SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3hc7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GX8_A_RTLA1163_0
(BETA-LACTOGLOBULIN)		 3hc7 GENE 12 PROTEIN
(Mycobacterium
virus
D29) 		5 / 9 LEU A 207
LEU A 218
GLU A 178
ILE A 222
PHE A 193
 None
 1.49A 1gx8A-3hc7A:
undetectable		 1gx8A-3hc7A:
21.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QX6_B_ML1B233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3hc7 GENE 12 PROTEIN
(Mycobacterium
virus
D29) 		4 / 6 GLY A 184
GLY A 215
PHE A 193
PHE A  47
 None
 1.03A 2qx6A-3hc7A:
4.3
2qx6B-3hc7A:
4.4		 2qx6A-3hc7A:
20.58
2qx6B-3hc7A:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARR_A_PNXA606_1
(CHITINASE A)		 3hc7 GENE 12 PROTEIN
(Mycobacterium
virus
D29) 		4 / 7 GLY A  11
ASP A  25
TYR A  81
ARG A 244
 None
 1.14A 3arrA-3hc7A:
2.2		 3arrA-3hc7A:
17.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA606_1
(CHITINASE A)		 3hc7 GENE 12 PROTEIN
(Mycobacterium
virus
D29) 		4 / 7 GLY A  11
ASP A  25
TYR A  81
ARG A 244
 None
 1.10A 3aruA-3hc7A:
undetectable		 3aruA-3hc7A:
17.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXV_C_478C200_1
(HIV-1 PROTEASE)		 3hc7 GENE 12 PROTEIN
(Mycobacterium
virus
D29) 		5 / 9 GLY A  80
ASP A 160
VAL A 158
GLY A  89
VAL A  91
 None
 0.92A 3oxvC-3hc7A:
undetectable		 3oxvC-3hc7A:
17.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3R_A_9PLA501_1
(CYTOCHROME P450 2A6)		 3hc7 GENE 12 PROTEIN
(Mycobacterium
virus
D29) 		5 / 11 VAL A 200
PHE A 193
ILE A 222
GLY A 184
LEU A 204
 None
 1.10A 3t3rA-3hc7A:
undetectable		 3t3rA-3hc7A:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XV2_A_P06A801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 3hc7 GENE 12 PROTEIN
(Mycobacterium
virus
D29) 		4 / 4 GLY A  21
LEU A 251
PHE A 250
ILE A 114
 None
 0.84A 4xv2A-3hc7A:
undetectable		 4xv2A-3hc7A:
23.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XV2_B_P06B801_2
(SERINE/THREONINE-PRO
TEIN KINASE B-RAF)		 3hc7 GENE 12 PROTEIN
(Mycobacterium
virus
D29) 		4 / 4 GLY A  89
VAL A  57
PHE A 106
ILE A  64
 None
 1.11A 4xv2B-3hc7A:
undetectable		 4xv2B-3hc7A:
23.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y4D_A_CFFA411_1
(ENDOTHIAPEPSIN)		 3hc7 GENE 12 PROTEIN
(Mycobacterium
virus
D29) 		4 / 6 LEU A 110
LEU A 151
PHE A 156
ILE A 114
 None
 1.27A 4y4dA-3hc7A:
undetectable		 4y4dA-3hc7A:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0Y_A_FOLA201_1
(CONSERVED
HYPOTHETICAL
MEMBRANE PROTEIN)		 3hc7 GENE 12 PROTEIN
(Mycobacterium
virus
D29) 		3 / 3 ARG A 159
LYS A 112
GLU A 157
 None
 0.77A 5d0yA-3hc7A:
undetectable		 5d0yA-3hc7A:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_C_SAMC902_0
(MRNA CAPPING ENZYME
P5)		 3hc7 GENE 12 PROTEIN
(Mycobacterium
virus
D29) 		5 / 12 LEU A 241
TYR A  81
GLY A  11
PRO A  15
THR A  12
 None
 1.34A 5x6yC-3hc7A:
undetectable		 5x6yC-3hc7A:
14.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EMU_A_SAMA501_0
(TRNA
(GUANINE(9)-/ADENINE
(9)-N1)-METHYLTRANSF
ERASE)		 3hc7 GENE 12 PROTEIN
(Mycobacterium
virus
D29) 		5 / 12 LEU A 218
ILE A 212
ILE A 222
VAL A 187
ILE A 183
 None
 1.01A 6emuA-3hc7A:
undetectable		 6emuA-3hc7A:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FBV_D_FI8D1904_1
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA')		 3hc7 GENE 12 PROTEIN
(Mycobacterium
virus
D29) 		4 / 8 ASP A 160
ARG A 121
VAL A  57
GLN A 203
 None
 0.93A 6fbvD-3hc7A:
undetectable		 6fbvD-3hc7A:
11.20