SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3h9c'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FFY_A_MRCA1993_1
(ISOLEUCYL-TRNA
SYNTHETASE)		 3h9c METHIONYL-TRNA
SYNTHETASE
(Escherichia
coli) 		5 / 12 HIS A  21
GLY A  23
GLY A 294
HIS A 323
VAL A 326
 None
 0.83A 1ffyA-3h9cA:
22.5		 1ffyA-3h9cA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MAA_B_DMEB996_1
(ACETYLCHOLINESTERASE)		 3h9c METHIONYL-TRNA
SYNTHETASE
(Escherichia
coli) 		4 / 6 GLU A 100
ILE A 242
TYR A 249
GLY A 247
 None
 1.17A 1maaB-3h9cA:
0.3
1maaD-3h9cA:
undetectable		 1maaB-3h9cA:
22.61
1maaD-3h9cA:
22.61
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PG2_A_ADNA552_1
(METHIONYL-TRNA
SYNTHETASE)		 3h9c METHIONYL-TRNA
SYNTHETASE
(Escherichia
coli) 		9 / 11 ALA A  12
HIS A  21
GLY A  23
GLU A  27
GLY A 294
ILE A 297
HIS A 323
TYR A 325
VAL A 326
 None
 0.48A 1pg2A-3h9cA:
57.0		 1pg2A-3h9cA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PG2_A_ADNA552_1
(METHIONYL-TRNA
SYNTHETASE)		 3h9c METHIONYL-TRNA
SYNTHETASE
(Escherichia
coli) 		9 / 11 ALA A  12
HIS A  21
GLY A  23
HIS A  24
GLU A  27
GLY A 294
ILE A 297
HIS A 323
VAL A 326
 None
 0.33A 1pg2A-3h9cA:
57.0		 1pg2A-3h9cA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1PG2_A_ADNA552_1
(METHIONYL-TRNA
SYNTHETASE)		 3h9c METHIONYL-TRNA
SYNTHETASE
(Escherichia
coli) 		5 / 11 HIS A  21
GLY A  23
ASP A 296
TYR A 325
VAL A 326
 None
 0.91A 1pg2A-3h9cA:
57.0		 1pg2A-3h9cA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QU2_A_MRCA1993_1
(ISOLEUCYL-TRNA
SYNTHETASE)		 3h9c METHIONYL-TRNA
SYNTHETASE
(Escherichia
coli) 		6 / 12 HIS A  21
GLY A  23
HIS A  24
GLY A 294
HIS A 323
VAL A 326
 None
 0.78A 1qu2A-3h9cA:
22.5		 1qu2A-3h9cA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QU3_A_MRCA993_1
(ISOLEUCYL-TRNA
SYNTHETASE)		 3h9c METHIONYL-TRNA
SYNTHETASE
(Escherichia
coli) 		5 / 12 HIS A  21
GLY A  23
HIS A  24
HIS A 323
VAL A 326
 None
 0.83A 1qu3A-3h9cA:
7.2		 1qu3A-3h9cA:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SN0_B_T44B602_1
(TRANSTHYRETIN)		 3h9c METHIONYL-TRNA
SYNTHETASE
(Escherichia
coli) 		4 / 7 LEU A 487
GLU A 443
LEU A 417
ALA A 451
 None
 0.96A 1sn0B-3h9cA:
undetectable
1sn0D-3h9cA:
undetectable		 1sn0B-3h9cA:
15.80
1sn0D-3h9cA:
15.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TYR_A_9CRA131_1
(TRANSTHYRETIN)		 3h9c METHIONYL-TRNA
SYNTHETASE
(Escherichia
coli) 		4 / 6 LEU A   8
ALA A 287
LEU A 289
SER A 318
 None
 1.22A 1tyrA-3h9cA:
undetectable		 1tyrA-3h9cA:
12.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QWX_A_ML1A233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3h9c METHIONYL-TRNA
SYNTHETASE
(Escherichia
coli) 		4 / 8 ILE A 400
PHE A 505
GLY A 480
ILE A 476
 None
 0.99A 2qwxA-3h9cA:
2.8
2qwxB-3h9cA:
2.4		 2qwxA-3h9cA:
18.55
2qwxB-3h9cA:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_A_RBFA200_1
(DODECIN)		 3h9c METHIONYL-TRNA
SYNTHETASE
(Escherichia
coli) 		4 / 8 GLN A 213
ARG A 435
HIS A 323
GLN A  30
 None
 1.02A 2vxaA-3h9cA:
undetectable
2vxaC-3h9cA:
undetectable
2vxaE-3h9cA:
undetectable		 2vxaA-3h9cA:
9.16
2vxaC-3h9cA:
9.16
2vxaE-3h9cA:
9.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_B_RBFB200_1
(DODECIN)		 3h9c METHIONYL-TRNA
SYNTHETASE
(Escherichia
coli) 		4 / 8 GLN A 213
ARG A 435
HIS A 323
GLN A  30
 None
 1.01A 2vxaA-3h9cA:
undetectable
2vxaB-3h9cA:
undetectable
2vxaK-3h9cA:
undetectable		 2vxaA-3h9cA:
9.16
2vxaB-3h9cA:
9.16
2vxaK-3h9cA:
9.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_C_RBFC200_1
(DODECIN)		 3h9c METHIONYL-TRNA
SYNTHETASE
(Escherichia
coli) 		4 / 8 GLN A 213
ARG A 435
HIS A 323
GLN A  30
 None
 1.01A 2vxaB-3h9cA:
undetectable
2vxaC-3h9cA:
undetectable
2vxaG-3h9cA:
undetectable		 2vxaB-3h9cA:
9.16
2vxaC-3h9cA:
9.16
2vxaG-3h9cA:
9.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_D_RBFD200_1
(DODECIN)		 3h9c METHIONYL-TRNA
SYNTHETASE
(Escherichia
coli) 		4 / 8 GLN A 213
ARG A 435
HIS A 323
GLN A  30
 None
 1.01A 2vxaD-3h9cA:
undetectable
2vxaF-3h9cA:
undetectable
2vxaI-3h9cA:
undetectable		 2vxaD-3h9cA:
9.16
2vxaF-3h9cA:
9.16
2vxaI-3h9cA:
9.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_E_RBFE200_1
(DODECIN)		 3h9c METHIONYL-TRNA
SYNTHETASE
(Escherichia
coli) 		4 / 8 GLN A 213
ARG A 435
HIS A 323
GLN A  30
 None
 1.02A 2vxaD-3h9cA:
undetectable
2vxaE-3h9cA:
undetectable
2vxaL-3h9cA:
undetectable		 2vxaD-3h9cA:
9.16
2vxaE-3h9cA:
9.16
2vxaL-3h9cA:
9.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_G_RBFG200_1
(DODECIN)		 3h9c METHIONYL-TRNA
SYNTHETASE
(Escherichia
coli) 		4 / 8 ARG A 435
HIS A 323
GLN A  30
GLN A 213
 None
 0.98A 2vxaF-3h9cA:
undetectable
2vxaG-3h9cA:
undetectable
2vxaI-3h9cA:
undetectable		 2vxaF-3h9cA:
9.16
2vxaG-3h9cA:
9.16
2vxaI-3h9cA:
9.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_H_RBFH200_1
(DODECIN)		 3h9c METHIONYL-TRNA
SYNTHETASE
(Escherichia
coli) 		4 / 8 ARG A 435
HIS A 323
GLN A  30
GLN A 213
 None
 0.99A 2vxaB-3h9cA:
undetectable
2vxaG-3h9cA:
undetectable
2vxaH-3h9cA:
undetectable		 2vxaB-3h9cA:
9.16
2vxaG-3h9cA:
9.16
2vxaH-3h9cA:
9.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_I_RBFI200_1
(DODECIN)		 3h9c METHIONYL-TRNA
SYNTHETASE
(Escherichia
coli) 		4 / 8 GLN A 213
ARG A 435
HIS A 323
GLN A  30
 None
 1.00A 2vxaH-3h9cA:
undetectable
2vxaI-3h9cA:
undetectable
2vxaJ-3h9cA:
undetectable		 2vxaH-3h9cA:
9.16
2vxaI-3h9cA:
9.16
2vxaJ-3h9cA:
9.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_J_RBFJ200_1
(DODECIN)		 3h9c METHIONYL-TRNA
SYNTHETASE
(Escherichia
coli) 		4 / 8 ARG A 435
HIS A 323
GLN A  30
GLN A 213
 None
 1.02A 2vxaD-3h9cA:
undetectable
2vxaJ-3h9cA:
undetectable
2vxaL-3h9cA:
undetectable		 2vxaD-3h9cA:
9.16
2vxaJ-3h9cA:
9.16
2vxaL-3h9cA:
9.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_K_RBFK200_1
(DODECIN)		 3h9c METHIONYL-TRNA
SYNTHETASE
(Escherichia
coli) 		4 / 8 ARG A 435
HIS A 323
GLN A  30
GLN A 213
 None
 1.00A 2vxaH-3h9cA:
undetectable
2vxaJ-3h9cA:
undetectable
2vxaK-3h9cA:
undetectable		 2vxaH-3h9cA:
9.16
2vxaJ-3h9cA:
9.16
2vxaK-3h9cA:
9.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_L_RBFL200_1
(DODECIN)		 3h9c METHIONYL-TRNA
SYNTHETASE
(Escherichia
coli) 		4 / 8 ARG A 435
HIS A 323
GLN A  30
GLN A 213
 None
 0.99A 2vxaA-3h9cA:
undetectable
2vxaK-3h9cA:
undetectable
2vxaL-3h9cA:
undetectable		 2vxaA-3h9cA:
9.16
2vxaK-3h9cA:
9.16
2vxaL-3h9cA:
9.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W9S_E_TOPE1160_1
(DIHYDROFOLATE
REDUCTASE TYPE 1
FROM TN4003)		 3h9c METHIONYL-TRNA
SYNTHETASE
(Escherichia
coli) 		4 / 8 ILE A  58
ALA A  62
ILE A  73
PHE A 238
 None
 0.79A 2w9sE-3h9cA:
undetectable		 2w9sE-3h9cA:
16.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X1L_A_ADNA601_1
(METHIONYL-TRNA
SYNTHETASE)		 3h9c METHIONYL-TRNA
SYNTHETASE
(Escherichia
coli) 		8 / 11 ALA A  12
HIS A  21
GLY A  23
HIS A  24
GLU A  27
GLY A 294
ILE A 297
HIS A 323
 None
 0.38A 2x1lA-3h9cA:
37.9		 2x1lA-3h9cA:
28.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X1L_A_ADNA601_1
(METHIONYL-TRNA
SYNTHETASE)		 3h9c METHIONYL-TRNA
SYNTHETASE
(Escherichia
coli) 		5 / 11 HIS A  21
GLY A  23
GLY A 294
ASP A 296
HIS A 323
 None
 1.05A 2x1lA-3h9cA:
37.9		 2x1lA-3h9cA:
28.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X1L_B_ADNB601_1
(METHIONYL-TRNA
SYNTHETASE)		 3h9c METHIONYL-TRNA
SYNTHETASE
(Escherichia
coli) 		8 / 12 ALA A  12
HIS A  21
GLY A  23
HIS A  24
GLU A  27
GLY A 294
ILE A 297
HIS A 323
 None
 0.33A 2x1lB-3h9cA:
40.5		 2x1lB-3h9cA:
28.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X1L_C_ADNC601_1
(METHIONYL-TRNA
SYNTHETASE)		 3h9c METHIONYL-TRNA
SYNTHETASE
(Escherichia
coli) 		8 / 11 ALA A  12
HIS A  21
GLY A  23
HIS A  24
GLU A  27
GLY A 294
ILE A 297
HIS A 323
 None
 0.39A 2x1lC-3h9cA:
40.3		 2x1lC-3h9cA:
28.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2N_B_X2NB1479_1
(LANOSTEROL
14-ALPHA-DEMETHYLASE)		 3h9c METHIONYL-TRNA
SYNTHETASE
(Escherichia
coli) 		5 / 12 MET A 308
PHE A 304
ALA A 256
THR A  97
MET A 261
 None
 1.29A 2x2nB-3h9cA:
undetectable		 2x2nB-3h9cA:
20.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2N_D_X2ND1479_1
(LANOSTEROL
14-ALPHA-DEMETHYLASE)		 3h9c METHIONYL-TRNA
SYNTHETASE
(Escherichia
coli) 		5 / 12 MET A 308
PHE A 304
ALA A 256
THR A  97
MET A 261
 None
 1.32A 2x2nD-3h9cA:
undetectable		 2x2nD-3h9cA:
20.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XF3_A_J01A500_1
(ORF12)		 3h9c METHIONYL-TRNA
SYNTHETASE
(Escherichia
coli) 		5 / 10 HIS A 323
VAL A 326
ILE A 370
LEU A 363
ALA A  31
 None
 1.07A 2xf3A-3h9cA:
undetectable		 2xf3A-3h9cA:
21.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B0W_A_DGXA1_2
(NUCLEAR RECEPTOR
ROR-GAMMA)		 3h9c METHIONYL-TRNA
SYNTHETASE
(Escherichia
coli) 		3 / 3 TRP A 512
VAL A 389
ARG A 395
 None
 0.92A 3b0wA-3h9cA:
undetectable		 3b0wA-3h9cA:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H52_D_486D2_2
(GLUCOCORTICOID
RECEPTOR)		 3h9c METHIONYL-TRNA
SYNTHETASE
(Escherichia
coli) 		4 / 5 LEU A 392
ASN A 396
TRP A 461
TYR A 454
 None
 1.43A 3h52D-3h9cA:
0.0		 3h52D-3h9cA:
18.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PHA_B_ACRB701_1
(ALPHA-GLUCOSIDASE)		 3h9c METHIONYL-TRNA
SYNTHETASE
(Escherichia
coli) 		5 / 12 ILE A 109
ILE A  73
ILE A  58
ASP A 255
PHE A 240
 None
 1.35A 3phaB-3h9cA:
undetectable		 3phaB-3h9cA:
22.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ARC_A_LEUA1001_0
(LEUCINE--TRNA LIGASE)		 3h9c METHIONYL-TRNA
SYNTHETASE
(Escherichia
coli) 		4 / 7 TYR A  94
ASP A  51
HIS A  28
HIS A  24
 None
 1.12A 4arcA-3h9cA:
27.6		 4arcA-3h9cA:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J7X_B_SASB804_2
(SEPIAPTERIN
REDUCTASE)		 3h9c METHIONYL-TRNA
SYNTHETASE
(Escherichia
coli) 		3 / 3 LEU A 412
MET A 479
ASP A 513
 None
 0.79A 4j7xB-3h9cA:
undetectable		 4j7xB-3h9cA:
21.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCN_A_MTLA804_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3h9c METHIONYL-TRNA
SYNTHETASE
(Escherichia
coli) 		4 / 6 ARG A 403
GLU A 467
ASP A 470
ASP A 472
 None
 1.25A 4kcnA-3h9cA:
undetectable		 4kcnA-3h9cA:
22.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCN_B_MTLB805_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3h9c METHIONYL-TRNA
SYNTHETASE
(Escherichia
coli) 		4 / 6 ARG A 403
GLU A 467
ASP A 470
ASP A 472
 None
 1.26A 4kcnB-3h9cA:
undetectable		 4kcnB-3h9cA:
22.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XEY_A_1N1A601_2
(TYROSINE-PROTEIN
KINASE ABL1)		 3h9c METHIONYL-TRNA
SYNTHETASE
(Escherichia
coli) 		3 / 3 MET A 184
ASP A 138
PHE A 140
 None
 0.75A 4xeyA-3h9cA:
undetectable		 4xeyA-3h9cA:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XEY_B_1N1B601_2
(TYROSINE-PROTEIN
KINASE ABL1)		 3h9c METHIONYL-TRNA
SYNTHETASE
(Escherichia
coli) 		3 / 3 MET A 184
ASP A 138
PHE A 140
 None
 0.72A 4xeyB-3h9cA:
undetectable		 4xeyB-3h9cA:
21.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XO7_B_ASDB402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 3h9c METHIONYL-TRNA
SYNTHETASE
(Escherichia
coli) 		4 / 7 TYR A 260
ILE A 109
HIS A 291
LEU A 289
 None
 1.24A 4xo7B-3h9cA:
undetectable		 4xo7B-3h9cA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F9Z_B_HFGB703_0
(AMINOACYL-TRNA
SYNTHETASE)		 3h9c METHIONYL-TRNA
SYNTHETASE
(Escherichia
coli) 		5 / 12 PHE A  47
SER A  90
GLU A 433
PHE A 437
GLY A 429
 None
 1.08A 5f9zB-3h9cA:
undetectable		 5f9zB-3h9cA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GQB_A_GCSA605_1
(CHITINASE)		 3h9c METHIONYL-TRNA
SYNTHETASE
(Escherichia
coli) 		3 / 3 TRP A 281
ILE A 109
SER A 312
 None
 0.96A 5gqbA-3h9cA:
undetectable		 5gqbA-3h9cA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HG0_B_SAMB301_0
(PANTOTHENATE
SYNTHETASE)		 3h9c METHIONYL-TRNA
SYNTHETASE
(Escherichia
coli) 		5 / 12 HIS A  21
GLY A  23
HIS A  24
VAL A 252
GLY A 294
 None
 1.03A 5hg0B-3h9cA:
4.9		 5hg0B-3h9cA:
19.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HWA_A_GCSA302_1
(CHITOSANASE)		 3h9c METHIONYL-TRNA
SYNTHETASE
(Escherichia
coli) 		4 / 7 THR A  97
ASP A  52
ASP A 255
GLY A  55
 None
 0.89A 5hwaA-3h9cA:
undetectable		 5hwaA-3h9cA:
19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ICX_F_SC2F1_1
(CETUXIMAB FAB LIGHT
CHAIN
MEDITOPE)		 3h9c METHIONYL-TRNA
SYNTHETASE
(Escherichia
coli) 		3 / 3 VAL A 463
GLN A 474
CYH A 477
 None
 0.82A 5icxC-3h9cA:
undetectable
5icxF-3h9cA:
undetectable		 5icxC-3h9cA:
18.93
5icxF-3h9cA:
2.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UC3_A_486A801_2
(GLUCOCORTICOID
RECEPTOR)		 3h9c METHIONYL-TRNA
SYNTHETASE
(Escherichia
coli) 		4 / 5 LEU A 105
LEU A 108
MET A 308
TYR A 260
 None
 1.21A 5uc3A-3h9cA:
undetectable		 5uc3A-3h9cA:
10.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKU_A_ZMRA901_2
(SIALIDASE)		 3h9c METHIONYL-TRNA
SYNTHETASE
(Escherichia
coli) 		4 / 6 ASP A  83
ASN A 348
LEU A 542
SER A 546
 None
 1.19A 6ekuA-3h9cA:
undetectable		 6ekuA-3h9cA:
19.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_G_TA1G501_1
(TUBULIN BETA CHAIN)		 3h9c METHIONYL-TRNA
SYNTHETASE
(Escherichia
coli) 		5 / 12 LEU A 510
ALA A 393
PHE A 505
LEU A 506
LEU A 408
 None
 1.20A 6ew0G-3h9cA:
undetectable		 6ew0G-3h9cA:
10.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F7L_B_ACTB505_0
(AMINE OXIDASE LKCE)		 3h9c METHIONYL-TRNA
SYNTHETASE
(Escherichia
coli) 		3 / 3 HIS A 349
ASN A 348
LEU A 347
 None
 0.91A 6f7lB-3h9cA:
undetectable		 6f7lB-3h9cA:
21.58