SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3h8m'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1RU9_H_ACTH611_0 (IMMUNOGLOBULIN IGG2A, HEAVY CHAIN IMMUNOGLOBULIN IGG2A, LIGHT CHAIN)	3h8m	EPHRIN TYPE-A RECEPTOR 7 (Homo sapiens)	4 / 6	LEU A 952 TRP A 931 LEU A 932 PHE A 944	LEU A 952 ( 0.5A) TRP A 931 ( 0.5A) LEU A 932 ( 0.6A) PHE A 944 ( 1.4A)	1.30A	1ru9H-3h8mA: undetectable 1ru9L-3h8mA: undetectable	1ru9H-3h8mA: 14.41 1ru9L-3h8mA: 16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1RUK_L_ACTL611_0 (IMMUNOGLOBULIN IGG2A, HEAVY CHAIN IMMUNOGLOBULIN IGG2A, LIGHT CHAIN)	3h8m	EPHRIN TYPE-A RECEPTOR 7 (Homo sapiens)	4 / 6	LEU A 952 TRP A 931 LEU A 932 PHE A 944	LEU A 952 ( 0.5A) TRP A 931 ( 0.5A) LEU A 932 ( 0.6A) PHE A 944 ( 1.4A)	1.35A	1rukH-3h8mA: undetectable 1rukL-3h8mA: undetectable	1rukH-3h8mA: 14.41 1rukL-3h8mA: 16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3APV_B_TP0B190_1 (ALPHA-1-ACID GLYCOPROTEIN 2)	3h8m	EPHRIN TYPE-A RECEPTOR 7 (Homo sapiens)	5 / 12	PHE A 944 TYR A 949 VAL A 928 LEU A 989 ARG A 957	PHE A 944 ( 1.4A) TYR A 949 ( 1.3A) VAL A 928 ( 0.6A) LEU A 989 ( 0.5A) ARG A 957 ( 0.6A)	1.49A	3apvB-3h8mA: undetectable	3apvB-3h8mA: 17.35

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1RU9_H_ACTH611_0","IMMUNOGLOBULIN IGG2A, HEAVY CHAIN;IMMUNOGLOBULIN IGG2A, LIGHT CHAIN","3h8m","EPHRIN TYPE-A RECEPTOR 7","Homo sapiens",4,"LEU A 952;TRP A 931;LEU A 932;PHE A 944","LEU A 952 ( 0.5A);TRP A 931 ( 0.5A);LEU A 932 ( 0.6A);PHE A 944 ( 1.4A)","1.30A","1ru9H-3h8mA:undetectable;1ru9L-3h8mA:undetectable","1ru9H-3h8mA:14.41;1ru9L-3h8mA:16.67"],["1RUK_L_ACTL611_0","IMMUNOGLOBULIN IGG2A, HEAVY CHAIN;IMMUNOGLOBULIN IGG2A, LIGHT CHAIN","3h8m","EPHRIN TYPE-A RECEPTOR 7","Homo sapiens",4,"LEU A 952;TRP A 931;LEU A 932;PHE A 944","LEU A 952 ( 0.5A);TRP A 931 ( 0.5A);LEU A 932 ( 0.6A);PHE A 944 ( 1.4A)","1.35A","1rukH-3h8mA:undetectable;1rukL-3h8mA:undetectable","1rukH-3h8mA:14.41;1rukL-3h8mA:16.67"],["3APV_B_TP0B190_1","ALPHA-1-ACID GLYCOPROTEIN 2","3h8m","EPHRIN TYPE-A RECEPTOR 7","Homo sapiens",5,"PHE A 944;TYR A 949;VAL A 928;LEU A 989;ARG A 957","PHE A 944 ( 1.4A);TYR A 949 ( 1.3A);VAL A 928 ( 0.6A);LEU A 989 ( 0.5A);ARG A 957 ( 0.6A)","1.49A","3apvB-3h8mA:undetectable","3apvB-3h8mA:17.35"]]