SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3hde'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1T7I_A_017A200_1 (POL POLYPROTEIN)	3hde	LYSOZYME (Escherichia virus Lambda)	5 / 10	GLY A 15 ALA A 12 ILE A 159 GLY A 100 THR A 26	None	0.98A	1t7iA-3hdeA: undetectable	1t7iA-3hdeA: 18.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BWC_A_SAMA501_0 (SPERMIDINE SYNTHASE)	3hde	LYSOZYME (Escherichia virus Lambda)	5 / 12	ILE A 20 GLY A 100 ILE A 18 VAL A 82 GLY A 16	None	0.99A	3bwcA-3hdeA: undetectable	3bwcA-3hdeA: 21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3EL9_A_DR7A100_2 (PROTEASE)	3hde	LYSOZYME (Escherichia virus Lambda)	5 / 10	GLY A 15 ALA A 12 ILE A 159 GLY A 100 THR A 26	None	1.04A	3el9B-3hdeA: undetectable	3el9B-3hdeA: 18.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4LHM_A_AZZA510_1 (THYMIDINE PHOSPHORYLASE)	3hde	LYSOZYME (Escherichia virus Lambda)	5 / 11	LEU A 5 ARG A 152 ILE A 25 SER A 104 LEU A 75	None	1.31A	4lhmA-3hdeA: undetectable	4lhmA-3hdeA: 18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QWP_B_GCSB307_1 (CHITOSANASE)	3hde	LYSOZYME (Escherichia virus Lambda)	4 / 7	GLU A 35 THR A 50 GLY A 54 THR A 56	None	0.88A	4qwpB-3hdeA: 2.0	4qwpB-3hdeA: 22.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5EVY_X_SALX502_1 (SALICYLATE HYDROXYLASE)	3hde	LYSOZYME (Escherichia virus Lambda)	4 / 5	SER A 117 MET A 98 LEU A 102 PHE A 105	None	1.47A	5evyX-3hdeA: undetectable	5evyX-3hdeA: 17.73

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1T7I_A_017A200_1","POL POLYPROTEIN","3hde","LYSOZYME","Escherichia virus Lambda",5,"GLY A  15;ALA A  12;ILE A 159;GLY A 100;THR A  26","None","0.98A","1t7iA-3hdeA:undetectable","1t7iA-3hdeA:18.34"],["3BWC_A_SAMA501_0","SPERMIDINE SYNTHASE","3hde","LYSOZYME","Escherichia virus Lambda",5,"ILE A  20;GLY A 100;ILE A  18;VAL A  82;GLY A  16","None","0.99A","3bwcA-3hdeA:undetectable","3bwcA-3hdeA:21.59"],["3EL9_A_DR7A100_2","PROTEASE;PROTEASE","3hde","LYSOZYME","Escherichia virus Lambda",5,"GLY A  15;ALA A  12;ILE A 159;GLY A 100;THR A  26","None","1.04A","3el9B-3hdeA:undetectable","3el9B-3hdeA:18.34"],["4LHM_A_AZZA510_1","THYMIDINE PHOSPHORYLASE","3hde","LYSOZYME","Escherichia virus Lambda",5,"LEU A   5;ARG A 152;ILE A  25;SER A 104;LEU A  75","None","1.31A","4lhmA-3hdeA:undetectable","4lhmA-3hdeA:18.90"],["4QWP_B_GCSB307_1","CHITOSANASE","3hde","LYSOZYME","Escherichia virus Lambda",4,"GLU A  35;THR A  50;GLY A  54;THR A  56","None","0.88A","4qwpB-3hdeA:2.0","4qwpB-3hdeA:22.22"],["5EVY_X_SALX502_1","SALICYLATE HYDROXYLASE","3hde","LYSOZYME","Escherichia virus Lambda",4,"SER A 117;MET A  98;LEU A 102;PHE A 105","None","1.47A","5evyX-3hdeA:undetectable","5evyX-3hdeA:17.73"]]