SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3hdg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JHA_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 3hdg UNCHARACTERIZED
PROTEIN
(Wolinella
succinogenes) 		4 / 8 THR A  58
GLY A  67
GLY A  39
GLY A  44
 None
 0.77A 1jhaA-3hdgA:
3.0		 1jhaA-3hdgA:
14.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6R_B_CRNB603_1
(CREATINE KINASE
B-TYPE)		 3hdg UNCHARACTERIZED
PROTEIN
(Wolinella
succinogenes) 		4 / 6 THR A  58
VAL A  85
LEU A  68
SER A  87
 None
 1.08A 3b6rB-3hdgA:
undetectable		 3b6rB-3hdgA:
15.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ZOS_B_0LIB1000_2
(EPITHELIAL DISCOIDIN
DOMAIN-CONTAINING
RECEPTOR 1)		 3hdg UNCHARACTERIZED
PROTEIN
(Wolinella
succinogenes) 		5 / 9 LEU A 101
ILE A 111
LEU A  24
ILE A  13
ILE A  11
 None
 1.23A 3zosB-3hdgA:
undetectable		 3zosB-3hdgA:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C9N_A_CAMA1419_0
(CYTOCHROME P450)		 3hdg UNCHARACTERIZED
PROTEIN
(Wolinella
succinogenes) 		4 / 8 LEU A  68
GLY A  67
THR A  58
VAL A  83
 None
 0.74A 4c9nA-3hdgA:
undetectable		 4c9nA-3hdgA:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H3A_A_D16A401_1
(ORF70)		 3hdg UNCHARACTERIZED
PROTEIN
(Wolinella
succinogenes) 		4 / 7 PHE A  48
ILE A  56
ASP A  40
GLY A  41
 None
 0.90A 5h3aA-3hdgA:
undetectable		 5h3aA-3hdgA:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X5Q_E_D16E402_1
(THYMIDYLATE SYNTHASE)		 3hdg UNCHARACTERIZED
PROTEIN
(Wolinella
succinogenes) 		4 / 6 PHE A  48
ILE A  56
ASP A  40
GLY A  41
 None
 0.96A 5x5qE-3hdgA:
undetectable		 5x5qE-3hdgA:
19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GQI_A_ACTA604_0
(CYCLOHEXANONE
MONOOXYGENASE FROM
THERMOCRISPUM
MUNICIPALE)		 3hdg UNCHARACTERIZED
PROTEIN
(Wolinella
succinogenes) 		4 / 6 PRO A  53
ILE A  74
GLY A  49
GLU A  45
 None
 0.91A 6gqiA-3hdgA:
2.8		 6gqiA-3hdgA:
14.31