SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3h90'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7B_A_HLTA4002_1
(SERUM ALBUMIN)		 3h90 FERROUS-IRON EFFLUX
PUMP FIEF
(Escherichia
coli) 		4 / 4 ARG A 148
ALA A 149
ALA A 201
GLU A 200
 None
 0.99A 1e7bA-3h90A:
2.0		 1e7bA-3h90A:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7B_B_HLTB4002_1
(SERUM ALBUMIN)		 3h90 FERROUS-IRON EFFLUX
PUMP FIEF
(Escherichia
coli) 		4 / 4 ARG A 148
ALA A 149
ALA A 201
GLU A 200
 None
 1.09A 1e7bB-3h90A:
undetectable		 1e7bB-3h90A:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7C_A_HLTA4002_1
(SERUM ALBUMIN)		 3h90 FERROUS-IRON EFFLUX
PUMP FIEF
(Escherichia
coli) 		4 / 5 ARG A 148
ALA A 149
ALA A 201
GLU A 200
 None
 1.11A 1e7cA-3h90A:
2.4		 1e7cA-3h90A:
20.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BYO_A_LNLA1216_1
(LIPOPROTEIN LPPX)		 3h90 FERROUS-IRON EFFLUX
PUMP FIEF
(Escherichia
coli) 		4 / 5 LEU A  47
ILE A  50
LEU A  54
SER A  53
 None
 0.98A 2byoA-3h90A:
undetectable		 2byoA-3h90A:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_1
(GENOME POLYPROTEIN)		 3h90 FERROUS-IRON EFFLUX
PUMP FIEF
(Escherichia
coli) 		5 / 12 GLN A 143
VAL A  60
GLY A 240
ALA A  83
ALA A  82
 None
 1.01A 3keeB-3h90A:
undetectable		 3keeB-3h90A:
23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP2_A_PNNA5001_0
(TRANSCRIPTIONAL
REGULATOR TCAR)		 3h90 FERROUS-IRON EFFLUX
PUMP FIEF
(Escherichia
coli) 		4 / 8 THR A 128
LEU A 131
GLN A 135
HIS A 153
 None
None
None
ZN  A   4 (-3.5A)
 1.11A 3kp2A-3h90A:
undetectable
3kp2B-3h90A:
undetectable		 3kp2A-3h90A:
18.25
3kp2B-3h90A:
18.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NUV_A_ASDA126_1
(STEROID
DELTA-ISOMERASE)		 3h90 FERROUS-IRON EFFLUX
PUMP FIEF
(Escherichia
coli) 		5 / 12 SER A  21
LEU A 131
PHE A 134
VAL A 138
ALA A 146
 None
 1.18A 3nuvA-3h90A:
undetectable		 3nuvA-3h90A:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B53_B_ACTB1445_0
(IG GAMMA-4 CHAIN C
REGION)		 3h90 FERROUS-IRON EFFLUX
PUMP FIEF
(Escherichia
coli) 		3 / 3 GLU A  79
GLY A 240
SER A  63
 None
 0.64A 4b53B-3h90A:
undetectable		 4b53B-3h90A:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZT_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 2)		 3h90 FERROUS-IRON EFFLUX
PUMP FIEF
(Escherichia
coli) 		5 / 12 ILE A  90
GLN A 145
VAL A  59
LEU A 205
LEU A  84
 None
 1.46A 4qztA-3h90A:
undetectable		 4qztA-3h90A:
14.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U15_A_0HKA2001_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3)		 3h90 FERROUS-IRON EFFLUX
PUMP FIEF
(Escherichia
coli) 		5 / 12 ASP A 157
TYR A 154
THR A  17
ALA A  18
ALA A  20
 ZN  A   4 (-2.2A)
None
None
None
None
 1.37A 4u15A-3h90A:
undetectable		 4u15A-3h90A:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U15_B_0HKB1201_1
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3)		 3h90 FERROUS-IRON EFFLUX
PUMP FIEF
(Escherichia
coli) 		5 / 12 ASP A 157
TYR A 154
THR A  17
ALA A  18
ALA A  20
 ZN  A   4 (-2.2A)
None
None
None
None
 1.34A 4u15B-3h90A:
undetectable		 4u15B-3h90A:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBR_A_NPSA603_1
(SERUM ALBUMIN)		 3h90 FERROUS-IRON EFFLUX
PUMP FIEF
(Escherichia
coli) 		5 / 10 ALA A  82
ALA A 149
SER A 204
LEU A 205
ALA A 201
 None
 1.06A 4zbrA-3h90A:
2.5		 4zbrA-3h90A:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HRQ_E_IPHE101_0
(INSULIN A-CHAIN
INSULIN B-CHAIN)		 3h90 FERROUS-IRON EFFLUX
PUMP FIEF
(Escherichia
coli) 		4 / 7 ILE A 245
HIS A 248
LEU A 249
ALA A 231
 None
ZN  A 293 (-3.2A)
None
None
 0.98A 5hrqE-3h90A:
undetectable
5hrqF-3h90A:
undetectable
5hrqJ-3h90A:
undetectable		 5hrqE-3h90A:
5.12
5hrqF-3h90A:
6.05
5hrqJ-3h90A:
6.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MA6_A_MYTA603_0
(CYTOCHROME P450 3A4)		 3h90 FERROUS-IRON EFFLUX
PUMP FIEF
(Escherichia
coli) 		4 / 6 ARG A  11
ALA A  13
THR A 142
ALA A 146
 None
 1.12A 6ma6A-3h90A:
undetectable		 6ma6A-3h90A:
15.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3h90 FERROUS-IRON EFFLUX
PUMP FIEF
(Escherichia
coli) 		4 / 6 ILE A  50
LEU A  25
TYR A 154
THR A  17
 None
 1.14A 6nmfN-3h90A:
1.8
6nmfW-3h90A:
undetectable		 6nmfN-3h90A:
19.46
6nmfW-3h90A:
12.23