SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3h8t'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DPM_A_SAMA300_0
(PROTEIN
(ADENINE-SPECIFIC
METHYLTRANSFERASE
DPNII 1))		 3h8t HMUY
(Porphyromonas
gingivalis) 		5 / 12 GLY A 187
GLY A  95
GLY A  94
PHE A  98
PRO A 111
 None
 1.09A 2dpmA-3h8tA:
undetectable		 2dpmA-3h8tA:
20.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_E_W9TE506_1
(HEMOLYTIC LECTIN
CEL-III)		 3h8t HMUY
(Porphyromonas
gingivalis) 		4 / 6 THR A 116
CYH A  86
GLY A  87
ASP A 118
 None
 0.62A 3w9tE-3h8tA:
undetectable		 3w9tE-3h8tA:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_F_W9TF512_1
(HEMOLYTIC LECTIN
CEL-III)		 3h8t HMUY
(Porphyromonas
gingivalis) 		4 / 6 THR A 116
CYH A  86
GLY A  87
ASP A 118
 None
 0.62A 3w9tF-3h8tA:
undetectable		 3w9tF-3h8tA:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N48_A_SAMA601_0
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 3h8t HMUY
(Porphyromonas
gingivalis) 		5 / 12 GLY A 184
GLY A 187
ASN A  85
ILE A 147
THR A 148
 None
 1.23A 4n48A-3h8tA:
undetectable		 4n48A-3h8tA:
18.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CR1_A_T44A201_1
(TRANSTHYRETIN)		 3h8t HMUY
(Porphyromonas
gingivalis) 		4 / 5 LYS A 177
LEU A 175
LEU A 162
VAL A 192
 None
 1.11A 5cr1A-3h8tA:
undetectable		 5cr1A-3h8tA:
20.21