 / 12 LEU A  65
LEU A  62
LEU A 103
SER A  80
THR A  79
 None
 1.07A 4f4dB-3h7uA:
undetectable		 4f4dB-3h7uA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F4D_B_CHDB505_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3h7u ALDO-KETO REDUCTASE
(Arabidopsis
thaliana) 		5 / 12 LEU A  65
LEU A 103
SER A  80
THR A  79
VAL A  31
 None
 1.19A 4f4dB-3h7uA:
undetectable		 4f4dB-3h7uA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FP9_D_SAMD401_1
(METHYLTRANSFERASE
NSUN4)		 3h7u ALDO-KETO REDUCTASE
(Arabidopsis
thaliana) 		3 / 3 ASP A 109
ARG A 153
ASP A  75
 None
 0.82A 4fp9D-3h7uA:
undetectable		 4fp9D-3h7uA:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FZV_A_SAMA401_1
(PUTATIVE
METHYLTRANSFERASE
NSUN4)		 3h7u ALDO-KETO REDUCTASE
(Arabidopsis
thaliana) 		3 / 3 ASP A 109
ARG A 153
ASP A  75
 None
 0.83A 4fzvA-3h7uA:
undetectable		 4fzvA-3h7uA:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J6C_A_STRA501_1
(CYTOCHROME P450
MONOOXYGENASE)		 3h7u ALDO-KETO REDUCTASE
(Arabidopsis
thaliana) 		5 / 11 ALA A  34
ALA A  37
ALA A  36
VAL A  71
LEU A  76
 None
 1.09A 4j6cA-3h7uA:
undetectable		 4j6cA-3h7uA:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J6C_B_STRB503_1
(CYTOCHROME P450
MONOOXYGENASE)		 3h7u ALDO-KETO REDUCTASE
(Arabidopsis
thaliana) 		5 / 10 ALA A  34
ALA A  37
ALA A  36
VAL A  71
LEU A  76
 None
 1.10A 4j6cB-3h7uA:
undetectable		 4j6cB-3h7uA:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J6D_A_TESA503_1
(CYTOCHROME P450
MONOOXYGENASE)		 3h7u ALDO-KETO REDUCTASE
(Arabidopsis
thaliana) 		5 / 12 ALA A  34
ALA A  37
ALA A  36
VAL A  71
LEU A  76
 None
 1.06A 4j6dA-3h7uA:
undetectable		 4j6dA-3h7uA:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J6D_B_TESB502_1
(CYTOCHROME P450
MONOOXYGENASE)		 3h7u ALDO-KETO REDUCTASE
(Arabidopsis
thaliana) 		5 / 12 ALA A  34
ALA A  37
ALA A  36
VAL A  71
LEU A  76
 None
 1.07A 4j6dB-3h7uA:
undetectable		 4j6dB-3h7uA:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JBT_A_ASDA501_1
(CYTOCHROME P450
MONOOXYGENASE)		 3h7u ALDO-KETO REDUCTASE
(Arabidopsis
thaliana) 		5 / 12 ALA A  34
ALA A  37
ALA A  36
VAL A  71
LEU A  76
 None
 1.08A 4jbtA-3h7uA:
undetectable		 4jbtA-3h7uA:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JBT_B_ASDB502_1
(CYTOCHROME P450
MONOOXYGENASE)		 3h7u ALDO-KETO REDUCTASE
(Arabidopsis
thaliana) 		5 / 11 ALA A  34
ALA A  37
ALA A  36
VAL A  71
LEU A  76
 None
 1.07A 4jbtB-3h7uA:
undetectable		 4jbtB-3h7uA:
22.10
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4JQ1_B_NPSB401_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 3h7u ALDO-KETO REDUCTASE
(Arabidopsis
thaliana) 		4 / 8 TYR A  52
TRP A  83
HIS A 114
ILE A 126
 ACT  A 501 ( 4.4A)
None
ACT  A 501 ( 3.8A)
None
 0.86A 4jq1B-3h7uA:
41.5		 4jq1B-3h7uA:
40.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4JQ4_B_IMNB401_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 3h7u ALDO-KETO REDUCTASE
(Arabidopsis
thaliana) 		5 / 10 TYR A  52
HIS A 114
ILE A 119
ASN A 159
TYR A 206
 ACT  A 501 ( 4.4A)
ACT  A 501 ( 3.8A)
None
NAP  A 401 (-3.3A)
NAP  A 401 (-3.2A)
 1.12A 4jq4B-3h7uA:
41.2		 4jq4B-3h7uA:
40.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4JQ4_B_IMNB401_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 3h7u ALDO-KETO REDUCTASE
(Arabidopsis
thaliana) 		5 / 10 TYR A  52
HIS A 114
ILE A 126
ASN A 159
TYR A 206
 ACT  A 501 ( 4.4A)
ACT  A 501 ( 3.8A)
None
NAP  A 401 (-3.3A)
NAP  A 401 (-3.2A)
 0.68A 4jq4B-3h7uA:
41.2		 4jq4B-3h7uA:
40.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LG1_B_SAMB301_0
(PROTEIN-LYSINE
METHYLTRANSFERASE
METTL21D)		 3h7u ALDO-KETO REDUCTASE
(Arabidopsis
thaliana) 		5 / 12 ALA A 239
GLY A 210
LEU A 290
ALA A 242
GLU A 286
 NAP  A 401 (-3.3A)
NAP  A 401 (-4.2A)
None
None
None
 1.14A 4lg1B-3h7uA:
undetectable		 4lg1B-3h7uA:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PO0_A_NPSA603_1
(SERUM ALBUMIN)		 3h7u ALDO-KETO REDUCTASE
(Arabidopsis
thaliana) 		6 / 10 LEU A 110
LEU A 112
ASN A 179
VAL A 201
LEU A 165
LEU A 169
 None
 1.35A 4po0A-3h7uA:
undetectable		 4po0A-3h7uA:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R38_C_RBFC201_2
(BLUE-LIGHT-ACTIVATED
HISTIDINE KINASE 2)		 3h7u ALDO-KETO REDUCTASE
(Arabidopsis
thaliana) 		5 / 9 THR A  99
ILE A  51
LEU A 146
VAL A 157
LEU A 112
 None
 1.31A 4r38C-3h7uA:
undetectable		 4r38C-3h7uA:
18.51
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YVP_B_GBMB402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C1)		 3h7u ALDO-KETO REDUCTASE
(Arabidopsis
thaliana) 		5 / 12 TYR A  52
TRP A  83
HIS A 114
ILE A 126
ASN A 159
 ACT  A 501 ( 4.4A)
None
ACT  A 501 ( 3.8A)
None
NAP  A 401 (-3.3A)
 0.66A 4yvpB-3h7uA:
42.0		 4yvpB-3h7uA:
39.55
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YVV_A_GBMA402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C3)		 3h7u ALDO-KETO REDUCTASE
(Arabidopsis
thaliana) 		5 / 9 TYR A  52
TRP A  83
HIS A 114
ASN A 159
TYR A 206
 ACT  A 501 ( 4.4A)
None
ACT  A 501 ( 3.8A)
NAP  A 401 (-3.3A)
NAP  A 401 (-3.2A)
 0.23A 4yvvA-3h7uA:
41.2		 4yvvA-3h7uA:
39.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KB5_A_ADNA401_2
(ADENOSINE KINASE)		 3h7u ALDO-KETO REDUCTASE
(Arabidopsis
thaliana) 		4 / 4 ASN A 228
LEU A 227
SER A 237
LEU A 209
 None
None
NAP  A 401 ( 4.8A)
NAP  A 401 (-3.8A)
 1.29A 5kb5A-3h7uA:
undetectable		 5kb5A-3h7uA:
25.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZVG_A_SAMA401_1
(389AA LONG
HYPOTHETICAL
NUCLEOLAR PROTEIN)		 3h7u ALDO-KETO REDUCTASE
(Arabidopsis
thaliana) 		3 / 3 ASP A 109
ARG A 153
ASP A  75
 None
 0.74A 5zvgA-3h7uA:
undetectable		 5zvgA-3h7uA:
22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZVG_B_SAMB401_1
(389AA LONG
HYPOTHETICAL
NUCLEOLAR PROTEIN)		 3h7u ALDO-KETO REDUCTASE
(Arabidopsis
thaliana) 		3 / 3 ASP A 109
ARG A 153
ASP A  75
 None
 0.73A 5zvgB-3h7uA:
undetectable		 5zvgB-3h7uA:
22.22