SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3hc4'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_A_CLMA1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 3hc4 IMMUNOGLOBULIN IGG1
FAB, HEAVY CHAIN
(Homo
sapiens) 		4 / 7 GLY H  54
PRO H  53
ILE H  51
GLY H  56
 None
 0.84A 1usqA-3hc4H:
undetectable		 1usqA-3hc4H:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_C_CLMC1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 3hc4 IMMUNOGLOBULIN IGG1
FAB, HEAVY CHAIN
(Homo
sapiens) 		4 / 6 GLY H  54
PRO H  53
ILE H  51
GLY H  56
 None
 0.84A 1usqC-3hc4H:
undetectable		 1usqC-3hc4H:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_D_CLMD1142_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 3hc4 IMMUNOGLOBULIN IGG1
FAB, HEAVY CHAIN
(Homo
sapiens) 		4 / 6 GLY H  54
PRO H  53
ILE H  51
GLY H  56
 None
 0.85A 1usqD-3hc4H:
undetectable		 1usqD-3hc4H:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_E_CLME1143_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 3hc4 IMMUNOGLOBULIN IGG1
FAB, HEAVY CHAIN
(Homo
sapiens) 		4 / 6 GLY H  54
PRO H  53
ILE H  51
GLY H  56
 None
 0.85A 1usqE-3hc4H:
undetectable		 1usqE-3hc4H:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1USQ_F_CLMF1144_0
(DR HEMAGGLUTININ
STRUCTURAL SUBUNIT)		 3hc4 IMMUNOGLOBULIN IGG1
FAB, HEAVY CHAIN
(Homo
sapiens) 		4 / 7 GLY H  54
PRO H  53
ILE H  51
GLY H  56
 None
 0.84A 1usqF-3hc4H:
undetectable		 1usqF-3hc4H:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXQ_A_IMNA2001_1
(SERUM ALBUMIN)		 3hc4 IMMUNOGLOBULIN IGG1
FAB, HEAVY CHAIN
(Homo
sapiens) 		5 / 10 SER H  75
PHE H  29
ALA H  24
LEU H   4
LEU H  34
 None
 1.08A 2bxqA-3hc4H:
undetectable		 2bxqA-3hc4H:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HUO_A_PNNA302_0
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)		 3hc4 IMMUNOGLOBULIN IGG1
FAB, HEAVY CHAIN
(Homo
sapiens) 		4 / 6 LEU H 192
GLY H 193
ALA H 128
PRO H 129
 None
 0.46A 3huoA-3hc4H:
undetectable		 3huoA-3hc4H:
22.22
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4M7K_H_ACTH302_0
(10H10 HEAVY CHAIN)		 3hc4 IMMUNOGLOBULIN IGG1
FAB, HEAVY CHAIN
(Homo
sapiens) 		4 / 5 VAL H   2
TYR H  27
ARG H  98
TYR H 105
 None
 0.20A 4m7kH-3hc4H:
26.1		 4m7kH-3hc4H:
80.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A94_B_ZOTB3001_0
(5-HYDROXYTRYPTAMINE
RECEPTOR 2A,SOLUBLE
CYTOCHROME B562)		 3hc4 IMMUNOGLOBULIN IGG1
FAB, HEAVY CHAIN
(Homo
sapiens) 		6 / 12 VAL H 187
THR H 138
LEU H 162
VAL H 166
GLY H 165
VAL H 214
 None
 1.49A 6a94B-3hc4H:
undetectable		 6a94B-3hc4H:
17.55