SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3hbn'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XLX_B_CIOB102_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4B)		 3hbn UDP-SUGAR HYDROLASE
(Campylobacter
jejuni) 		5 / 12 HIS A 281
HIS A 280
THR A 167
ILE A 169
SER A  10
 None
 1.43A 1xlxB-3hbnA:
undetectable		 1xlxB-3hbnA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FBX_A_ACTA608_0
(PUTATIVE
PHOSPHOLIPASE B-LIKE
2)		 3hbn UDP-SUGAR HYDROLASE
(Campylobacter
jejuni) 		3 / 3 GLU A 257
VAL A 253
CYH A 251
 None
 0.82A 3fbxA-3hbnA:
undetectable		 3fbxA-3hbnA:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7B_B_HAEB1270_1
(COLLAGENASE 3)		 3hbn UDP-SUGAR HYDROLASE
(Campylobacter
jejuni) 		4 / 5 LEU A 172
HIS A 279
HIS A 281
HIS A 280
 None
 1.32A 4a7bB-3hbnA:
undetectable		 4a7bB-3hbnA:
17.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OM3_B_DXTB501_1
(ALPHA-1-ANTICHYMOTRY
PSIN)		 3hbn UDP-SUGAR HYDROLASE
(Campylobacter
jejuni) 		4 / 6 LEU A  97
PHE A  99
ASP A 100
HIS A  17
 None
None
None
GOL  A 302 (-3.0A)
 1.20A 5om3A-3hbnA:
undetectable
5om3B-3hbnA:
undetectable		 5om3A-3hbnA:
14.89
5om3B-3hbnA:
11.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OM3_B_DXTB501_1
(ALPHA-1-ANTICHYMOTRY
PSIN)		 3hbn UDP-SUGAR HYDROLASE
(Campylobacter
jejuni) 		4 / 6 LEU A  97
SER A  98
PHE A  99
HIS A  17
 None
None
None
GOL  A 302 (-3.0A)
 0.95A 5om3A-3hbnA:
undetectable
5om3B-3hbnA:
undetectable		 5om3A-3hbnA:
14.89
5om3B-3hbnA:
11.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOO_E_C2FE3001_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 3hbn UDP-SUGAR HYDROLASE
(Campylobacter
jejuni) 		5 / 12 GLU A  85
ASP A  84
LEU A  53
SER A  98
ILE A  80
 None
 1.17A 5vooE-3hbnA:
2.1		 5vooE-3hbnA:
23.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VOO_F_C2FF3001_0
(5-METHYLTETRAHYDROFO
LATE HOMOCYSTEINE
S-METHYLTRANSFERASE)		 3hbn UDP-SUGAR HYDROLASE
(Campylobacter
jejuni) 		5 / 12 GLU A  85
ASP A  84
LEU A  53
SER A  98
ILE A  80
 None
 1.16A 5vooF-3hbnA:
4.7		 5vooF-3hbnA:
23.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AYB_A_KKKA508_1
(CYP51, STEROL
14ALPHA-DEMETHYLASE)		 3hbn UDP-SUGAR HYDROLASE
(Campylobacter
jejuni) 		5 / 12 TYR A 117
ALA A 260
ALA A 233
ILE A 142
LEU A 241
 None
 1.11A 6aybA-3hbnA:
undetectable		 6aybA-3hbnA:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_A_AQ4A602_0
(CYTOCHROME P450 1A1)		 3hbn UDP-SUGAR HYDROLASE
(Campylobacter
jejuni) 		5 / 12 SER A 173
ASP A 168
GLY A 166
PHE A  15
ILE A 188
 None
None
UDP  A 301 (-3.5A)
None
None
 1.04A 6dwnA-3hbnA:
undetectable		 6dwnA-3hbnA:
10.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_C_AQ4C602_0
(CYTOCHROME P450 1A1)		 3hbn UDP-SUGAR HYDROLASE
(Campylobacter
jejuni) 		5 / 12 SER A 173
ASP A 168
GLY A 166
PHE A  15
ILE A 188
 None
None
UDP  A 301 (-3.5A)
None
None
 1.07A 6dwnC-3hbnA:
undetectable		 6dwnC-3hbnA:
10.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_D_AQ4D602_0
(CYTOCHROME P450 1A1)		 3hbn UDP-SUGAR HYDROLASE
(Campylobacter
jejuni) 		5 / 12 SER A 173
ASP A 168
GLY A 166
PHE A  15
ILE A 188
 None
None
UDP  A 301 (-3.5A)
None
None
 1.08A 6dwnD-3hbnA:
undetectable		 6dwnD-3hbnA:
10.49