SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3h86'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1GTN_O_TRPO81_0 (TRP RNA-BINDING ATTENUATION PROTEIN)	3h86	ADENYLATE KINASE (Methanococcus maripaludis)	5 / 10	GLY B 10 HIS B 151 ALA B 159 THR B 9 ALA B 158	None	1.42A	1gtnO-3h86B: undetectable 1gtnP-3h86B: undetectable	1gtnO-3h86B: 18.65 1gtnP-3h86B: 18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1GTN_Q_TRPQ81_0 (TRP RNA-BINDING ATTENUATION PROTEIN)	3h86	ADENYLATE KINASE (Methanococcus maripaludis)	5 / 9	GLY B 10 HIS B 151 ALA B 159 THR B 9 ALA B 158	None	1.41A	1gtnQ-3h86B: undetectable 1gtnR-3h86B: undetectable	1gtnQ-3h86B: 18.65 1gtnR-3h86B: 18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1WOP_A_FFOA2887_1 (AMINOMETHYLTRANSFERA SE)	3h86	ADENYLATE KINASE (Methanococcus maripaludis)	3 / 3	ASP B 181 GLU B 29 ARG B 192	None	0.82A	1wopA-3h86B: undetectable	1wopA-3h86B: 20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4Y8W_C_STRC603_2 (CYTOCHROME P450 21-HYDROXYLASE)	3h86	ADENYLATE KINASE (Methanococcus maripaludis)	3 / 3	LEU B 110 VAL B 5 ASP B 116	None	0.68A	4y8wC-3h86B: undetectable	4y8wC-3h86B: 20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EB5_A_010A609_0 (HNL ISOENZYME 5)	3h86	ADENYLATE KINASE (Methanococcus maripaludis)	5 / 11	ALA B 74 ALA B 42 VAL B 37 LEU B 105 VAL B 89	None	1.22A	5eb5A-3h86B: undetectable	5eb5A-3h86B: 17.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EB5_B_010B607_0 (HNL ISOENZYME 5)	3h86	ADENYLATE KINASE (Methanococcus maripaludis)	5 / 10	ALA B 74 ALA B 42 VAL B 37 LEU B 105 VAL B 89	None	1.23A	5eb5B-3h86B: undetectable	5eb5B-3h86B: 17.37

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1GTN_O_TRPO81_0","TRP RNA-BINDING ATTENUATION PROTEIN","3h86","ADENYLATE KINASE","Methanococcus maripaludis",5,"GLY B  10;HIS B 151;ALA B 159;THR B   9;ALA B 158","None","1.42A","1gtnO-3h86B:undetectable;1gtnP-3h86B:undetectable","1gtnO-3h86B:18.65;1gtnP-3h86B:18.65"],["1GTN_Q_TRPQ81_0","TRP RNA-BINDING ATTENUATION PROTEIN","3h86","ADENYLATE KINASE","Methanococcus maripaludis",5,"GLY B  10;HIS B 151;ALA B 159;THR B   9;ALA B 158","None","1.41A","1gtnQ-3h86B:undetectable;1gtnR-3h86B:undetectable","1gtnQ-3h86B:18.65;1gtnR-3h86B:18.65"],["1WOP_A_FFOA2887_1","AMINOMETHYLTRANSFERASE","3h86","ADENYLATE KINASE","Methanococcus maripaludis",3,"ASP B 181;GLU B  29;ARG B 192","None","0.82A","1wopA-3h86B:undetectable","1wopA-3h86B:20.87"],["4Y8W_C_STRC603_2","CYTOCHROME P450 21-HYDROXYLASE","3h86","ADENYLATE KINASE","Methanococcus maripaludis",3,"LEU B 110;VAL B   5;ASP B 116","None","0.68A","4y8wC-3h86B:undetectable","4y8wC-3h86B:20.19"],["5EB5_A_010A609_0","HNL ISOENZYME 5","3h86","ADENYLATE KINASE","Methanococcus maripaludis",5,"ALA B  74;ALA B  42;VAL B  37;LEU B 105;VAL B  89","None","1.22A","5eb5A-3h86B:undetectable","5eb5A-3h86B:17.37"],["5EB5_B_010B607_0","HNL ISOENZYME 5","3h86","ADENYLATE KINASE","Methanococcus maripaludis",5,"ALA B  74;ALA B  42;VAL B  37;LEU B 105;VAL B  89","None","1.23A","5eb5B-3h86B:undetectable","5eb5B-3h86B:17.37"]]