SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3hd5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XZ5_A_ACHA1210_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 3hd5 THIOL:DISULFIDE
INTERCHANGE PROTEIN
DSBA
(Bordetella
parapertussis) 		4 / 6 TYR A  99
TYR A  56
CYH A  61
ILE A  86
 None
 1.23A 2xz5A-3hd5A:
undetectable
2xz5B-3hd5A:
undetectable		 2xz5A-3hd5A:
20.89
2xz5B-3hd5A:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCJ_A_AZMA229_2
(CARBONIC ANHYDRASE)		 3hd5 THIOL:DISULFIDE
INTERCHANGE PROTEIN
DSBA
(Bordetella
parapertussis) 		3 / 3 GLN A  83
PHE A  54
TYR A  99
 None
 0.83A 3ucjB-3hd5A:
undetectable		 3ucjB-3hd5A:
24.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCJ_B_AZMB229_1
(CARBONIC ANHYDRASE)		 3hd5 THIOL:DISULFIDE
INTERCHANGE PROTEIN
DSBA
(Bordetella
parapertussis) 		3 / 3 GLN A  83
PHE A  54
TYR A  99
 None
 0.84A 3ucjA-3hd5A:
undetectable		 3ucjA-3hd5A:
24.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BQT_C_C5EC301_0
(SOLUBLE
ACETYLCHOLINE
RECEPTOR)		 3hd5 THIOL:DISULFIDE
INTERCHANGE PROTEIN
DSBA
(Bordetella
parapertussis) 		4 / 8 VAL A  84
TYR A  56
CYH A  61
ILE A  86
 None
 1.17A 4bqtC-3hd5A:
undetectable
4bqtD-3hd5A:
undetectable		 4bqtC-3hd5A:
20.89
4bqtD-3hd5A:
20.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YJI_A_TYLA502_1
(ARYL ACYLAMIDASE)		 3hd5 THIOL:DISULFIDE
INTERCHANGE PROTEIN
DSBA
(Bordetella
parapertussis) 		4 / 7 LEU A 164
GLY A 180
GLY A 179
ALA A 177
 None
 0.53A 4yjiA-3hd5A:
undetectable		 4yjiA-3hd5A:
17.47