SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3hdf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C6Z_B_ROCB505_1
(PROTEIN (PROTEASE))		 3hdf LYSOZYME
(Escherichia
virus
Lambda) 		5 / 12 ALA A 131
ASP A 127
GLY A 163
PRO A  95
ILE A 123
 None
 0.90A 1c6zA-3hdfA:
undetectable		 1c6zA-3hdfA:
21.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FB7_A_ROCA100_1
(HIV-1 PROTEASE)		 3hdf LYSOZYME
(Escherichia
virus
Lambda) 		5 / 12 ALA A 131
ASP A 127
GLY A 163
PRO A  95
ILE A 123
 None
 1.00A 1fb7A-3hdfA:
undetectable		 1fb7A-3hdfA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HPV_B_478B200_2
(HIV-1 PROTEASE)		 3hdf LYSOZYME
(Escherichia
virus
Lambda) 		5 / 9 ALA A 131
ASP A 127
GLY A 163
PRO A  95
ILE A 123
 None
 1.04A 1hpvB-3hdfA:
undetectable		 1hpvB-3hdfA:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HSH_A_MK1A401_1
(HIV-II PROTEASE)		 3hdf LYSOZYME
(Escherichia
virus
Lambda) 		6 / 12 ALA A 131
ASP A 127
GLY A 163
PRO A  95
ILE A  94
ILE A 123
 None
 1.32A 1hshA-3hdfA:
undetectable		 1hshA-3hdfA:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HXB_A_ROCA100_3
(HIV-1 PROTEASE)		 3hdf LYSOZYME
(Escherichia
virus
Lambda) 		5 / 12 ALA A 131
ASP A 127
GLY A 163
PRO A  95
ILE A 123
 None
 0.95A 1hxbB-3hdfA:
undetectable		 1hxbB-3hdfA:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OHR_A_1UNA201_1
(ASPARTYLPROTEASE)		 3hdf LYSOZYME
(Escherichia
virus
Lambda) 		5 / 11 ALA A 131
ASP A 127
GLY A 163
PRO A  95
ILE A 123
 None
 0.87A 1ohrA-3hdfA:
undetectable		 1ohrA-3hdfA:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SDU_B_MK1B902_2
(PROTEASE RETROPEPSIN)		 3hdf LYSOZYME
(Escherichia
virus
Lambda) 		5 / 12 ALA A 131
ASP A 127
GLY A 163
PRO A  95
ILE A 123
 None
 0.98A 1sduB-3hdfA:
undetectable		 1sduB-3hdfA:
20.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVS_B_MK1B902_3
(POL POLYPROTEIN)		 3hdf LYSOZYME
(Escherichia
virus
Lambda) 		5 / 12 ALA A 131
ASP A 127
GLY A 163
PRO A  95
ILE A 123
 None
 0.99A 2avsB-3hdfA:
undetectable		 2avsB-3hdfA:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z54_A_AB1A200_1
(HIV-1 PROTEASE)		 3hdf LYSOZYME
(Escherichia
virus
Lambda) 		5 / 12 ALA A 131
ASP A 127
GLY A 163
PRO A  95
ILE A 123
 None
 0.99A 2z54A-3hdfA:
undetectable		 2z54A-3hdfA:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKX_B_1UNB201_2
(PROTEASE)		 3hdf LYSOZYME
(Escherichia
virus
Lambda) 		5 / 11 ALA A 131
ASP A 127
GLY A 163
PRO A  95
ILE A 123
 None
 0.87A 3ekxB-3hdfA:
undetectable		 3ekxB-3hdfA:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_D_ROCD201_1
(HIV-1 PROTEASE)		 3hdf LYSOZYME
(Escherichia
virus
Lambda) 		5 / 12 ALA A 131
ASP A 127
GLY A 163
PRO A  95
ILE A 123
 None
 0.98A 3k4vC-3hdfA:
undetectable		 3k4vC-3hdfA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDU_A_ROCA101_1
(PROTEASE)		 3hdf LYSOZYME
(Escherichia
virus
Lambda) 		5 / 12 ALA A 131
ASP A 127
GLY A 163
PRO A  95
ILE A 123
 None
 0.93A 3nduA-3hdfA:
undetectable		 3nduA-3hdfA:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S54_B_017B201_2
(PROTEASE)		 3hdf LYSOZYME
(Escherichia
virus
Lambda) 		6 / 12 ALA A 131
ASP A 127
GLY A 163
PRO A  95
ILE A  94
ILE A 123
 None
 1.28A 3s54B-3hdfA:
undetectable		 3s54B-3hdfA:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKG_B_ROCB801_2
(PROTEASE)		 3hdf LYSOZYME
(Escherichia
virus
Lambda) 		5 / 12 ALA A 131
ASP A 127
GLY A 163
PRO A  95
ILE A 123
 None
 0.99A 3tkgB-3hdfA:
undetectable		 3tkgB-3hdfA:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKG_C_ROCC901_1
(PROTEASE)		 3hdf LYSOZYME
(Escherichia
virus
Lambda) 		5 / 12 ALA A 131
ASP A 127
GLY A 163
PRO A  95
ILE A 123
 None
 1.01A 3tkgC-3hdfA:
undetectable		 3tkgC-3hdfA:
18.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LL3_A_017A202_2
(PROTEASE)		 3hdf LYSOZYME
(Escherichia
virus
Lambda) 		5 / 9 ALA A 131
ASP A 127
GLY A 163
PRO A  95
ILE A 123
 None
 1.15A 4ll3B-3hdfA:
undetectable		 4ll3B-3hdfA:
18.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR2_A_ROCA101_2
(PROTEASE PR5-SQV)		 3hdf LYSOZYME
(Escherichia
virus
Lambda) 		5 / 11 ALA A 131
ASP A 127
GLY A 163
PRO A  95
ILE A 123
 None
 1.15A 5kr2B-3hdfA:
undetectable		 5kr2B-3hdfA:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DIF_B_TPVB201_0
(HIV-1 PROTEASE)		 3hdf LYSOZYME
(Escherichia
virus
Lambda) 		5 / 12 ALA A 131
ASP A 127
GLY A 163
PRO A  95
ILE A 123
 None
 1.06A 6difA-3hdfA:
undetectable		 6difA-3hdfA:
18.12