SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3h9m'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D1G_A_MTXA171_1
(DIHYDROFOLATE
REDUCTASE)		 3h9m P-AMINOBENZOATE
SYNTHETASE,
COMPONENT I
(Cytophaga
hutchinsonii) 		5 / 12 ASP A  25
GLU A  17
ILE A  16
LEU A  50
ILE A 140
 None
 1.22A 1d1gA-3h9mA:
undetectable		 1d1gA-3h9mA:
17.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X70_B_715B801_2
(DIPEPTIDYL PEPTIDASE
IV)		 3h9m P-AMINOBENZOATE
SYNTHETASE,
COMPONENT I
(Cytophaga
hutchinsonii) 		3 / 3 PHE A 190
TYR A 411
TYR A 165
 None
 0.98A 1x70B-3h9mA:
undetectable		 1x70B-3h9mA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1H_B_GBNB501_1
(BRANCHED CHAIN
AMINOTRANSFERASE)		 3h9m P-AMINOBENZOATE
SYNTHETASE,
COMPONENT I
(Cytophaga
hutchinsonii) 		4 / 8 VAL A  94
GLY A 364
THR A 365
ALA A  86
 None
 0.88A 2a1hA-3h9mA:
undetectable
2a1hB-3h9mA:
undetectable		 2a1hA-3h9mA:
22.66
2a1hB-3h9mA:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2GLU_B_SAMB302_0
(YCGJ)		 3h9m P-AMINOBENZOATE
SYNTHETASE,
COMPONENT I
(Cytophaga
hutchinsonii) 		5 / 12 GLY A  90
HIS A  98
THR A  99
ALA A  86
PHE A 334
 None
 0.98A 2gluB-3h9mA:
undetectable		 2gluB-3h9mA:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2P_B_DHIB24_0
(INSULIN B CHAIN)		 3h9m P-AMINOBENZOATE
SYNTHETASE,
COMPONENT I
(Cytophaga
hutchinsonii) 		3 / 3 TYR A 217
GLY A 367
PHE A  85
 None
 0.71A 2m2pB-3h9mA:
undetectable		 2m2pB-3h9mA:
7.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AQI_A_CHDA1_0
(FERROCHELATASE)		 3h9m P-AMINOBENZOATE
SYNTHETASE,
COMPONENT I
(Cytophaga
hutchinsonii) 		5 / 11 PHE A  46
ILE A 224
VAL A 329
VAL A  84
TRP A  70
 None
 1.45A 3aqiA-3h9mA:
undetectable		 3aqiA-3h9mA:
19.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_F_SVRF502_2
(PHOSPHOLIPASE A2)		 3h9m P-AMINOBENZOATE
SYNTHETASE,
COMPONENT I
(Cytophaga
hutchinsonii) 		4 / 5 ILE A 381
SER A 228
PRO A 229
PHE A 213
 None
 1.23A 3bjwC-3h9mA:
undetectable		 3bjwC-3h9mA:
15.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LD6_A_KKKA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3h9m P-AMINOBENZOATE
SYNTHETASE,
COMPONENT I
(Cytophaga
hutchinsonii) 		5 / 12 PHE A 394
GLY A 104
ALA A 358
ILE A 351
MET A 339
 None
 1.38A 3ld6A-3h9mA:
undetectable		 3ld6A-3h9mA:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_C_DSFC320_1
(GLR4197 PROTEIN)		 3h9m P-AMINOBENZOATE
SYNTHETASE,
COMPONENT I
(Cytophaga
hutchinsonii) 		4 / 8 TYR A 186
ILE A 401
ILE A 184
ILE A 175
 None
 0.87A 3p4wC-3h9mA:
undetectable		 3p4wC-3h9mA:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RV5_A_DXCA92_0
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 3h9m P-AMINOBENZOATE
SYNTHETASE,
COMPONENT I
(Cytophaga
hutchinsonii) 		4 / 4 LYS A 218
PHE A 219
PHE A  83
VAL A 118
 None
PGE  A 438 (-4.2A)
None
None
 1.18A 3rv5A-3h9mA:
0.0
3rv5B-3h9mA:
0.0		 3rv5A-3h9mA:
13.03
3rv5B-3h9mA:
13.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HDL_A_DXCA75_0
(PPCA)		 3h9m P-AMINOBENZOATE
SYNTHETASE,
COMPONENT I
(Cytophaga
hutchinsonii) 		4 / 8 ILE A 418
ILE A 384
PHE A 394
GLY A 360
 None
 0.97A 4hdlA-3h9mA:
undetectable		 4hdlA-3h9mA:
10.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DPD_A_SAMA601_0
(PROTEIN LYSINE
METHYLTRANSFERASE 1)		 3h9m P-AMINOBENZOATE
SYNTHETASE,
COMPONENT I
(Cytophaga
hutchinsonii) 		5 / 12 GLU A 120
SER A   4
ILE A 128
HIS A  48
VAL A 137
 None
 1.13A 5dpdA-3h9mA:
undetectable		 5dpdA-3h9mA:
24.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MUR_B_PFLB407_1
(PROTON-GATED ION
CHANNEL)		 3h9m P-AMINOBENZOATE
SYNTHETASE,
COMPONENT I
(Cytophaga
hutchinsonii) 		4 / 7 TYR A 186
ILE A 401
ILE A 184
ILE A 175
 None
 0.92A 5murB-3h9mA:
undetectable		 5murB-3h9mA:
10.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2T_A_8LXA501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3h9m P-AMINOBENZOATE
SYNTHETASE,
COMPONENT I
(Cytophaga
hutchinsonii) 		3 / 3 SER A  12
HIS A  48
TYR A  32
 None
 0.69A 5y2tA-3h9mA:
undetectable		 5y2tA-3h9mA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA820_0
(GEPHYRIN)		 3h9m P-AMINOBENZOATE
SYNTHETASE,
COMPONENT I
(Cytophaga
hutchinsonii) 		4 / 5 GLU A 299
PRO A 298
THR A 315
GLN A  43
 None
 1.41A 6fgdA-3h9mA:
undetectable		 6fgdA-3h9mA:
23.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MB5_A_NMYA301_0
(AAC(3)-IIIB PROTEIN)		 3h9m P-AMINOBENZOATE
SYNTHETASE,
COMPONENT I
(Cytophaga
hutchinsonii) 		5 / 11 TYR A 368
ASP A 370
THR A 236
GLY A 237
ASP A 238
 None
 1.19A 6mb5A-3h9mA:
undetectable		 6mb5A-3h9mA:
12.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MB7_A_PARA900_0
(AAC(3)-IIIB PROTEIN)		 3h9m P-AMINOBENZOATE
SYNTHETASE,
COMPONENT I
(Cytophaga
hutchinsonii) 		5 / 10 TYR A 368
ASP A 370
THR A 236
GLY A 237
ASP A 238
 None
 1.16A 6mb7A-3h9mA:
undetectable		 6mb7A-3h9mA:
12.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MB9_A_NMYA303_0
(AAC(3)-IIIB PROTEIN)		 3h9m P-AMINOBENZOATE
SYNTHETASE,
COMPONENT I
(Cytophaga
hutchinsonii) 		5 / 10 TYR A 368
ASP A 370
THR A 236
GLY A 237
ASP A 238
 None
 1.12A 6mb9A-3h9mA:
undetectable		 6mb9A-3h9mA:
12.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MB9_B_NMYB302_0
(AAC(3)-IIIB PROTEIN)		 3h9m P-AMINOBENZOATE
SYNTHETASE,
COMPONENT I
(Cytophaga
hutchinsonii) 		5 / 10 TYR A 368
ASP A 370
THR A 236
GLY A 237
ASP A 238
 None
 1.18A 6mb9B-3h9mA:
undetectable		 6mb9B-3h9mA:
12.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MB9_C_NMYC302_0
(AAC(3)-IIIB PROTEIN)		 3h9m P-AMINOBENZOATE
SYNTHETASE,
COMPONENT I
(Cytophaga
hutchinsonii) 		5 / 10 TYR A 368
ASP A 370
THR A 236
GLY A 237
ASP A 238
 None
 1.14A 6mb9C-3h9mA:
undetectable		 6mb9C-3h9mA:
12.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MB9_D_NMYD302_0
(AAC(3)-IIIB PROTEIN)		 3h9m P-AMINOBENZOATE
SYNTHETASE,
COMPONENT I
(Cytophaga
hutchinsonii) 		5 / 10 TYR A 368
ASP A 370
THR A 236
GLY A 237
ASP A 238
 None
 1.17A 6mb9D-3h9mA:
undetectable		 6mb9D-3h9mA:
12.09