SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3hcj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1YA4_A_CTXA11_1 (CES1 PROTEIN)	3hcj	PEPTIDE METHIONINE SULFOXIDE REDUCTASE (Xanthomonas campestris)	4 / 8	LEU A 109 GLY A 110 LEU A 131 PRO A 74	None	0.83A	1ya4A-3hcjA: undetectable	1ya4A-3hcjA: 15.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1YA4_B_CTXB1283_1 (CES1 PROTEIN)	3hcj	PEPTIDE METHIONINE SULFOXIDE REDUCTASE (Xanthomonas campestris)	4 / 7	LEU A 109 GLY A 110 LEU A 131 PRO A 74	None	0.82A	1ya4B-3hcjA: undetectable	1ya4B-3hcjA: 15.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1YA4_B_CTXB2_2 (CES1 PROTEIN)	3hcj	PEPTIDE METHIONINE SULFOXIDE REDUCTASE (Xanthomonas campestris)	4 / 4	LEU A 131 PRO A 37 ILE A 100 LEU A 109	None	1.02A	1ya4B-3hcjA: undetectable	1ya4B-3hcjA: 15.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1YA4_C_CTXC3_2 (CES1 PROTEIN)	3hcj	PEPTIDE METHIONINE SULFOXIDE REDUCTASE (Xanthomonas campestris)	4 / 4	LEU A 131 PRO A 37 ILE A 100 LEU A 109	None	1.09A	1ya4C-3hcjA: undetectable	1ya4C-3hcjA: 15.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MAF_A_XINA403_2 (MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE)	3hcj	PEPTIDE METHIONINE SULFOXIDE REDUCTASE (Xanthomonas campestris)	4 / 5	CYH A 56 CYH A 102 LEU A 58 ASP A 5	ZN A1000 (-2.3A) ZN A1000 (-2.2A) None None	1.49A	5mafA-3hcjA: undetectable	5mafA-3hcjA: 21.43

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1YA4_A_CTXA11_1","CES1 PROTEIN","3hcj","PEPTIDE METHIONINE SULFOXIDE REDUCTASE","Xanthomonas campestris",4,"LEU A 109;GLY A 110;LEU A 131;PRO A  74","None","0.83A","1ya4A-3hcjA:undetectable","1ya4A-3hcjA:15.50"],["1YA4_B_CTXB1283_1","CES1 PROTEIN","3hcj","PEPTIDE METHIONINE SULFOXIDE REDUCTASE","Xanthomonas campestris",4,"LEU A 109;GLY A 110;LEU A 131;PRO A  74","None","0.82A","1ya4B-3hcjA:undetectable","1ya4B-3hcjA:15.50"],["1YA4_B_CTXB2_2","CES1 PROTEIN","3hcj","PEPTIDE METHIONINE SULFOXIDE REDUCTASE","Xanthomonas campestris",4,"LEU A 131;PRO A  37;ILE A 100;LEU A 109","None","1.02A","1ya4B-3hcjA:undetectable","1ya4B-3hcjA:15.50"],["1YA4_C_CTXC3_2","CES1 PROTEIN","3hcj","PEPTIDE METHIONINE SULFOXIDE REDUCTASE","Xanthomonas campestris",4,"LEU A 131;PRO A  37;ILE A 100;LEU A 109","None","1.09A","1ya4C-3hcjA:undetectable","1ya4C-3hcjA:15.50"],["5MAF_A_XINA403_2","MATERNAL EMBRYONIC LEUCINE ZIPPER KINASE","3hcj","PEPTIDE METHIONINE SULFOXIDE REDUCTASE","Xanthomonas campestris",4,"CYH A  56;CYH A 102;LEU A  58;ASP A   5"," ZN A1000 (-2.3A); ZN A1000 (-2.2A);None;None","1.49A","5mafA-3hcjA:undetectable","5mafA-3hcjA:21.43"]]