SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3h95'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JG3_A_ADNA500_1
(PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE)		 3h95 NUCLEOSIDE
DIPHOSPHATE-LINKED
MOIETY X MOTIF 6
(Homo
sapiens) 		5 / 11 GLN A 143
GLY A 145
LEU A 177
ASP A 186
GLY A 185
 None
 1.10A 1jg3A-3h95A:
undetectable		 1jg3A-3h95A:
24.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_A_SWFA502_1
(CYTOCHROME P450 2C9)		 3h95 NUCLEOSIDE
DIPHOSPHATE-LINKED
MOIETY X MOTIF 6
(Homo
sapiens) 		5 / 12 PHE A 151
LEU A 229
ALA A 149
LEU A 270
PHE A 279
 None
 0.95A 1og5A-3h95A:
undetectable		 1og5A-3h95A:
18.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OG5_B_SWFB502_1
(CYTOCHROME P450 2C9)		 3h95 NUCLEOSIDE
DIPHOSPHATE-LINKED
MOIETY X MOTIF 6
(Homo
sapiens) 		5 / 12 PHE A 151
LEU A 229
ALA A 149
LEU A 270
PHE A 279
 None
 0.89A 1og5B-3h95A:
undetectable		 1og5B-3h95A:
18.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_B_URFB2011_1
(URIDINE
PHOSPHORYLASE)		 3h95 NUCLEOSIDE
DIPHOSPHATE-LINKED
MOIETY X MOTIF 6
(Homo
sapiens) 		4 / 8 GLY A 145
GLN A 143
ILE A 225
VAL A 146
 None
 0.94A 1rxcB-3h95A:
undetectable		 1rxcB-3h95A:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_C_URFC2081_1
(URIDINE
PHOSPHORYLASE)		 3h95 NUCLEOSIDE
DIPHOSPHATE-LINKED
MOIETY X MOTIF 6
(Homo
sapiens) 		4 / 7 GLY A 145
GLN A 143
ILE A 225
VAL A 146
 None
 0.95A 1rxcC-3h95A:
undetectable		 1rxcC-3h95A:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_D_URFD2021_1
(URIDINE
PHOSPHORYLASE)		 3h95 NUCLEOSIDE
DIPHOSPHATE-LINKED
MOIETY X MOTIF 6
(Homo
sapiens) 		4 / 7 GLY A 145
GLN A 143
ILE A 225
VAL A 146
 None
 0.97A 1rxcD-3h95A:
undetectable		 1rxcD-3h95A:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_E_URFE2031_1
(URIDINE
PHOSPHORYLASE)		 3h95 NUCLEOSIDE
DIPHOSPHATE-LINKED
MOIETY X MOTIF 6
(Homo
sapiens) 		4 / 8 GLY A 145
GLN A 143
ILE A 225
VAL A 146
 None
 0.96A 1rxcE-3h95A:
undetectable		 1rxcE-3h95A:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_F_URFF2001_1
(URIDINE
PHOSPHORYLASE)		 3h95 NUCLEOSIDE
DIPHOSPHATE-LINKED
MOIETY X MOTIF 6
(Homo
sapiens) 		4 / 7 GLY A 145
GLN A 143
ILE A 225
VAL A 146
 None
 0.98A 1rxcF-3h95A:
undetectable		 1rxcF-3h95A:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_I_URFI2041_1
(URIDINE
PHOSPHORYLASE)		 3h95 NUCLEOSIDE
DIPHOSPHATE-LINKED
MOIETY X MOTIF 6
(Homo
sapiens) 		4 / 8 GLY A 145
GLN A 143
ILE A 225
VAL A 146
 None
 0.93A 1rxcI-3h95A:
undetectable		 1rxcI-3h95A:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_K_URFK2061_1
(URIDINE
PHOSPHORYLASE)		 3h95 NUCLEOSIDE
DIPHOSPHATE-LINKED
MOIETY X MOTIF 6
(Homo
sapiens) 		4 / 8 GLY A 145
GLN A 143
ILE A 225
VAL A 146
 None
 0.94A 1rxcK-3h95A:
undetectable		 1rxcK-3h95A:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_L_URFL2071_1
(URIDINE
PHOSPHORYLASE)		 3h95 NUCLEOSIDE
DIPHOSPHATE-LINKED
MOIETY X MOTIF 6
(Homo
sapiens) 		4 / 7 GLY A 145
GLN A 143
ILE A 225
VAL A 146
 None
 0.96A 1rxcL-3h95A:
undetectable		 1rxcL-3h95A:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_B_TRPB1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3h95 NUCLEOSIDE
DIPHOSPHATE-LINKED
MOIETY X MOTIF 6
(Homo
sapiens) 		4 / 8 ASP A 183
ILE A 184
VAL A 146
GLN A 143
 None
 0.78A 3fi0B-3h95A:
undetectable		 3fi0B-3h95A:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_E_TRPE1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3h95 NUCLEOSIDE
DIPHOSPHATE-LINKED
MOIETY X MOTIF 6
(Homo
sapiens) 		4 / 7 ASP A 183
ILE A 184
VAL A 146
GLN A 143
 None
 0.83A 3fi0E-3h95A:
undetectable		 3fi0E-3h95A:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FI0_I_TRPI1001_0
(TRYPTOPHANYL-TRNA
SYNTHETASE)		 3h95 NUCLEOSIDE
DIPHOSPHATE-LINKED
MOIETY X MOTIF 6
(Homo
sapiens) 		4 / 8 ASP A 183
ILE A 184
VAL A 146
GLN A 143
 None
 0.79A 3fi0I-3h95A:
undetectable		 3fi0I-3h95A:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_A_URFA254_1
(URIDINE
PHOSPHORYLASE)		 3h95 NUCLEOSIDE
DIPHOSPHATE-LINKED
MOIETY X MOTIF 6
(Homo
sapiens) 		4 / 6 GLY A 145
GLN A 143
ILE A 225
VAL A 146
 None
 0.96A 3kvvA-3h95A:
undetectable		 3kvvA-3h95A:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_B_URFB254_1
(URIDINE
PHOSPHORYLASE)		 3h95 NUCLEOSIDE
DIPHOSPHATE-LINKED
MOIETY X MOTIF 6
(Homo
sapiens) 		4 / 6 GLY A 145
GLN A 143
ILE A 225
VAL A 146
 None
 0.94A 3kvvB-3h95A:
undetectable		 3kvvB-3h95A:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_C_URFC254_1
(URIDINE
PHOSPHORYLASE)		 3h95 NUCLEOSIDE
DIPHOSPHATE-LINKED
MOIETY X MOTIF 6
(Homo
sapiens) 		4 / 6 GLY A 145
GLN A 143
ILE A 225
VAL A 146
 None
 0.94A 3kvvC-3h95A:
undetectable		 3kvvC-3h95A:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_D_URFD254_1
(URIDINE
PHOSPHORYLASE)		 3h95 NUCLEOSIDE
DIPHOSPHATE-LINKED
MOIETY X MOTIF 6
(Homo
sapiens) 		4 / 6 GLY A 145
GLN A 143
ILE A 225
VAL A 146
 None
 0.93A 3kvvD-3h95A:
undetectable		 3kvvD-3h95A:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_E_URFE254_1
(URIDINE
PHOSPHORYLASE)		 3h95 NUCLEOSIDE
DIPHOSPHATE-LINKED
MOIETY X MOTIF 6
(Homo
sapiens) 		4 / 6 GLY A 145
GLN A 143
ILE A 225
VAL A 146
 None
 0.97A 3kvvE-3h95A:
undetectable		 3kvvE-3h95A:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KVV_F_URFF254_1
(URIDINE
PHOSPHORYLASE)		 3h95 NUCLEOSIDE
DIPHOSPHATE-LINKED
MOIETY X MOTIF 6
(Homo
sapiens) 		4 / 6 GLY A 145
GLN A 143
ILE A 225
VAL A 146
 None
 0.95A 3kvvF-3h95A:
undetectable		 3kvvF-3h95A:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D9H_A_ADNA301_1
(PURINE NUCLEOSIDE
PHOSPHORYLASE
DEOD-TYPE)		 3h95 NUCLEOSIDE
DIPHOSPHATE-LINKED
MOIETY X MOTIF 6
(Homo
sapiens) 		5 / 11 GLY A 148
VAL A 192
GLU A 191
GLU A 182
VAL A 150
 None
 1.29A 4d9hA-3h95A:
undetectable		 4d9hA-3h95A:
26.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_A_URFA1301_1
(URIDINE
PHOSPHORYLASE)		 3h95 NUCLEOSIDE
DIPHOSPHATE-LINKED
MOIETY X MOTIF 6
(Homo
sapiens) 		4 / 8 GLY A 145
GLN A 143
ILE A 225
VAL A 146
 None
 0.99A 4e1vA-3h95A:
undetectable		 4e1vA-3h95A:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_B_URFB1301_1
(URIDINE
PHOSPHORYLASE)		 3h95 NUCLEOSIDE
DIPHOSPHATE-LINKED
MOIETY X MOTIF 6
(Homo
sapiens) 		4 / 7 GLY A 145
GLN A 143
ILE A 225
VAL A 146
 None
 0.94A 4e1vB-3h95A:
undetectable		 4e1vB-3h95A:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_C_URFC1301_1
(URIDINE
PHOSPHORYLASE)		 3h95 NUCLEOSIDE
DIPHOSPHATE-LINKED
MOIETY X MOTIF 6
(Homo
sapiens) 		4 / 8 GLY A 145
GLN A 143
ILE A 225
VAL A 146
 None
 0.98A 4e1vC-3h95A:
undetectable		 4e1vC-3h95A:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_D_URFD1301_1
(URIDINE
PHOSPHORYLASE)		 3h95 NUCLEOSIDE
DIPHOSPHATE-LINKED
MOIETY X MOTIF 6
(Homo
sapiens) 		4 / 8 GLY A 145
GLN A 143
ILE A 225
VAL A 146
 None
 0.96A 4e1vD-3h95A:
undetectable		 4e1vD-3h95A:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_E_URFE1301_1
(URIDINE
PHOSPHORYLASE)		 3h95 NUCLEOSIDE
DIPHOSPHATE-LINKED
MOIETY X MOTIF 6
(Homo
sapiens) 		4 / 8 GLY A 145
GLN A 143
ILE A 225
VAL A 146
 None
 0.96A 4e1vE-3h95A:
undetectable		 4e1vE-3h95A:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_F_URFF1301_1
(URIDINE
PHOSPHORYLASE)		 3h95 NUCLEOSIDE
DIPHOSPHATE-LINKED
MOIETY X MOTIF 6
(Homo
sapiens) 		4 / 6 GLY A 145
GLN A 143
ILE A 225
VAL A 146
 None
 0.95A 4e1vF-3h95A:
undetectable		 4e1vF-3h95A:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_G_URFG1301_1
(URIDINE
PHOSPHORYLASE)		 3h95 NUCLEOSIDE
DIPHOSPHATE-LINKED
MOIETY X MOTIF 6
(Homo
sapiens) 		4 / 8 GLY A 145
GLN A 143
ILE A 225
VAL A 146
 None
 0.97A 4e1vG-3h95A:
undetectable		 4e1vG-3h95A:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_H_URFH1301_1
(URIDINE
PHOSPHORYLASE)		 3h95 NUCLEOSIDE
DIPHOSPHATE-LINKED
MOIETY X MOTIF 6
(Homo
sapiens) 		4 / 8 GLY A 145
GLN A 143
ILE A 225
VAL A 146
 None
 0.95A 4e1vH-3h95A:
undetectable		 4e1vH-3h95A:
22.01