SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3ha2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BR4_E_SAME301_0
(CEPHALOSPORIN
HYDROXYLASE CMCI)		 3ha2 NADPH-QUINONE
REDUCTASE
(Pediococcus
pentosaceus) 		5 / 12 LEU A  61
GLY A 105
ASP A 103
ALA A 107
ALA A 112
 None
 1.16A 2br4E-3ha2A:
undetectable		 2br4E-3ha2A:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F78_A_BEZA1003_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 3ha2 NADPH-QUINONE
REDUCTASE
(Pediococcus
pentosaceus) 		4 / 7 SER A 100
LEU A  12
PHE A  21
THR A  17
 None
None
None
SO4  A 178 (-2.9A)
 1.07A 2f78A-3ha2A:
undetectable		 2f78A-3ha2A:
23.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F78_B_BEZB1004_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR BENM)		 3ha2 NADPH-QUINONE
REDUCTASE
(Pediococcus
pentosaceus) 		4 / 7 SER A 100
LEU A  12
PHE A  21
THR A  17
 None
None
None
SO4  A 178 (-2.9A)
 1.02A 2f78B-3ha2A:
undetectable		 2f78B-3ha2A:
23.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QKN_A_JMSA602_1
(ALPHA-KETOGLUTARATE-
DEPENDENT
DIOXYGENASE FTO)		 3ha2 NADPH-QUINONE
REDUCTASE
(Pediococcus
pentosaceus) 		4 / 8 LEU A 146
LEU A 148
SER A 100
HIS A 143
 None
 1.19A 4qknA-3ha2A:
undetectable		 4qknA-3ha2A:
17.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECM_A_LEUA602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 3ha2 NADPH-QUINONE
REDUCTASE
(Pediococcus
pentosaceus) 		4 / 5 THR A  80
ALA A  83
THR A  84
TYR A  88
 SO4  A 179 (-4.0A)
None
None
None
 1.22A 5ecmA-3ha2A:
2.2		 5ecmA-3ha2A:
15.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DIF_B_TPVB201_0
(HIV-1 PROTEASE)		 3ha2 NADPH-QUINONE
REDUCTASE
(Pediococcus
pentosaceus) 		5 / 12 ALA A 164
GLY A  96
ILE A  97
VAL A   7
ILE A   5
 None
 1.22A 6difA-3ha2A:
undetectable		 6difA-3ha2A:
18.93