SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3h87'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TT6_B_DESB128_1
(TRANSTHYRETIN)		 3h87 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Mycobacterium
tuberculosis) 		4 / 5 LEU C  24
ALA C  22
LEU C  26
SER C  27
 GOL  C  74 (-4.3A)
None
None
None
 1.03A 1tt6B-3h87C:
undetectable		 1tt6B-3h87C:
23.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_F_SC2F1291_1
(FICOLIN-2)		 3h87 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Mycobacterium
tuberculosis) 		4 / 6 SER A  11
ASP A   9
ASP A 117
GLU A  43
 None
None
MG  A 159 (-2.6A)
None
 1.12A 2j2pE-3h87A:
undetectable
2j2pF-3h87A:
undetectable		 2j2pE-3h87A:
20.09
2j2pF-3h87A:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PIW_A_T3A932_1
(ANDROGEN RECEPTOR)		 3h87 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Mycobacterium
tuberculosis) 		4 / 6 LEU C  17
VAL C  13
ILE C   9
ILE C  32
 None
 0.90A 2piwA-3h87C:
undetectable		 2piwA-3h87C:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DOU_A_SAMA1_1
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE J)		 3h87 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Mycobacterium
tuberculosis) 		3 / 3 ASP C  11
ASP C  18
ASP C   8
 None
 0.74A 3douA-3h87C:
undetectable		 3douA-3h87C:
18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4I89_A_1FLA201_1
(TRANSTHYRETIN)		 3h87 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Mycobacterium
tuberculosis) 		4 / 6 LEU C  24
ALA C  22
LEU C  26
SER C  27
 GOL  C  74 (-4.3A)
None
None
None
 1.02A 4i89A-3h87C:
undetectable		 4i89A-3h87C:
23.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PWJ_A_30ZA201_1
(TRANSTHYRETIN)		 3h87 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Mycobacterium
tuberculosis) 		4 / 6 LEU C  24
ALA C  22
LEU C  26
SER C  27
 GOL  C  74 (-4.3A)
None
None
None
 1.04A 4pwjA-3h87C:
undetectable		 4pwjA-3h87C:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZE2_A_1YNA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3h87 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Mycobacterium
tuberculosis) 		5 / 12 GLY A  32
ILE A  53
PHE A  58
GLY A  45
LEU A  13
 None
 1.17A 4ze2A-3h87A:
undetectable		 4ze2A-3h87A:
14.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXD_A_RBVA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 3h87 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Mycobacterium
tuberculosis) 		3 / 3 THR A 131
HIS A  92
LEU A 100
 None
 0.62A 5axdA-3h87A:
undetectable		 5axdA-3h87A:
15.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXD_C_RBVC502_2
(ADENOSYLHOMOCYSTEINA
SE)		 3h87 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Mycobacterium
tuberculosis) 		3 / 3 THR A 131
HIS A  92
LEU A 100
 None
 0.59A 5axdC-3h87A:
undetectable		 5axdC-3h87A:
15.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BOJ_A_4TXA201_1
(TRANSTHYRETIN)		 3h87 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Mycobacterium
tuberculosis) 		4 / 6 LEU C  24
ALA C  22
LEU C  26
SER C  27
 GOL  C  74 (-4.3A)
None
None
None
 1.03A 5bojA-3h87C:
undetectable		 5bojA-3h87C:
23.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5L4I_A_6J3A201_0
(TRANSTHYRETIN)		 3h87 PUTATIVE
UNCHARACTERIZED
PROTEIN
(Mycobacterium
tuberculosis) 		4 / 6 LEU C  24
ALA C  22
LEU C  26
SER C  27
 GOL  C  74 (-4.3A)
None
None
None
 1.00A 5l4iA-3h87C:
undetectable		 5l4iA-3h87C:
23.64