SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3h8n'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_IMNA2001_1
(SERUM ALBUMIN)		 3h8n KILLER CELL
IMMUNOGLOBULIN-LIKE
RECEPTOR 2DS4
(Homo
sapiens) 		5 / 10 SER A 180
ALA A 152
ARG A 148
LEU A 126
LEU A 110
 None
 1.09A 2bxqA-3h8nA:
undetectable		 2bxqA-3h8nA:
16.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XF3_A_J01A500_1
(ORF12)		 3h8n KILLER CELL
IMMUNOGLOBULIN-LIKE
RECEPTOR 2DS4
(Homo
sapiens) 		5 / 10 ILE A 102
LEU A  97
LEU A  17
GLY A  15
ALA A  12
 None
 1.20A 2xf3A-3h8nA:
undetectable		 2xf3A-3h8nA:
18.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZI9_A_CL9A401_2
(DEOXYCYTIDINE KINASE)		 3h8n KILLER CELL
IMMUNOGLOBULIN-LIKE
RECEPTOR 2DS4
(Homo
sapiens) 		3 / 3 ASP A 163
PHE A 164
LEU A 166
 None
 0.62A 2zi9A-3h8nA:
undetectable		 2zi9A-3h8nA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WAN_C_ACTC303_0
(BRANCHPOINT-BRIDGING
PROTEIN)		 3h8n KILLER CELL
IMMUNOGLOBULIN-LIKE
RECEPTOR 2DS4
(Homo
sapiens) 		3 / 3 ASP A  98
ARG A  78
PRO A  96
 None
 1.06A 4wanC-3h8nA:
undetectable		 4wanC-3h8nA:
23.98