SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3hag'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A7Y_B_DVAB2_0
(ACTINOMYCIN D)		 3hag CAPSID PROTEIN
(Orthohepevirus
A) 		3 / 3 THR A 217
PRO A 219
THR A 218
 None
 0.83A 1a7yB-3hagA:
undetectable		 1a7yB-3hagA:
2.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GMK_A_DVAA6_0
(GRAMICIDIN A)		 3hag CAPSID PROTEIN
(Orthohepevirus
A) 		3 / 3 ALA A 507
VAL A 503
TRP A 472
 None
 0.97A 1gmkA-3hagA:
undetectable
1gmkB-3hagA:
undetectable		 1gmkA-3hagA:
3.21
1gmkB-3hagA:
3.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HXB_A_ROCA100_2
(HIV-1 PROTEASE)		 3hag CAPSID PROTEIN
(Orthohepevirus
A) 		3 / 3 ARG A 460
THR A 520
VAL A 464
 None
 0.76A 1hxbA-3hagA:
undetectable		 1hxbA-3hagA:
10.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QKN_A_RALA600_2
(ESTROGEN RECEPTOR
BETA)		 3hag CAPSID PROTEIN
(Orthohepevirus
A) 		3 / 3 ASP A 515
LEU A 514
HIS A 604
 None
 0.53A 1qknA-3hagA:
undetectable		 1qknA-3hagA:
20.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TV8_B_SAMB2501_0
(MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
A)		 3hag CAPSID PROTEIN
(Orthohepevirus
A) 		4 / 7 TYR A 323
THR A 144
THR A 146
SER A 326
 None
 1.21A 1tv8B-3hagA:
undetectable		 1tv8B-3hagA:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_F_DVAF2_0
(7-AMINO-ACTINOMYCIN
D)		 3hag CAPSID PROTEIN
(Orthohepevirus
A) 		3 / 3 THR A 217
PRO A 219
THR A 218
 None
 0.86A 1unjF-3hagA:
undetectable		 1unjF-3hagA:
2.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_R_DVAR2_0
(7-AMINO-ACTINOMYCIN
D)		 3hag CAPSID PROTEIN
(Orthohepevirus
A) 		3 / 3 THR A 217
PRO A 219
THR A 218
 None
 0.87A 1unjR-3hagA:
undetectable		 1unjR-3hagA:
2.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UPF_A_URFA999_1
(URACIL
PHOSPHORIBOSYLTRANSF
ERASE)		 3hag CAPSID PROTEIN
(Orthohepevirus
A) 		4 / 5 ALA A 339
TYR A 413
ILE A 425
ASP A 422
 None
 1.13A 1upfA-3hagA:
undetectable		 1upfA-3hagA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UPF_C_URFC999_1
(URACIL
PHOSPHORIBOSYLTRANSF
ERASE)		 3hag CAPSID PROTEIN
(Orthohepevirus
A) 		4 / 5 ALA A 339
TYR A 413
ILE A 425
ASP A 422
 None
 1.04A 1upfC-3hagA:
undetectable		 1upfC-3hagA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QAK_A_1UNA1001_2
(PROTEASE RETROPEPSIN)		 3hag CAPSID PROTEIN
(Orthohepevirus
A) 		3 / 3 ARG A 460
THR A 520
VAL A 464
 None
 0.77A 2qakA-3hagA:
undetectable		 2qakA-3hagA:
11.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XKK_E_MFXE1100_1
(TOPOISOMERASE IV
DNA)		 3hag CAPSID PROTEIN
(Orthohepevirus
A) 		3 / 3 ARG A 259
GLU A 417
SER A 161
 None
 0.90A 2xkkA-3hagA:
undetectable
2xkkC-3hagA:
undetectable		 2xkkA-3hagA:
20.43
2xkkC-3hagA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CFL_A_5CHA693_1
(LACTOTRANSFERRIN)		 3hag CAPSID PROTEIN
(Orthohepevirus
A) 		4 / 4 THR A 144
VAL A 439
GLY A 169
THR A 170
 None
 1.10A 3cflA-3hagA:
undetectable		 3cflA-3hagA:
19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OND_A_ADNA506_2
(ADENOSYLHOMOCYSTEINA
SE)		 3hag CAPSID PROTEIN
(Orthohepevirus
A) 		3 / 3 GLN A 214
THR A 215
LEU A 251
 None
 0.69A 3ondA-3hagA:
undetectable		 3ondA-3hagA:
22.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_A_ACTA502_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 3hag CAPSID PROTEIN
(Orthohepevirus
A) 		4 / 5 TYR A 194
VAL A 236
SER A 242
GLY A 239
 None
 1.08A 3v4tA-3hagA:
undetectable
3v4tD-3hagA:
undetectable		 3v4tA-3hagA:
21.89
3v4tD-3hagA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACA_C_DXCC1475_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 3hag CAPSID PROTEIN
(Orthohepevirus
A) 		4 / 8 ILE A 280
ILE A 207
VAL A 198
GLY A 239
 None
 0.82A 4acaC-3hagA:
undetectable		 4acaC-3hagA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B7N_A_ZMRA601_2
(NEURAMINIDASE)		 3hag CAPSID PROTEIN
(Orthohepevirus
A) 		3 / 3 ARG A 186
ARG A 259
TRP A 258
 None
 1.44A 4b7nA-3hagA:
undetectable		 4b7nA-3hagA:
23.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_C_ZMRC1470_2
(NEURAMINIDASE)		 3hag CAPSID PROTEIN
(Orthohepevirus
A) 		3 / 3 ARG A 186
ARG A 259
TRP A 258
 None
 1.44A 4cpzC-3hagA:
undetectable		 4cpzC-3hagA:
23.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_F_ZMRF1470_2
(NEURAMINIDASE)		 3hag CAPSID PROTEIN
(Orthohepevirus
A) 		3 / 3 ARG A 186
ARG A 259
TRP A 258
 None
 1.41A 4cpzF-3hagA:
undetectable		 4cpzF-3hagA:
23.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_H_ZMRH1470_2
(NEURAMINIDASE)		 3hag CAPSID PROTEIN
(Orthohepevirus
A) 		3 / 3 ARG A 186
ARG A 259
TRP A 258
 None
 1.40A 4cpzH-3hagA:
undetectable		 4cpzH-3hagA:
23.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQB_B_017B101_2
(ASPARTYL PROTEASE)		 3hag CAPSID PROTEIN
(Orthohepevirus
A) 		5 / 10 ALA A 419
VAL A 364
GLY A 424
ILE A 425
VAL A 410
 None
 0.93A 4dqbB-3hagA:
undetectable		 4dqbB-3hagA:
11.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQE_B_017B101_2
(ASPARTYL PROTEASE)		 3hag CAPSID PROTEIN
(Orthohepevirus
A) 		5 / 10 ALA A 419
VAL A 364
GLY A 424
ILE A 425
VAL A 410
 None
 0.95A 4dqeB-3hagA:
undetectable		 4dqeB-3hagA:
11.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQH_B_017B101_2
(WILD-TYPE HIV-1
PROTEASE DIMER)		 3hag CAPSID PROTEIN
(Orthohepevirus
A) 		5 / 10 ALA A 419
VAL A 364
GLY A 424
ILE A 425
VAL A 410
 None
 0.97A 4dqhB-3hagA:
undetectable		 4dqhB-3hagA:
13.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGZ_A_CQAA302_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE)		 3hag CAPSID PROTEIN
(Orthohepevirus
A) 		4 / 7 GLU A 307
TYR A 185
GLY A 257
ARG A 186
 None
 1.01A 4fgzA-3hagA:
undetectable		 4fgzA-3hagA:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KY8_A_MTXA603_1
(BIFUNCTIONAL
THYMIDYLATE
SYNTHASE-DIHYDROFOLA
TE REDUCTASE)		 3hag CAPSID PROTEIN
(Orthohepevirus
A) 		5 / 12 ALA A 507
LEU A 465
ILE A 569
LEU A 541
THR A 505
 None
 1.12A 4ky8A-3hagA:
undetectable		 4ky8A-3hagA:
22.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KY8_D_MTXD603_1
(BIFUNCTIONAL
THYMIDYLATE
SYNTHASE-DIHYDROFOLA
TE REDUCTASE)		 3hag CAPSID PROTEIN
(Orthohepevirus
A) 		5 / 12 ALA A 507
LEU A 465
ILE A 569
LEU A 541
THR A 505
 None
 1.11A 4ky8D-3hagA:
undetectable		 4ky8D-3hagA:
22.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LG1_C_SAMC301_0
(PROTEIN-LYSINE
METHYLTRANSFERASE
METTL21D)		 3hag CAPSID PROTEIN
(Orthohepevirus
A) 		5 / 12 GLY A 367
GLY A 365
ASP A 352
LEU A 353
ALA A 419
 None
 1.12A 4lg1C-3hagA:
undetectable		 4lg1C-3hagA:
18.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KVA_A_SAMA301_1
(CAFFEOYL-COA
O-METHYLTRANSFERASE)		 3hag CAPSID PROTEIN
(Orthohepevirus
A) 		3 / 3 THR A 146
SER A 326
ASP A 168
 None
 0.77A 5kvaA-3hagA:
undetectable		 5kvaA-3hagA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KVA_B_SAMB301_1
(CAFFEOYL-COA
O-METHYLTRANSFERASE)		 3hag CAPSID PROTEIN
(Orthohepevirus
A) 		3 / 3 THR A 146
SER A 326
ASP A 168
 None
 0.79A 5kvaB-3hagA:
undetectable		 5kvaB-3hagA:
20.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LAK_I_BEZI1_0
(3CL PROTEASE
BEZ-TYR-TYR-ASN-ECC
PEPTIDE INHIBITOR)		 3hag CAPSID PROTEIN
(Orthohepevirus
A) 		3 / 3 SER A 398
TYR A 397
TYR A 413
 None
 0.80A 5lakA-3hagA:
undetectable
5lakI-3hagA:
undetectable		 5lakA-3hagA:
21.28
5lakI-3hagA:
2.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LAK_J_BEZJ1_0
(3CL PROTEASE
BEZ-TYR-TYR-ASN-ECC
PEPTIDE INHIBITOR)		 3hag CAPSID PROTEIN
(Orthohepevirus
A) 		3 / 3 SER A 398
TYR A 397
TYR A 413
 None
 0.89A 5lakC-3hagA:
undetectable
5lakJ-3hagA:
undetectable		 5lakC-3hagA:
21.28
5lakJ-3hagA:
2.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TWJ_D_SAMD201_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE H)		 3hag CAPSID PROTEIN
(Orthohepevirus
A) 		5 / 11 ASP A 430
GLY A 334
LEU A 433
THR A 342
LEU A 341
 None
 0.84A 5twjD-3hagA:
undetectable		 5twjD-3hagA:
14.54