SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3hbd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSS_G_CCSG149_0
(D-GLYCERALDEHYDE-3-P
HOSPHATE-DEHYDROGENA
SE)		 3hbd CLASS IV CHITINASE
CHIA4-PA2
(Picea
abies) 		4 / 7 SER A 153
TYR A 156
ASN A 155
TYR A 158
 ACT  A 310 (-3.2A)
None
None
None
 0.99A 1dssG-3hbdA:
undetectable		 1dssG-3hbdA:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSS_R_CCSR149_0
(D-GLYCERALDEHYDE-3-P
HOSPHATE-DEHYDROGENA
SE)		 3hbd CLASS IV CHITINASE
CHIA4-PA2
(Picea
abies) 		4 / 8 SER A 153
TYR A 156
ASN A 155
TYR A 158
 ACT  A 310 (-3.2A)
None
None
None
 0.99A 1dssR-3hbdA:
undetectable		 1dssR-3hbdA:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RQP_B_SAMB500_1
(5'-FLUORO-5'-DEOXYAD
ENOSINE SYNTHASE)		 3hbd CLASS IV CHITINASE
CHIA4-PA2
(Picea
abies) 		4 / 8 ASN A 109
PHE A 207
SER A 229
ALA A 105
 None
 1.17A 1rqpC-3hbdA:
undetectable		 1rqpC-3hbdA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RQP_C_SAMC500_0
(5'-FLUORO-5'-DEOXYAD
ENOSINE SYNTHASE)		 3hbd CLASS IV CHITINASE
CHIA4-PA2
(Picea
abies) 		4 / 8 ASN A 109
PHE A 207
SER A 229
ALA A 105
 None
 1.14A 1rqpA-3hbdA:
undetectable		 1rqpA-3hbdA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9C_A_ACTA1121_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 3hbd CLASS IV CHITINASE
CHIA4-PA2
(Picea
abies) 		4 / 5 SER A 250
VAL A 227
VAL A 249
SER A 228
 None
 1.19A 2j9cA-3hbdA:
undetectable
2j9cB-3hbdA:
undetectable
2j9cC-3hbdA:
undetectable		 2j9cA-3hbdA:
19.81
2j9cB-3hbdA:
19.81
2j9cC-3hbdA:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V7U_A_SAMA1299_0
(5'-FLUORO-5'-DEOXY
ADENOSINE SYNTHETASE)		 3hbd CLASS IV CHITINASE
CHIA4-PA2
(Picea
abies) 		4 / 8 ASN A 109
PHE A 207
SER A 229
ALA A 105
 None
 1.10A 2v7uA-3hbdA:
undetectable		 2v7uA-3hbdA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WX2_A_TPFA1460_1
(LANOSTEROL
14-ALPHA-DEMETHYLASE)		 3hbd CLASS IV CHITINASE
CHIA4-PA2
(Picea
abies) 		4 / 7 TYR A  77
ALA A  82
ALA A  84
LEU A 103
 None
 0.96A 2wx2A-3hbdA:
undetectable		 2wx2A-3hbdA:
19.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DMT_C_CCSC166_0
(GLYCERALDEHYDE-3-PHO
SPHATE
DEHYDROGENASE,
GLYCOSOMAL)		 3hbd CLASS IV CHITINASE
CHIA4-PA2
(Picea
abies) 		4 / 8 SER A 153
TYR A 156
ASN A 155
TYR A 158
 ACT  A 310 (-3.2A)
None
None
None
 1.01A 3dmtC-3hbdA:
undetectable		 3dmtC-3hbdA:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SOA_A_DB8A445_1
(CALCIUM/CALMODULIN-D
EPENDENT PROTEIN
KINASE TYPE II
SUBUNIT ALPHA WITH A
BETA 7 LINKER)		 3hbd CLASS IV CHITINASE
CHIA4-PA2
(Picea
abies) 		4 / 6 LEU A 150
VAL A 110
VAL A 188
PHE A  58
 None
 1.09A 3soaA-3hbdA:
undetectable		 3soaA-3hbdA:
15.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VNS_A_DVAA602_0
(NRPS ADENYLATION
PROTEIN CYTC1)		 3hbd CLASS IV CHITINASE
CHIA4-PA2
(Picea
abies) 		4 / 7 PHE A 184
PHE A  80
THR A 186
PHE A  90
 None
 1.11A 3vnsA-3hbdA:
undetectable		 3vnsA-3hbdA:
15.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F93_B_SANB3004_1
(U5 SMALL NUCLEAR
RIBONUCLEOPROTEIN
200 KDA HELICASE)		 3hbd CLASS IV CHITINASE
CHIA4-PA2
(Picea
abies) 		4 / 8 TRP A 191
GLN A 205
GLY A 204
SER A 203
 None
 0.86A 4f93B-3hbdA:
undetectable		 4f93B-3hbdA:
7.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_B_ADNB402_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3hbd CLASS IV CHITINASE
CHIA4-PA2
(Picea
abies) 		5 / 9 GLU A 102
ILE A  52
VAL A  49
CYH A 238
ILE A  53
 None
 1.08A 4lbgB-3hbdA:
undetectable		 4lbgB-3hbdA:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVV_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3hbd CLASS IV CHITINASE
CHIA4-PA2
(Picea
abies) 		4 / 8 LYS A  99
GLY A  51
GLY A  50
VAL A  49
 None
 0.82A 4qvvK-3hbdA:
undetectable
4qvvL-3hbdA:
undetectable		 4qvvK-3hbdA:
22.45
4qvvL-3hbdA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVV_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 3hbd CLASS IV CHITINASE
CHIA4-PA2
(Picea
abies) 		4 / 8 LYS A  99
GLY A  51
GLY A  50
VAL A  49
 None
 0.82A 4qvvY-3hbdA:
undetectable
4qvvZ-3hbdA:
undetectable		 4qvvY-3hbdA:
22.45
4qvvZ-3hbdA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WMZ_A_TPFA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3hbd CLASS IV CHITINASE
CHIA4-PA2
(Picea
abies) 		5 / 9 PHE A  80
ILE A  81
TYR A  77
PHE A 107
LEU A 241
 None
 1.47A 4wmzA-3hbdA:
undetectable		 4wmzA-3hbdA:
16.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y03_B_SALB801_1
(PROTEIN POLYBROMO-1)		 3hbd CLASS IV CHITINASE
CHIA4-PA2
(Picea
abies) 		4 / 5 LEU A 103
ALA A  84
ASN A  85
ILE A  81
 None
 1.14A 4y03B-3hbdA:
2.2		 4y03B-3hbdA:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESF_A_TPFA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 3hbd CLASS IV CHITINASE
CHIA4-PA2
(Picea
abies) 		5 / 8 PHE A  80
ILE A  81
TYR A  77
PHE A 107
LEU A 241
 None
 1.40A 5esfA-3hbdA:
undetectable		 5esfA-3hbdA:
17.52