SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3h9p'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Y0X_X_T44X500_1
(THYROID HORMONE
RECEPTOR BETA-1)		 3h9p PUTATIVE
TRIPHOSPHORIBOSYL-DE
PHOSPHO-COA SYNTHASE
(Archaeoglobus
fulgidus) 		5 / 12 ILE A 106
ALA A 107
ARG A 115
ILE A  63
PHE A 268
 None
 1.37A 1y0xX-3h9pA:
undetectable		 1y0xX-3h9pA:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_B_CTXB2_2
(CES1 PROTEIN)		 3h9p PUTATIVE
TRIPHOSPHORIBOSYL-DE
PHOSPHO-COA SYNTHASE
(Archaeoglobus
fulgidus) 		4 / 4 LEU A 160
PRO A 168
ILE A 173
LEU A 177
 None
 0.98A 1ya4B-3h9pA:
undetectable		 1ya4B-3h9pA:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IGT_A_SAMA1001_0
(SAM DEPENDENT
METHYLTRANSFERASE)		 3h9p PUTATIVE
TRIPHOSPHORIBOSYL-DE
PHOSPHO-COA SYNTHASE
(Archaeoglobus
fulgidus) 		5 / 12 PHE A  43
PHE A  85
ALA A  50
ALA A 128
GLY A  64
 None
 1.09A 2igtA-3h9pA:
undetectable		 2igtA-3h9pA:
25.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IGT_B_SAMB1002_0
(SAM DEPENDENT
METHYLTRANSFERASE)		 3h9p PUTATIVE
TRIPHOSPHORIBOSYL-DE
PHOSPHO-COA SYNTHASE
(Archaeoglobus
fulgidus) 		5 / 12 PHE A  43
PHE A  85
ALA A  50
ALA A 128
GLY A  64
 None
 1.08A 2igtB-3h9pA:
undetectable		 2igtB-3h9pA:
25.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IGT_C_SAMC1003_0
(SAM DEPENDENT
METHYLTRANSFERASE)		 3h9p PUTATIVE
TRIPHOSPHORIBOSYL-DE
PHOSPHO-COA SYNTHASE
(Archaeoglobus
fulgidus) 		5 / 12 PHE A  43
PHE A  85
ALA A  50
ALA A 128
GLY A  64
 None
 1.08A 2igtC-3h9pA:
undetectable		 2igtC-3h9pA:
25.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OCF_A_ESTA596_1
(ESTROGEN RECEPTOR)		 3h9p PUTATIVE
TRIPHOSPHORIBOSYL-DE
PHOSPHO-COA SYNTHASE
(Archaeoglobus
fulgidus) 		5 / 10 ALA A 270
GLU A 273
LEU A 192
HIS A 207
LEU A 204
 None
 1.45A 2ocfA-3h9pA:
undetectable		 2ocfA-3h9pA:
24.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PRG_A_BRLA1_2
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 3h9p PUTATIVE
TRIPHOSPHORIBOSYL-DE
PHOSPHO-COA SYNTHASE
(Archaeoglobus
fulgidus) 		3 / 3 ILE A 183
ILE A 259
LEU A 114
 None
 0.56A 2prgA-3h9pA:
undetectable		 2prgA-3h9pA:
24.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD3_A_CHDA502_0
(FERROCHELATASE)		 3h9p PUTATIVE
TRIPHOSPHORIBOSYL-DE
PHOSPHO-COA SYNTHASE
(Archaeoglobus
fulgidus) 		4 / 8 MET A 164
PRO A  93
VAL A  67
GLY A  64
 None
 1.14A 2qd3A-3h9pA:
undetectable		 2qd3A-3h9pA:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2I_A_QPSA1060_1
(ALPHA-1,4-GLUCAN
LYASE ISOZYME 1)		 3h9p PUTATIVE
TRIPHOSPHORIBOSYL-DE
PHOSPHO-COA SYNTHASE
(Archaeoglobus
fulgidus) 		5 / 12 PHE A 181
SER A 184
SER A 266
THR A 263
GLY A  86
 None
 1.20A 2x2iA-3h9pA:
undetectable		 2x2iA-3h9pA:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2I_C_QPSC1060_1
(ALPHA-1,4-GLUCAN
LYASE ISOZYME 1)		 3h9p PUTATIVE
TRIPHOSPHORIBOSYL-DE
PHOSPHO-COA SYNTHASE
(Archaeoglobus
fulgidus) 		5 / 12 PHE A 181
SER A 184
SER A 266
THR A 263
GLY A  86
 None
 1.19A 2x2iC-3h9pA:
undetectable		 2x2iC-3h9pA:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YVL_B_SAMB602_1
(HYPOTHETICAL PROTEIN)		 3h9p PUTATIVE
TRIPHOSPHORIBOSYL-DE
PHOSPHO-COA SYNTHASE
(Archaeoglobus
fulgidus) 		3 / 3 GLU A 244
ASP A 246
TYR A 206
 None
 0.79A 2yvlB-3h9pA:
undetectable		 2yvlB-3h9pA:
24.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL5_B_1UNB201_1
(PROTEASE)		 3h9p PUTATIVE
TRIPHOSPHORIBOSYL-DE
PHOSPHO-COA SYNTHASE
(Archaeoglobus
fulgidus) 		5 / 10 LEU A 269
ALA A 264
GLY A  86
ILE A 173
PRO A  93
 None
 1.13A 3el5A-3h9pA:
undetectable		 3el5A-3h9pA:
19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_2
(GENOME POLYPROTEIN)		 3h9p PUTATIVE
TRIPHOSPHORIBOSYL-DE
PHOSPHO-COA SYNTHASE
(Archaeoglobus
fulgidus) 		3 / 3 PHE A 190
TYR A 206
LEU A 269
 None
 0.78A 3keeB-3h9pA:
undetectable		 3keeB-3h9pA:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9S_A_BEZA264_0
(CARNITINYL-COA
DEHYDRATASE)		 3h9p PUTATIVE
TRIPHOSPHORIBOSYL-DE
PHOSPHO-COA SYNTHASE
(Archaeoglobus
fulgidus) 		5 / 6 ALA A 107
ILE A 185
LEU A 269
GLU A 108
ALA A 100
 None
 1.29A 3r9sA-3h9pA:
undetectable		 3r9sA-3h9pA:
23.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SUE_B_SUEB1201_2
(NS3 PROTEASE, NS4A
PROTEIN)		 3h9p PUTATIVE
TRIPHOSPHORIBOSYL-DE
PHOSPHO-COA SYNTHASE
(Archaeoglobus
fulgidus) 		3 / 3 PHE A 190
TYR A 206
LEU A 269
 None
 0.71A 3sueB-3h9pA:
undetectable		 3sueB-3h9pA:
18.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L3G_F_ACTF401_0
(METHYLAMINE
DEHYDROGENASE HEAVY
CHAIN)		 3h9p PUTATIVE
TRIPHOSPHORIBOSYL-DE
PHOSPHO-COA SYNTHASE
(Archaeoglobus
fulgidus) 		3 / 3 ARG A 175
LEU A 172
GLU A 176
 None
 0.75A 4l3gF-3h9pA:
undetectable		 4l3gF-3h9pA:
21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_C_AERC601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 3h9p PUTATIVE
TRIPHOSPHORIBOSYL-DE
PHOSPHO-COA SYNTHASE
(Archaeoglobus
fulgidus) 		4 / 6 ASP A 121
GLU A 127
VAL A  71
ALA A  70
 None
 0.94A 4nkvC-3h9pA:
undetectable		 4nkvC-3h9pA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_A_STRA601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 3h9p PUTATIVE
TRIPHOSPHORIBOSYL-DE
PHOSPHO-COA SYNTHASE
(Archaeoglobus
fulgidus) 		4 / 6 ASP A 121
GLU A 127
VAL A  71
ALA A  70
 None
 0.90A 4nkxA-3h9pA:
undetectable		 4nkxA-3h9pA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_R_BEZR801_1
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 3h9p PUTATIVE
TRIPHOSPHORIBOSYL-DE
PHOSPHO-COA SYNTHASE
(Archaeoglobus
fulgidus) 		4 / 8 PHE A 268
SER A 184
LEU A  90
LEU A  91
 None
 1.07A 5dzkd-3h9pA:
undetectable
5dzkr-3h9pA:
undetectable		 5dzkd-3h9pA:
23.62
5dzkr-3h9pA:
1.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_S_BEZS801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 3h9p PUTATIVE
TRIPHOSPHORIBOSYL-DE
PHOSPHO-COA SYNTHASE
(Archaeoglobus
fulgidus) 		4 / 6 PHE A 268
SER A 184
LEU A  90
LEU A  91
 None
 1.18A 5dzke-3h9pA:
undetectable
5dzks-3h9pA:
undetectable		 5dzke-3h9pA:
23.62
5dzks-3h9pA:
1.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GS4_A_ESTA603_2
(ESTROGEN RECEPTOR)		 3h9p PUTATIVE
TRIPHOSPHORIBOSYL-DE
PHOSPHO-COA SYNTHASE
(Archaeoglobus
fulgidus) 		4 / 6 LEU A 262
LEU A  94
LEU A  91
LEU A 177
 None
 0.80A 5gs4A-3h9pA:
undetectable		 5gs4A-3h9pA:
20.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NFJ_A_SAMA501_0
(MITOCHONDRIAL
RIBONUCLEASE P
PROTEIN 1)		 3h9p PUTATIVE
TRIPHOSPHORIBOSYL-DE
PHOSPHO-COA SYNTHASE
(Archaeoglobus
fulgidus) 		5 / 12 LEU A 262
THR A 263
ALA A 264
GLY A 187
LEU A  90
 None
 0.96A 5nfjA-3h9pA:
undetectable		 5nfjA-3h9pA:
23.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X5Q_C_D16C402_1
(THYMIDYLATE SYNTHASE)		 3h9p PUTATIVE
TRIPHOSPHORIBOSYL-DE
PHOSPHO-COA SYNTHASE
(Archaeoglobus
fulgidus) 		4 / 7 PHE A  85
ILE A 173
LEU A 216
GLY A 257
 None
 0.82A 5x5qC-3h9pA:
undetectable		 5x5qC-3h9pA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X5Q_D_D16D402_1
(THYMIDYLATE SYNTHASE)		 3h9p PUTATIVE
TRIPHOSPHORIBOSYL-DE
PHOSPHO-COA SYNTHASE
(Archaeoglobus
fulgidus) 		4 / 8 PHE A  85
ILE A 173
LEU A 216
GLY A 257
 None
 0.79A 5x5qD-3h9pA:
undetectable		 5x5qD-3h9pA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X5Q_E_D16E402_1
(THYMIDYLATE SYNTHASE)		 3h9p PUTATIVE
TRIPHOSPHORIBOSYL-DE
PHOSPHO-COA SYNTHASE
(Archaeoglobus
fulgidus) 		4 / 6 PHE A  85
ILE A 173
LEU A 216
GLY A 257
 None
 0.79A 5x5qE-3h9pA:
undetectable		 5x5qE-3h9pA:
21.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X5Q_F_D16F402_1
(THYMIDYLATE SYNTHASE)		 3h9p PUTATIVE
TRIPHOSPHORIBOSYL-DE
PHOSPHO-COA SYNTHASE
(Archaeoglobus
fulgidus) 		4 / 8 PHE A  85
ILE A 173
LEU A 216
GLY A 257
 None
 0.81A 5x5qF-3h9pA:
undetectable		 5x5qF-3h9pA:
21.25