SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3h8l'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM4_A_DXCA1002_0
(MAJOR POLLEN
ALLERGEN BET V 1-L)		 3h8l NADH OXIDASE
(Acidianus
ambivalens) 		5 / 12 ILE A 261
TYR A 192
VAL A 204
ILE A 233
TYR A 228
 None
 1.27A 1fm4A-3h8lA:
undetectable		 1fm4A-3h8lA:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM4_A_DXCA1002_0
(MAJOR POLLEN
ALLERGEN BET V 1-L)		 3h8l NADH OXIDASE
(Acidianus
ambivalens) 		5 / 12 ILE A 263
TYR A 192
VAL A 204
ILE A 233
LEU A  45
 None
 1.12A 1fm4A-3h8lA:
undetectable		 1fm4A-3h8lA:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GAH_A_ACRA497_2
(GLUCOAMYLASE-471)		 3h8l NADH OXIDASE
(Acidianus
ambivalens) 		4 / 6 ALA A  16
SER A 310
ARG A 334
LEU A  20
 None
 1.10A 1gahA-3h8lA:
undetectable		 1gahA-3h8lA:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JLB_A_NVPA999_1
(HIV-1 RT A-CHAIN)		 3h8l NADH OXIDASE
(Acidianus
ambivalens) 		4 / 8 LEU A 141
VAL A 202
GLY A 146
LEU A 189
 None
 0.70A 1jlbA-3h8lA:
undetectable		 1jlbA-3h8lA:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BM9_D_SAMD301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 3h8l NADH OXIDASE
(Acidianus
ambivalens) 		5 / 12 LEU A 316
GLU A 179
GLY A 180
SER A 176
ALA A 352
 FAD  A1001 ( 4.0A)
None
S3H  A1002 ( 4.3A)
None
None
 1.17A 2bm9D-3h8lA:
3.2		 2bm9D-3h8lA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C49_A_ADNA1301_1
(SUGAR KINASE MJ0406)		 3h8l NADH OXIDASE
(Acidianus
ambivalens) 		5 / 12 ALA A  13
GLY A   9
GLY A   8
ASN A  34
ALA A  17
 None
FAD  A1001 (-3.4A)
FAD  A1001 (-3.4A)
FAD  A1001 (-3.3A)
None
 1.10A 2c49A-3h8lA:
5.3		 2c49A-3h8lA:
23.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJ3_A_GBNA2414_1
(BRANCHED-CHAIN AMINO
ACID
AMINOTRANSFERASE)		 3h8l NADH OXIDASE
(Acidianus
ambivalens) 		4 / 8 GLY A   8
THR A  15
ALA A  16
ALA A  17
 FAD  A1001 (-3.4A)
None
None
None
 0.53A 2ej3A-3h8lA:
undetectable		 2ej3A-3h8lA:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OKC_A_SAMA500_0
(TYPE I RESTRICTION
ENZYME STYSJI M
PROTEIN)		 3h8l NADH OXIDASE
(Acidianus
ambivalens) 		5 / 12 TYR A 268
ALA A 174
GLY A 159
SER A 214
PRO A 314
 None
 1.12A 2okcA-3h8lA:
2.9		 2okcA-3h8lA:
24.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OKC_B_SAMB500_0
(TYPE I RESTRICTION
ENZYME STYSJI M
PROTEIN)		 3h8l NADH OXIDASE
(Acidianus
ambivalens) 		5 / 12 TYR A 268
ALA A 174
GLY A 159
SER A 214
PRO A 314
 None
 1.11A 2okcB-3h8lA:
3.0		 2okcB-3h8lA:
24.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD4_A_CHDA801_0
(FERROCHELATASE)		 3h8l NADH OXIDASE
(Acidianus
ambivalens) 		5 / 12 LEU A 113
ARG A  10
SER A 153
PRO A 181
VAL A 182
 None
FAD  A1001 (-4.0A)
None
FAD  A1001 (-4.4A)
None
 1.16A 2qd4A-3h8lA:
undetectable		 2qd4A-3h8lA:
22.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HBB_B_TMQB612_1
(DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 3h8l NADH OXIDASE
(Acidianus
ambivalens) 		5 / 9 VAL A 204
ALA A 259
ILE A 244
PHE A 133
ILE A 151
 None
 1.14A 3hbbB-3h8lA:
undetectable		 3hbbB-3h8lA:
22.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUE_D_SUED1201_2
(NS3 PROTEASE, NS4A
PROTEIN)		 3h8l NADH OXIDASE
(Acidianus
ambivalens) 		3 / 3 TYR A 192
LEU A 235
LYS A 234
 None
 0.75A 3sueD-3h8lA:
undetectable		 3sueD-3h8lA:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_A_SAMA501_1
(MNMC2)		 3h8l NADH OXIDASE
(Acidianus
ambivalens) 		4 / 6 HIS A 330
ASP A 283
ASP A 291
ASN A 309
 None
 1.34A 3vywA-3h8lA:
undetectable		 3vywA-3h8lA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A84_A_DXCA1160_0
(MAJOR POLLEN
ALLERGEN BET V 1-A)		 3h8l NADH OXIDASE
(Acidianus
ambivalens) 		5 / 12 ILE A 263
TYR A 192
VAL A 204
ILE A 233
LEU A  45
 None
 1.08A 4a84A-3h8lA:
undetectable		 4a84A-3h8lA:
16.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TXN_A_URFA302_1
(URIDINE
PHOSPHORYLASE)		 3h8l NADH OXIDASE
(Acidianus
ambivalens) 		4 / 7 THR A 262
GLY A 152
ALA A 150
ILE A 257
 None
 0.95A 4txnA-3h8lA:
undetectable		 4txnA-3h8lA:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TXN_B_URFB302_1
(URIDINE
PHOSPHORYLASE)		 3h8l NADH OXIDASE
(Acidianus
ambivalens) 		4 / 7 THR A 262
GLY A 152
ALA A 150
ILE A 257
 None
 0.92A 4txnB-3h8lA:
undetectable		 4txnB-3h8lA:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TXN_C_URFC302_1
(URIDINE
PHOSPHORYLASE)		 3h8l NADH OXIDASE
(Acidianus
ambivalens) 		4 / 7 THR A 262
GLY A 152
ALA A 150
ILE A 257
 None
 0.96A 4txnC-3h8lA:
undetectable		 4txnC-3h8lA:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TXN_D_URFD302_1
(URIDINE
PHOSPHORYLASE)		 3h8l NADH OXIDASE
(Acidianus
ambivalens) 		4 / 7 THR A 262
GLY A 152
ALA A 150
ILE A 257
 None
 0.95A 4txnD-3h8lA:
undetectable		 4txnD-3h8lA:
22.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XP9_C_1WEC706_1
(TRANSPORTER)		 3h8l NADH OXIDASE
(Acidianus
ambivalens) 		4 / 4 PHE A 287
ASP A 283
GLY A 270
SER A 310
 None
 1.18A 4xp9C-3h8lA:
undetectable		 4xp9C-3h8lA:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDN_G_EVPG2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 3h8l NADH OXIDASE
(Acidianus
ambivalens) 		4 / 6 GLU A  75
GLY A 306
ASP A 307
GLY A  12
 PO4  A2001 (-2.5A)
FAD  A1001 (-3.2A)
FAD  A1001 (-3.2A)
FAD  A1001 (-3.8A)
 0.76A 5cdnA-3h8lA:
undetectable
5cdnB-3h8lA:
2.3		 5cdnA-3h8lA:
21.57
5cdnB-3h8lA:
18.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDN_N_EVPN2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 3h8l NADH OXIDASE
(Acidianus
ambivalens) 		4 / 6 GLU A  75
GLY A 306
ASP A 307
GLY A  12
 PO4  A2001 (-2.5A)
FAD  A1001 (-3.2A)
FAD  A1001 (-3.2A)
FAD  A1001 (-3.8A)
 0.77A 5cdnR-3h8lA:
undetectable
5cdnS-3h8lA:
undetectable		 5cdnR-3h8lA:
21.57
5cdnS-3h8lA:
18.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDN_O_EVPO2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 3h8l NADH OXIDASE
(Acidianus
ambivalens) 		4 / 6 GLU A  75
GLY A 306
ASP A 307
GLY A  12
 PO4  A2001 (-2.5A)
FAD  A1001 (-3.2A)
FAD  A1001 (-3.2A)
FAD  A1001 (-3.8A)
 0.77A 5cdnC-3h8lA:
undetectable
5cdnD-3h8lA:
undetectable		 5cdnC-3h8lA:
21.57
5cdnD-3h8lA:
18.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDN_P_EVPP2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 3h8l NADH OXIDASE
(Acidianus
ambivalens) 		4 / 6 GLU A  75
GLY A 306
ASP A 307
GLY A  12
 PO4  A2001 (-2.5A)
FAD  A1001 (-3.2A)
FAD  A1001 (-3.2A)
FAD  A1001 (-3.8A)
 0.77A 5cdnT-3h8lA:
undetectable
5cdnU-3h8lA:
2.3		 5cdnT-3h8lA:
21.57
5cdnU-3h8lA:
18.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DPD_B_SAMB601_0
(PROTEIN LYSINE
METHYLTRANSFERASE 1)		 3h8l NADH OXIDASE
(Acidianus
ambivalens) 		5 / 12 TYR A 344
GLY A 324
LEU A  14
VAL A 305
VAL A   6
 None
 1.16A 5dpdB-3h8lA:
2.7		 5dpdB-3h8lA:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E4D_B_BEZB203_0
(HYDROXYNITRILE LYASE)		 3h8l NADH OXIDASE
(Acidianus
ambivalens) 		4 / 4 VAL A 204
ALA A 259
ILE A 263
THR A 262
 None
 1.17A 5e4dB-3h8lA:
undetectable		 5e4dB-3h8lA:
19.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_B_6K9B503_0
(TUBULIN BETA-2B
CHAIN)		 3h8l NADH OXIDASE
(Acidianus
ambivalens) 		5 / 11 VAL A  88
THR A 278
TYR A  90
TYR A 102
LEU A   5
 None
 1.29A 5jh7B-3h8lA:
2.3		 5jh7B-3h8lA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JH7_D_6K9D502_0
(TUBULIN BETA-2B
CHAIN)		 3h8l NADH OXIDASE
(Acidianus
ambivalens) 		5 / 11 VAL A  88
THR A 278
TYR A  90
TYR A 102
LEU A   5
 None
 1.29A 5jh7D-3h8lA:
2.3		 5jh7D-3h8lA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VW9_A_NCAA403_0
(FERREDOXIN--NADP
REDUCTASE)		 3h8l NADH OXIDASE
(Acidianus
ambivalens) 		4 / 8 THR A 323
GLY A 324
ALA A 327
GLY A  12
 None
None
None
FAD  A1001 (-3.8A)
 0.57A 5vw9A-3h8lA:
3.6		 5vw9A-3h8lA:
21.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CDU_E_EY4E500_0
(CHIMERIC ALPHA1GABAA
RECEPTOR)		 3h8l NADH OXIDASE
(Acidianus
ambivalens) 		4 / 8 ILE A 109
ALA A  16
THR A  15
TYR A  18
 FAD  A1001 (-3.7A)
None
None
None
 0.88A 6cduD-3h8lA:
undetectable
6cduE-3h8lA:
undetectable		 6cduD-3h8lA:
23.11
6cduE-3h8lA:
23.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DLZ_A_CYZA1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 3h8l NADH OXIDASE
(Acidianus
ambivalens) 		5 / 10 MET A  87
SER A  86
LEU A 274
SER A 277
ILE A 288
 None
 1.15A 6dlzA-3h8lA:
undetectable
6dlzD-3h8lA:
3.7		 6dlzA-3h8lA:
11.93
6dlzD-3h8lA:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DLZ_B_CYZB1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 3h8l NADH OXIDASE
(Acidianus
ambivalens) 		5 / 10 MET A  87
SER A  86
LEU A 274
SER A 277
ILE A 288
 None
 1.13A 6dlzB-3h8lA:
3.9
6dlzC-3h8lA:
2.3		 6dlzB-3h8lA:
11.93
6dlzC-3h8lA:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DLZ_C_CYZC1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 3h8l NADH OXIDASE
(Acidianus
ambivalens) 		5 / 10 ILE A 288
MET A  87
SER A  86
LEU A 274
SER A 277
 None
 1.15A 6dlzB-3h8lA:
3.9
6dlzC-3h8lA:
undetectable		 6dlzB-3h8lA:
11.93
6dlzC-3h8lA:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DLZ_D_CYZD1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 3h8l NADH OXIDASE
(Acidianus
ambivalens) 		5 / 11 ILE A 288
MET A  87
SER A  86
LEU A 274
SER A 277
 None
 1.13A 6dlzA-3h8lA:
4.3
6dlzD-3h8lA:
3.9		 6dlzA-3h8lA:
11.93
6dlzD-3h8lA:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DM0_A_CYZA1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 3h8l NADH OXIDASE
(Acidianus
ambivalens) 		5 / 9 MET A  87
SER A  86
LEU A 274
SER A 277
ILE A 288
 None
 1.15A 6dm0A-3h8lA:
2.3
6dm0D-3h8lA:
0.4		 6dm0A-3h8lA:
11.93
6dm0D-3h8lA:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DM0_C_CYZC1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 3h8l NADH OXIDASE
(Acidianus
ambivalens) 		5 / 9 ILE A 288
MET A  87
SER A  86
LEU A 274
SER A 277
 None
 1.14A 6dm0B-3h8lA:
0.6
6dm0C-3h8lA:
2.3		 6dm0B-3h8lA:
11.93
6dm0C-3h8lA:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DM1_A_CYZA1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 3h8l NADH OXIDASE
(Acidianus
ambivalens) 		5 / 10 MET A  87
SER A  86
LEU A 274
SER A 277
ILE A 288
 None
 1.15A 6dm1A-3h8lA:
undetectable
6dm1D-3h8lA:
undetectable		 6dm1A-3h8lA:
11.93
6dm1D-3h8lA:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DM1_B_CYZB1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 3h8l NADH OXIDASE
(Acidianus
ambivalens) 		5 / 10 MET A  87
SER A  86
LEU A 274
SER A 277
ILE A 288
 None
 1.13A 6dm1B-3h8lA:
undetectable
6dm1C-3h8lA:
2.3		 6dm1B-3h8lA:
11.93
6dm1C-3h8lA:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DM1_C_CYZC1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 3h8l NADH OXIDASE
(Acidianus
ambivalens) 		5 / 10 ILE A 288
MET A  87
SER A  86
LEU A 274
SER A 277
 None
 1.14A 6dm1B-3h8lA:
undetectable
6dm1C-3h8lA:
undetectable		 6dm1B-3h8lA:
11.93
6dm1C-3h8lA:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DM1_D_CYZD1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 3h8l NADH OXIDASE
(Acidianus
ambivalens) 		5 / 11 ILE A 288
MET A  87
SER A  86
LEU A 274
SER A 277
 None
 1.13A 6dm1A-3h8lA:
4.2
6dm1D-3h8lA:
undetectable		 6dm1A-3h8lA:
11.93
6dm1D-3h8lA:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DM2_A_CYZA1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 3h8l NADH OXIDASE
(Acidianus
ambivalens) 		5 / 9 MET A  87
SER A  86
LEU A 274
SER A 277
ILE A 288
 None
 1.07A 6dm2A-3h8lA:
2.1
6dm2D-3h8lA:
3.9		 6dm2A-3h8lA:
11.93
6dm2D-3h8lA:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DM2_B_CYZB1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 3h8l NADH OXIDASE
(Acidianus
ambivalens) 		5 / 10 MET A  87
SER A  86
LEU A 274
SER A 277
ILE A 288
 None
 1.06A 6dm2B-3h8lA:
undetectable
6dm2C-3h8lA:
2.3		 6dm2B-3h8lA:
11.93
6dm2C-3h8lA:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DM2_C_CYZC1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 3h8l NADH OXIDASE
(Acidianus
ambivalens) 		5 / 9 ILE A 288
MET A  87
SER A  86
LEU A 274
SER A 277
 None
 1.07A 6dm2B-3h8lA:
undetectable
6dm2C-3h8lA:
2.3		 6dm2B-3h8lA:
11.93
6dm2C-3h8lA:
11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DM2_D_CYZD1302_0
(GLUTAMATE RECEPTOR
2,VOLTAGE-DEPENDENT
CALCIUM CHANNEL
GAMMA-2 SUBUNIT)		 3h8l NADH OXIDASE
(Acidianus
ambivalens) 		5 / 10 ILE A 288
MET A  87
SER A  86
LEU A 274
SER A 277
 None
 1.07A 6dm2A-3h8lA:
2.3
6dm2D-3h8lA:
3.9		 6dm2A-3h8lA:
11.93
6dm2D-3h8lA:
11.93