SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3h84'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_J_TRPJ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3h84 ATPASE GET3
(Saccharomyces
cerevisiae) 		4 / 8 THR A 173
SER A 141
THR A  56
ILE A  54
 None
None
NA  A 358 (-4.0A)
None
 0.75A 1c9sI-3h84A:
undetectable
1c9sJ-3h84A:
undetectable		 1c9sI-3h84A:
12.99
1c9sJ-3h84A:
12.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_A_TRPA81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3h84 ATPASE GET3
(Saccharomyces
cerevisiae) 		4 / 7 THR A  56
ILE A  54
THR A 173
SER A 141
 NA  A 358 (-4.0A)
None
None
None
 0.77A 1gtnA-3h84A:
undetectable
1gtnK-3h84A:
undetectable		 1gtnA-3h84A:
12.99
1gtnK-3h84A:
12.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_B_TRPB81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3h84 ATPASE GET3
(Saccharomyces
cerevisiae) 		4 / 8 THR A 173
SER A 141
THR A  56
ILE A  54
 None
None
NA  A 358 (-4.0A)
None
 0.79A 1gtnA-3h84A:
undetectable
1gtnB-3h84A:
undetectable		 1gtnA-3h84A:
12.99
1gtnB-3h84A:
12.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_E_TRPE81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3h84 ATPASE GET3
(Saccharomyces
cerevisiae) 		4 / 6 THR A 173
SER A 141
THR A  56
ILE A  54
 None
None
NA  A 358 (-4.0A)
None
 0.80A 1gtnD-3h84A:
undetectable
1gtnE-3h84A:
undetectable		 1gtnD-3h84A:
12.99
1gtnE-3h84A:
12.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_K_TRPK81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3h84 ATPASE GET3
(Saccharomyces
cerevisiae) 		4 / 7 THR A 173
SER A 141
THR A  56
ILE A  54
 None
None
NA  A 358 (-4.0A)
None
 0.78A 1gtnJ-3h84A:
undetectable
1gtnK-3h84A:
undetectable		 1gtnJ-3h84A:
12.99
1gtnK-3h84A:
12.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_P_TRPP81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 3h84 ATPASE GET3
(Saccharomyces
cerevisiae) 		4 / 8 THR A  56
ILE A  54
THR A 173
SER A 141
 NA  A 358 (-4.0A)
None
None
None
 0.81A 1gtnP-3h84A:
undetectable
1gtnQ-3h84A:
undetectable		 1gtnP-3h84A:
12.99
1gtnQ-3h84A:
12.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JIP_A_KTNA801_1
(CYTOCHROME P450
107A1)		 3h84 ATPASE GET3
(Saccharomyces
cerevisiae) 		5 / 12 ALA A 139
GLY A 131
LEU A 120
ALA A 125
LEU A 219
 None
 1.32A 1jipA-3h84A:
undetectable		 1jipA-3h84A:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_B_TRPB81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3h84 ATPASE GET3
(Saccharomyces
cerevisiae) 		4 / 8 THR A  56
ILE A  54
THR A 173
SER A 141
 NA  A 358 (-4.0A)
None
None
None
 0.78A 1utdB-3h84A:
undetectable
1utdC-3h84A:
undetectable		 1utdB-3h84A:
12.99
1utdC-3h84A:
12.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_F_TRPF81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 3h84 ATPASE GET3
(Saccharomyces
cerevisiae) 		4 / 8 THR A  56
ILE A  54
THR A 173
SER A 141
 NA  A 358 (-4.0A)
None
None
None
 0.78A 1utdF-3h84A:
undetectable
1utdG-3h84A:
undetectable		 1utdF-3h84A:
12.99
1utdG-3h84A:
12.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V8B_A_ADNA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 3h84 ATPASE GET3
(Saccharomyces
cerevisiae) 		3 / 3 GLU A  68
GLU A  87
LEU A  52
 None
 0.73A 1v8bA-3h84A:
undetectable		 1v8bA-3h84A:
23.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BEX_C_PAUC248_0
(TYPE III
PANTOTHENATE KINASE)		 3h84 ATPASE GET3
(Saccharomyces
cerevisiae) 		5 / 11 ASN A  82
GLY A  79
ILE A  40
LEU A  44
THR A 328
 None
 1.41A 3bexC-3h84A:
undetectable
3bexD-3h84A:
undetectable		 3bexC-3h84A:
20.97
3bexD-3h84A:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BEX_D_PAUD248_0
(TYPE III
PANTOTHENATE KINASE)		 3h84 ATPASE GET3
(Saccharomyces
cerevisiae) 		5 / 10 LEU A  44
THR A 328
ASN A  82
GLY A  79
ILE A  40
 None
 1.40A 3bexC-3h84A:
undetectable
3bexD-3h84A:
1.2		 3bexC-3h84A:
20.97
3bexD-3h84A:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BEX_E_PAUE248_0
(TYPE III
PANTOTHENATE KINASE)		 3h84 ATPASE GET3
(Saccharomyces
cerevisiae) 		5 / 10 ASN A  82
GLY A  79
ILE A  40
LEU A  44
THR A 328
 None
 1.41A 3bexE-3h84A:
undetectable
3bexF-3h84A:
undetectable		 3bexE-3h84A:
20.97
3bexF-3h84A:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BEX_F_PAUF248_0
(TYPE III
PANTOTHENATE KINASE)		 3h84 ATPASE GET3
(Saccharomyces
cerevisiae) 		5 / 11 LEU A  44
THR A 328
ASN A  82
GLY A  79
ILE A  40
 None
 1.40A 3bexE-3h84A:
undetectable
3bexF-3h84A:
undetectable		 3bexE-3h84A:
20.97
3bexF-3h84A:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_C_PAUC248_0
(TYPE III
PANTOTHENATE KINASE)		 3h84 ATPASE GET3
(Saccharomyces
cerevisiae) 		5 / 11 ASN A  82
GLY A  79
ILE A  40
LEU A  44
THR A 328
 None
 1.42A 3bf1C-3h84A:
undetectable
3bf1D-3h84A:
undetectable		 3bf1C-3h84A:
20.97
3bf1D-3h84A:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BF1_D_PAUD248_0
(TYPE III
PANTOTHENATE KINASE)		 3h84 ATPASE GET3
(Saccharomyces
cerevisiae) 		5 / 11 LEU A  44
THR A 328
ASN A  82
GLY A  79
ILE A  40
 None
 1.42A 3bf1C-3h84A:
undetectable
3bf1D-3h84A:
undetectable		 3bf1C-3h84A:
20.97
3bf1D-3h84A:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CD2_A_MTXA307_1
(DIHYDROFOLATE
REDUCTASE)		 3h84 ATPASE GET3
(Saccharomyces
cerevisiae) 		5 / 12 ILE A 136
ILE A 212
PHE A 190
LEU A 186
ILE A 133
 None
 1.08A 3cd2A-3h84A:
3.4		 3cd2A-3h84A:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G2O_A_SAMA500_1
(PCZA361.24)		 3h84 ATPASE GET3
(Saccharomyces
cerevisiae) 		3 / 3 ARG A 322
GLU A  87
ASP A  89
 None
 0.76A 3g2oA-3h84A:
undetectable		 3g2oA-3h84A:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R55_A_PZAA598_0
(LACTOPEROXIDASE)		 3h84 ATPASE GET3
(Saccharomyces
cerevisiae) 		3 / 3 GLU A 153
PHE A 160
GLN A 152
 None
 0.98A 3r55A-3h84A:
undetectable		 3r55A-3h84A:
21.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NED_A_PFNA709_1
(LACTOTRANSFERRIN)		 3h84 ATPASE GET3
(Saccharomyces
cerevisiae) 		4 / 6 VAL A  23
ASP A 166
ALA A  65
PHE A  66
 None
 1.17A 4nedA-3h84A:
undetectable		 4nedA-3h84A:
18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDN_N_EVPN2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 3h84 ATPASE GET3
(Saccharomyces
cerevisiae) 		4 / 6 SER A  55
GLY A 323
ARG A 322
GLY A  67
 None
 0.83A 5cdnR-3h84A:
undetectable
5cdnS-3h84A:
undetectable		 5cdnR-3h84A:
22.42
5cdnS-3h84A:
21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDP_H_EVPH2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B)		 3h84 ATPASE GET3
(Saccharomyces
cerevisiae) 		4 / 6 SER A  55
GLY A 323
ARG A 322
GLY A  67
 None
 0.88A 5cdpA-3h84A:
undetectable
5cdpB-3h84A:
undetectable		 5cdpA-3h84A:
23.08
5cdpB-3h84A:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_H_SAMH301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))		 3h84 ATPASE GET3
(Saccharomyces
cerevisiae) 		5 / 12 ASP A 128
ALA A 127
THR A 182
GLN A 178
GLY A 135
 None
 1.29A 5hfjH-3h84A:
undetectable		 5hfjH-3h84A:
19.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW8_G_FK5G201_1
(FK506-BINDING
PROTEIN 1)		 3h84 ATPASE GET3
(Saccharomyces
cerevisiae) 		3 / 3 ILE A 133
PRO A 134
ILE A 136
 None
 0.36A 5hw8F-3h84A:
undetectable		 5hw8F-3h84A:
15.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XXI_A_LSNA503_1
(CYTOCHROME P450 2C9)		 3h84 ATPASE GET3
(Saccharomyces
cerevisiae) 		5 / 12 ILE A 347
PHE A 333
GLN A  41
LEU A 324
LEU A 350
 None
 1.22A 5xxiA-3h84A:
undetectable		 5xxiA-3h84A:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7U_A_FVTA501_0
(PEPTIDE ABC
TRANSPORTER PERMEASE)		 3h84 ATPASE GET3
(Saccharomyces
cerevisiae) 		4 / 6 ASN A 339
ASN A 279
PRO A 340
ILE A 341
 None
 1.17A 6h7uA-3h84A:
undetectable		 6h7uA-3h84A:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HZP_A_FVTA501_0
(PEPTIDE ABC
TRANSPORTER PERMEASE)		 3h84 ATPASE GET3
(Saccharomyces
cerevisiae) 		4 / 8 ASN A 339
ASN A 279
PRO A 340
ILE A 341
 None
 1.08A 6hzpA-3h84A:
undetectable		 6hzpA-3h84A:
21.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6IBL_B_H98B501_0
(THIOREDOXIN 1,BETA-1
ADRENERGIC RECEPTOR)		 3h84 ATPASE GET3
(Saccharomyces
cerevisiae) 		5 / 12 THR A  56
VAL A 145
PHE A  22
PHE A 230
VAL A  23
 NA  A 358 (-4.0A)
None
None
None
None
 1.43A 6iblB-3h84A:
undetectable		 6iblB-3h84A:
22.60