SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3hd8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A7Y_A_DVAA8_0
(ACTINOMYCIN D)		 3hd8 XYLANASE INHIBITOR
(Triticum
aestivum) 		3 / 3 THR A 109
THR A 108
PRO A   4
 None
 0.82A 1a7yA-3hd8A:
undetectable		 1a7yA-3hd8A:
3.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A7Y_B_DVAB8_0
(ACTINOMYCIN D)		 3hd8 XYLANASE INHIBITOR
(Triticum
aestivum) 		3 / 3 THR A 109
THR A 108
PRO A   4
 None
 0.85A 1a7yB-3hd8A:
undetectable		 1a7yB-3hd8A:
3.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERR_A_RALA600_2
(ESTROGEN RECEPTOR)		 3hd8 XYLANASE INHIBITOR
(Triticum
aestivum) 		4 / 6 LEU A 374
LEU A 360
LEU A 306
LEU A 304
 None
 0.92A 1errA-3hd8A:
undetectable		 1errA-3hd8A:
20.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_F_DVAF8_0
(ACTINOMYCIN D)		 3hd8 XYLANASE INHIBITOR
(Triticum
aestivum) 		3 / 3 THR A 109
THR A 108
PRO A   4
 None
 0.86A 1i3wF-3hd8A:
undetectable		 1i3wF-3hd8A:
3.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_G_DVAG2_0
(ACTINOMYCIN D)		 3hd8 XYLANASE INHIBITOR
(Triticum
aestivum) 		3 / 3 THR A 108
PRO A   4
THR A 109
 None
 0.85A 1i3wG-3hd8A:
undetectable		 1i3wG-3hd8A:
3.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PXX_B_DIFB1701_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3hd8 XYLANASE INHIBITOR
(Triticum
aestivum) 		5 / 9 LEU A  17
LEU A 132
VAL A 142
GLY A 141
SER A  27
 None
 1.29A 1pxxB-3hd8A:
undetectable		 1pxxB-3hd8A:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QFI_A_DVAA8_0
(ACTINOMYCIN X2)		 3hd8 XYLANASE INHIBITOR
(Triticum
aestivum) 		3 / 3 THR A 109
THR A 108
PRO A   4
 None
 0.82A 1qfiA-3hd8A:
undetectable		 1qfiA-3hd8A:
3.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_F_DVAF2_0
(7-AMINO-ACTINOMYCIN
D)		 3hd8 XYLANASE INHIBITOR
(Triticum
aestivum) 		3 / 3 THR A 108
PRO A   4
THR A 109
 None
 0.84A 1unjF-3hd8A:
undetectable		 1unjF-3hd8A:
3.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_F_DVAF8_0
(7-AMINO-ACTINOMYCIN
D)		 3hd8 XYLANASE INHIBITOR
(Triticum
aestivum) 		3 / 3 THR A 109
THR A 108
PRO A   4
 None
 0.83A 1unjF-3hd8A:
undetectable		 1unjF-3hd8A:
3.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z95_A_198A501_2
(ANDROGEN RECEPTOR)		 3hd8 XYLANASE INHIBITOR
(Triticum
aestivum) 		4 / 6 LEU A 245
LEU A 240
MET A 314
LEU A 350
 None
 0.79A 1z95A-3hd8A:
undetectable		 1z95A-3hd8A:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_B_SC2B1294_1
(FICOLIN-2)		 3hd8 XYLANASE INHIBITOR
(Triticum
aestivum) 		5 / 9 GLY A 138
SER A 139
LEU A 135
LEU A  17
ASP A  12
 None
 1.36A 2j2pB-3hd8A:
undetectable
2j2pC-3hd8A:
undetectable		 2j2pB-3hd8A:
18.43
2j2pC-3hd8A:
18.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_A_ASDA1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 3hd8 XYLANASE INHIBITOR
(Triticum
aestivum) 		4 / 7 PHE A 104
ALA A 178
LEU A   6
ALA A 106
 None
 0.96A 2vcvA-3hd8A:
undetectable		 2vcvA-3hd8A:
18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_G_ASDG1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 3hd8 XYLANASE INHIBITOR
(Triticum
aestivum) 		4 / 7 PHE A 104
ALA A 178
LEU A   6
ALA A 106
 None
 1.00A 2vcvG-3hd8A:
undetectable		 2vcvG-3hd8A:
18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_L_ASDL1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 3hd8 XYLANASE INHIBITOR
(Triticum
aestivum) 		4 / 7 PHE A 104
ALA A 178
LEU A   6
ALA A 106
 None
 0.94A 2vcvL-3hd8A:
undetectable		 2vcvL-3hd8A:
18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VQ5_B_LDPB1197_1
(S-NORCOCLAURINE
SYNTHASE)		 3hd8 XYLANASE INHIBITOR
(Triticum
aestivum) 		4 / 7 LEU A 168
LEU A 360
PHE A 362
LEU A 145
 None
 0.96A 2vq5B-3hd8A:
undetectable		 2vq5B-3hd8A:
18.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VQR_A_ACTA1002_0
(PUTATIVE
OXIDOREDUCTASE)		 3hd8 XYLANASE INHIBITOR
(Triticum
aestivum) 		4 / 6 GLY A 141
VAL A 142
TRP A  38
THR A  19
 None
 1.24A 3vqrA-3hd8A:
undetectable		 3vqrA-3hd8A:
24.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LTW_A_STRA301_1
(ANCESTRAL STEROID
RECEPTOR 2)		 3hd8 XYLANASE INHIBITOR
(Triticum
aestivum) 		5 / 12 LEU A  36
LEU A 150
ALA A 151
GLN A 155
LEU A  28
 None
 1.03A 4ltwA-3hd8A:
undetectable		 4ltwA-3hd8A:
18.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X1K_B_LOCB502_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 3hd8 XYLANASE INHIBITOR
(Triticum
aestivum) 		5 / 12 VAL A  29
LEU A  99
ALA A 124
LEU A  36
ALA A 127
 None
 1.22A 4x1kA-3hd8A:
undetectable
4x1kB-3hd8A:
undetectable		 4x1kA-3hd8A:
21.89
4x1kB-3hd8A:
21.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AOX_C_ACTC1001_0
(ALU JO CONSENSUS RNA
SIGNAL RECOGNITION
PARTICLE 14 KDA
PROTEIN)		 3hd8 XYLANASE INHIBITOR
(Triticum
aestivum) 		3 / 3 TYR A 285
THR A 327
THR A 289
 None
 0.76A 5aoxB-3hd8A:
undetectable		 5aoxB-3hd8A:
12.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AOX_F_ACTF1001_0
(ALU JO CONSENSUS RNA
SIGNAL RECOGNITION
PARTICLE 14 KDA
PROTEIN)		 3hd8 XYLANASE INHIBITOR
(Triticum
aestivum) 		3 / 3 TYR A 285
THR A 327
THR A 289
 None
 0.75A 5aoxE-3hd8A:
undetectable		 5aoxE-3hd8A:
12.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E72_A_SAMA400_0
(N2,
N2-DIMETHYLGUANOSINE
TRNA
METHYLTRANSFERASE)		 3hd8 XYLANASE INHIBITOR
(Triticum
aestivum) 		5 / 12 PHE A 180
GLY A   2
ALA A 178
PRO A 153
LEU A 145
 None
 0.95A 5e72A-3hd8A:
undetectable		 5e72A-3hd8A:
23.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NUJ_A_Z80A201_1
(BETA-LACTOGLOBULIN)		 3hd8 XYLANASE INHIBITOR
(Triticum
aestivum) 		4 / 8 VAL A 348
PHE A 332
LEU A 245
VAL A 302
 None
 0.83A 5nujA-3hd8A:
undetectable		 5nujA-3hd8A:
12.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGU_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3hd8 XYLANASE INHIBITOR
(Triticum
aestivum) 		3 / 3 VAL A 234
VAL A 348
GLN A 354
 None
 0.72A 5qguA-3hd8A:
undetectable		 5qguA-3hd8A:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGV_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3hd8 XYLANASE INHIBITOR
(Triticum
aestivum) 		3 / 3 VAL A 234
VAL A 348
GLN A 354
 None
 0.68A 5qgvA-3hd8A:
undetectable		 5qgvA-3hd8A:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGW_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3hd8 XYLANASE INHIBITOR
(Triticum
aestivum) 		3 / 3 VAL A 234
VAL A 348
GLN A 354
 None
 0.68A 5qgwA-3hd8A:
undetectable		 5qgwA-3hd8A:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QGX_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3hd8 XYLANASE INHIBITOR
(Triticum
aestivum) 		3 / 3 VAL A 234
VAL A 348
GLN A 354
 None
 0.69A 5qgxA-3hd8A:
undetectable		 5qgxA-3hd8A:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH1_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3hd8 XYLANASE INHIBITOR
(Triticum
aestivum) 		3 / 3 VAL A 234
VAL A 348
GLN A 354
 None
 0.68A 5qh1A-3hd8A:
undetectable		 5qh1A-3hd8A:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH4_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3hd8 XYLANASE INHIBITOR
(Triticum
aestivum) 		3 / 3 VAL A 234
VAL A 348
GLN A 354
 None
 0.69A 5qh4A-3hd8A:
undetectable		 5qh4A-3hd8A:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH5_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3hd8 XYLANASE INHIBITOR
(Triticum
aestivum) 		3 / 3 VAL A 234
VAL A 348
GLN A 354
 None
 0.66A 5qh5A-3hd8A:
undetectable		 5qh5A-3hd8A:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH6_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3hd8 XYLANASE INHIBITOR
(Triticum
aestivum) 		3 / 3 VAL A 234
VAL A 348
GLN A 354
 None
 0.67A 5qh6A-3hd8A:
undetectable		 5qh6A-3hd8A:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QH9_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3hd8 XYLANASE INHIBITOR
(Triticum
aestivum) 		3 / 3 VAL A 234
VAL A 348
GLN A 354
 None
 0.68A 5qh9A-3hd8A:
undetectable		 5qh9A-3hd8A:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHC_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3hd8 XYLANASE INHIBITOR
(Triticum
aestivum) 		3 / 3 VAL A 234
VAL A 348
GLN A 354
 None
 0.70A 5qhcA-3hd8A:
undetectable		 5qhcA-3hd8A:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHE_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3hd8 XYLANASE INHIBITOR
(Triticum
aestivum) 		3 / 3 VAL A 234
VAL A 348
GLN A 354
 None
 0.71A 5qheA-3hd8A:
undetectable		 5qheA-3hd8A:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHF_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3hd8 XYLANASE INHIBITOR
(Triticum
aestivum) 		3 / 3 VAL A 234
VAL A 348
GLN A 354
 None
 0.68A 5qhfA-3hd8A:
undetectable		 5qhfA-3hd8A:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5QHG_A_ACTA301_0
(PEROXISOMAL COENZYME
A DIPHOSPHATASE
NUDT7)		 3hd8 XYLANASE INHIBITOR
(Triticum
aestivum) 		3 / 3 VAL A 234
VAL A 348
GLN A 354
 None
 0.69A 5qhgA-3hd8A:
undetectable		 5qhgA-3hd8A:
20.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TUI_B_CTCB405_1
(TETRACYCLINE
DESTRUCTASE TET(50))		 3hd8 XYLANASE INHIBITOR
(Triticum
aestivum) 		4 / 5 ASP A  31
ARG A 239
LEU A 199
MET A 364
 None
 1.12A 5tuiB-3hd8A:
undetectable		 5tuiB-3hd8A:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUO_B_MTLB805_0
(NITRIC OXIDE
SYNTHASE, BRAIN)		 3hd8 XYLANASE INHIBITOR
(Triticum
aestivum) 		4 / 8 ASN A 119
GLN A 160
PHE A 104
ASN A 107
 None
 1.34A 5vuoB-3hd8A:
undetectable		 5vuoB-3hd8A:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DK1_B_GM4B301_0
(SIGMA NON-OPIOID
INTRACELLULAR
RECEPTOR 1)		 3hd8 XYLANASE INHIBITOR
(Triticum
aestivum) 		5 / 11 VAL A 234
LEU A 245
ASP A 248
ALA A 212
LEU A 306
 None
 1.39A 6dk1B-3hd8A:
undetectable		 6dk1B-3hd8A:
20.10