SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3hbz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NW5_A_SAMA401_1
(MODIFICATION
METHYLASE RSRI)		 3hbz PUTATIVE GLYCOSIDE
HYDROLASE
(Bacteroides
thetaiotaomicron) 		3 / 3 ASP A  61
HIS A  88
ASP A 112
 None
 0.87A 1nw5A-3hbzA:
undetectable		 1nw5A-3hbzA:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FL9_D_TOPD200_1
(DIHYDROFOLATE
REDUCTASE (DHFR))		 3hbz PUTATIVE GLYCOSIDE
HYDROLASE
(Bacteroides
thetaiotaomicron) 		5 / 9 LEU A 348
VAL A 353
ILE A 291
LEU A 305
PHE A 303
 None
 1.34A 3fl9D-3hbzA:
undetectable		 3fl9D-3hbzA:
16.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_O_TFPO201_1
(PROTEIN S100-A4)		 3hbz PUTATIVE GLYCOSIDE
HYDROLASE
(Bacteroides
thetaiotaomicron) 		4 / 8 GLY A 345
CYH A 177
PHE A 133
GLY A 199
 None
 0.87A 3ko0O-3hbzA:
undetectable
3ko0Q-3hbzA:
undetectable		 3ko0O-3hbzA:
14.96
3ko0Q-3hbzA:
14.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_P_TFPP201_1
(PROTEIN S100-A4)		 3hbz PUTATIVE GLYCOSIDE
HYDROLASE
(Bacteroides
thetaiotaomicron) 		4 / 7 GLY A 199
GLY A 345
CYH A 177
PHE A 133
 None
 0.84A 3ko0M-3hbzA:
undetectable
3ko0P-3hbzA:
undetectable		 3ko0M-3hbzA:
14.96
3ko0P-3hbzA:
14.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_T_TFPT201_1
(PROTEIN S100-A4)		 3hbz PUTATIVE GLYCOSIDE
HYDROLASE
(Bacteroides
thetaiotaomicron) 		4 / 7 PHE A 167
GLY A 345
CYH A 177
PHE A 133
 None
 1.11A 3ko0R-3hbzA:
undetectable
3ko0T-3hbzA:
undetectable		 3ko0R-3hbzA:
14.96
3ko0T-3hbzA:
14.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_G_PZIG800_0
(GLUTAMATE RECEPTOR 2)		 3hbz PUTATIVE GLYCOSIDE
HYDROLASE
(Bacteroides
thetaiotaomicron) 		4 / 6 ASN A 278
LEU A 274
ASP A 275
LYS A 220
 None
None
None
P6G  A 362 (-3.0A)
 1.44A 3lslG-3hbzA:
undetectable		 3lslG-3hbzA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3S_C_9PLC1_1
(CYTOCHROME P450 2A13)		 3hbz PUTATIVE GLYCOSIDE
HYDROLASE
(Bacteroides
thetaiotaomicron) 		4 / 7 PHE A 307
ASN A 326
ALA A 328
LEU A 355
 None
 1.11A 3t3sC-3hbzA:
undetectable		 3t3sC-3hbzA:
22.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_D_CLMD221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3hbz PUTATIVE GLYCOSIDE
HYDROLASE
(Bacteroides
thetaiotaomicron) 		5 / 12 THR A 332
TYR A 261
LEU A 216
PHE A 221
ALA A 279
 None
 1.37A 3u9fD-3hbzA:
undetectable
3u9fE-3hbzA:
undetectable		 3u9fD-3hbzA:
21.71
3u9fE-3hbzA:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UBO_B_ADNB353_1
(ADENOSINE KINASE)		 3hbz PUTATIVE GLYCOSIDE
HYDROLASE
(Bacteroides
thetaiotaomicron) 		5 / 12 ILE A 203
GLY A 204
GLY A 222
LEU A 355
THR A  43
 None
 0.85A 3uboB-3hbzA:
undetectable		 3uboB-3hbzA:
20.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V81_A_NVPA901_1
(HIV-1 REVERSE
TRANSCRIPTASE P66
SUBUNIT)		 3hbz PUTATIVE GLYCOSIDE
HYDROLASE
(Bacteroides
thetaiotaomicron) 		4 / 8 LYS A 173
TYR A 119
TRP A 145
LEU A 178
 None
 1.06A 3v81A-3hbzA:
undetectable		 3v81A-3hbzA:
21.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VT7_A_VDXA500_2
(VITAMIN D3 RECEPTOR)		 3hbz PUTATIVE GLYCOSIDE
HYDROLASE
(Bacteroides
thetaiotaomicron) 		4 / 4 LEU A 320
ILE A 203
TYR A 265
TYR A 357
 None
 1.27A 3vt7A-3hbzA:
undetectable		 3vt7A-3hbzA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AT0_A_ACTA1490_0
(3-KETOSTEROID-DELTA4
-5ALPHA-DEHYDROGENAS
E)		 3hbz PUTATIVE GLYCOSIDE
HYDROLASE
(Bacteroides
thetaiotaomicron) 		3 / 3 GLU A 296
TYR A 238
SER A 346
 None
 1.00A 4at0A-3hbzA:
undetectable		 4at0A-3hbzA:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3A_A_ADNA500_1
(SUGAR KINASE PROTEIN)		 3hbz PUTATIVE GLYCOSIDE
HYDROLASE
(Bacteroides
thetaiotaomicron) 		5 / 12 ILE A 203
GLY A 204
GLY A 222
LEU A 355
THR A  43
 None
 0.87A 4e3aA-3hbzA:
undetectable		 4e3aA-3hbzA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKU_B_ADNB500_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3hbz PUTATIVE GLYCOSIDE
HYDROLASE
(Bacteroides
thetaiotaomicron) 		5 / 12 ILE A 203
GLY A 204
GLY A 222
LEU A 355
THR A  43
 None
 0.84A 4jkuB-3hbzA:
undetectable		 4jkuB-3hbzA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K7A_A_MXDA1002_1
(ANDROGEN RECEPTOR)		 3hbz PUTATIVE GLYCOSIDE
HYDROLASE
(Bacteroides
thetaiotaomicron) 		3 / 3 GLU A  28
TRP A 102
LYS A 105
 CA  A   2 ( 3.1A)
CAC  A   5 (-4.7A)
None
 1.03A 4k7aA-3hbzA:
undetectable		 4k7aA-3hbzA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8P_A_ADNA401_1
(SUGAR KINASE)		 3hbz PUTATIVE GLYCOSIDE
HYDROLASE
(Bacteroides
thetaiotaomicron) 		5 / 12 ILE A 203
GLY A 204
GLY A 222
LEU A 355
THR A  43
 None
 0.85A 4k8pA-3hbzA:
undetectable		 4k8pA-3hbzA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8P_B_ADNB401_1
(SUGAR KINASE)		 3hbz PUTATIVE GLYCOSIDE
HYDROLASE
(Bacteroides
thetaiotaomicron) 		5 / 12 ILE A 203
GLY A 204
GLY A 222
LEU A 355
THR A  43
 None
 0.85A 4k8pB-3hbzA:
undetectable		 4k8pB-3hbzA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8T_A_ADNA401_1
(SUGAR KINASE)		 3hbz PUTATIVE GLYCOSIDE
HYDROLASE
(Bacteroides
thetaiotaomicron) 		5 / 12 ILE A 203
GLY A 204
GLY A 222
LEU A 355
THR A  43
 None
 0.83A 4k8tA-3hbzA:
undetectable		 4k8tA-3hbzA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8T_B_ADNB401_1
(SUGAR KINASE)		 3hbz PUTATIVE GLYCOSIDE
HYDROLASE
(Bacteroides
thetaiotaomicron) 		5 / 12 ILE A 203
GLY A 204
GLY A 222
LEU A 355
THR A  43
 None
 0.85A 4k8tB-3hbzA:
undetectable		 4k8tB-3hbzA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K93_A_ADNA401_1
(SUGAR KINASE)		 3hbz PUTATIVE GLYCOSIDE
HYDROLASE
(Bacteroides
thetaiotaomicron) 		5 / 12 ILE A 203
GLY A 204
GLY A 222
LEU A 355
THR A  43
 None
 0.86A 4k93A-3hbzA:
undetectable		 4k93A-3hbzA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K93_B_ADNB402_1
(SUGAR KINASE)		 3hbz PUTATIVE GLYCOSIDE
HYDROLASE
(Bacteroides
thetaiotaomicron) 		5 / 12 ILE A 203
GLY A 204
GLY A 222
LEU A 355
THR A  43
 None
 0.85A 4k93B-3hbzA:
undetectable		 4k93B-3hbzA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9C_A_ADNA401_1
(SUGAR KINASE)		 3hbz PUTATIVE GLYCOSIDE
HYDROLASE
(Bacteroides
thetaiotaomicron) 		5 / 12 ILE A 203
GLY A 204
GLY A 222
LEU A 355
THR A  43
 None
 0.85A 4k9cA-3hbzA:
undetectable		 4k9cA-3hbzA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9C_B_ADNB401_1
(SUGAR KINASE)		 3hbz PUTATIVE GLYCOSIDE
HYDROLASE
(Bacteroides
thetaiotaomicron) 		5 / 12 ILE A 203
GLY A 204
GLY A 222
LEU A 355
THR A  43
 None
 0.85A 4k9cB-3hbzA:
undetectable		 4k9cB-3hbzA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9I_A_ADNA401_1
(SUGAR KINASE)		 3hbz PUTATIVE GLYCOSIDE
HYDROLASE
(Bacteroides
thetaiotaomicron) 		5 / 12 ILE A 203
GLY A 204
GLY A 222
LEU A 355
THR A  43
 None
 0.86A 4k9iA-3hbzA:
undetectable		 4k9iA-3hbzA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9I_B_ADNB401_1
(SUGAR KINASE)		 3hbz PUTATIVE GLYCOSIDE
HYDROLASE
(Bacteroides
thetaiotaomicron) 		5 / 12 ILE A 203
GLY A 204
GLY A 222
LEU A 355
THR A  43
 None
 0.87A 4k9iB-3hbzA:
undetectable		 4k9iB-3hbzA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAD_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3hbz PUTATIVE GLYCOSIDE
HYDROLASE
(Bacteroides
thetaiotaomicron) 		5 / 12 ILE A 203
GLY A 204
GLY A 222
LEU A 355
THR A  43
 None
 0.85A 4kadA-3hbzA:
undetectable		 4kadA-3hbzA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAD_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3hbz PUTATIVE GLYCOSIDE
HYDROLASE
(Bacteroides
thetaiotaomicron) 		5 / 12 ILE A 203
GLY A 204
GLY A 222
LEU A 355
THR A  43
 None
 0.87A 4kadB-3hbzA:
undetectable		 4kadB-3hbzA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBX_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3hbz PUTATIVE GLYCOSIDE
HYDROLASE
(Bacteroides
thetaiotaomicron) 		5 / 12 ILE A 203
GLY A 204
GLY A 222
LEU A 355
THR A  43
 None
 0.86A 4lbxA-3hbzA:
undetectable		 4lbxA-3hbzA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBX_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3hbz PUTATIVE GLYCOSIDE
HYDROLASE
(Bacteroides
thetaiotaomicron) 		5 / 12 ILE A 203
GLY A 204
GLY A 222
LEU A 355
THR A  43
 None
 0.87A 4lbxB-3hbzA:
undetectable		 4lbxB-3hbzA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LC4_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3hbz PUTATIVE GLYCOSIDE
HYDROLASE
(Bacteroides
thetaiotaomicron) 		5 / 12 ILE A 203
GLY A 204
GLY A 222
LEU A 355
THR A  43
 None
 0.85A 4lc4A-3hbzA:
undetectable		 4lc4A-3hbzA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LC4_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3hbz PUTATIVE GLYCOSIDE
HYDROLASE
(Bacteroides
thetaiotaomicron) 		5 / 12 ILE A 203
GLY A 204
GLY A 222
LEU A 355
THR A  43
 None
 0.86A 4lc4B-3hbzA:
undetectable		 4lc4B-3hbzA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PD5_A_GEOA501_1
(NUPC FAMILY PROTEIN)		 3hbz PUTATIVE GLYCOSIDE
HYDROLASE
(Bacteroides
thetaiotaomicron) 		5 / 12 GLY A 222
ALA A 328
VAL A 330
TYR A 261
ASN A 278
 None
 1.17A 4pd5A-3hbzA:
undetectable		 4pd5A-3hbzA:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PD9_A_ADNA501_1
(NUPC FAMILY PROTEIN)		 3hbz PUTATIVE GLYCOSIDE
HYDROLASE
(Bacteroides
thetaiotaomicron) 		5 / 12 GLY A 222
ALA A 328
VAL A 330
TYR A 261
ASN A 278
 None
 1.16A 4pd9A-3hbzA:
undetectable		 4pd9A-3hbzA:
22.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TL8_A_X2NA502_2
(PROTEIN CYP51)		 3hbz PUTATIVE GLYCOSIDE
HYDROLASE
(Bacteroides
thetaiotaomicron) 		4 / 6 PRO A  58
PRO A 224
LEU A 223
PHE A 225
 None
None
None
ACT  A   7 (-4.4A)
 0.94A 5tl8A-3hbzA:
undetectable		 5tl8A-3hbzA:
21.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FOS_A_PQNA2001_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A1)		 3hbz PUTATIVE GLYCOSIDE
HYDROLASE
(Bacteroides
thetaiotaomicron) 		4 / 6 MET A  41
GLY A  38
ALA A  66
LEU A  65
 None
 1.03A 6fosA-3hbzA:
undetectable		 6fosA-3hbzA:
12.20