SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3hdl'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1AEG_A_4APA296_1
(CYTOCHROME C
PEROXIDASE)		 3hdl ROYAL PALM TREE
PEROXIDASE
(Roystonea
regia) 		4 / 8 HIS A 169
GLY A 172
LEU A 245
ASP A 248
 HEM  A 305 (-3.4A)
HEM  A 305 ( 3.2A)
HEM  A 305 (-4.8A)
None
 0.39A 1aegA-3hdlA:
24.4		 1aegA-3hdlA:
19.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERR_B_RALB600_2
(ESTROGEN RECEPTOR)		 3hdl ROYAL PALM TREE
PEROXIDASE
(Roystonea
regia) 		4 / 6 LEU A  55
ASP A  66
MET A  39
LEU A 101
 None
 1.14A 1errB-3hdlA:
undetectable		 1errB-3hdlA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KYV_B_RBFB502_1
(6,7-DIMETHYL-8-RIBIT
YLLUMAZINE SYNTHASE)		 3hdl ROYAL PALM TREE
PEROXIDASE
(Roystonea
regia) 		5 / 11 ILE A 171
LEU A 222
GLY A 167
SER A 166
LEU A 251
 EDO  A 335 (-3.8A)
None
None
HEM  A 305 (-3.6A)
None
 1.29A 1kyvA-3hdlA:
undetectable
1kyvB-3hdlA:
undetectable		 1kyvA-3hdlA:
20.45
1kyvB-3hdlA:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6H_A_MXDA551_1
(PROSTACYCLIN
SYNTHASE)		 3hdl ROYAL PALM TREE
PEROXIDASE
(Roystonea
regia) 		4 / 6 TYR A 200
ALA A 201
LEU A 204
THR A 246
 None
 0.92A 3b6hA-3hdlA:
undetectable		 3b6hA-3hdlA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3F33_A_PFLA2001_1
(FERRITIN LIGHT CHAIN)		 3hdl ROYAL PALM TREE
PEROXIDASE
(Roystonea
regia) 		4 / 6 SER A 199
TYR A 200
LEU A 203
LEU A 242
 None
 1.03A 3f33A-3hdlA:
undetectable		 3f33A-3hdlA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KU1_G_SAMG226_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 3hdl ROYAL PALM TREE
PEROXIDASE
(Roystonea
regia) 		5 / 12 LEU A 101
GLY A  35
GLY A 172
ALA A 105
ILE A 171
 None
HEM  A 305 ( 3.7A)
HEM  A 305 ( 3.2A)
None
EDO  A 335 (-3.8A)
 0.99A 3ku1G-3hdlA:
undetectable		 3ku1G-3hdlA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BLV_A_SAMA1281_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE J)		 3hdl ROYAL PALM TREE
PEROXIDASE
(Roystonea
regia) 		5 / 12 LEU A 245
GLY A 172
GLY A  31
LEU A 244
HIS A 169
 HEM  A 305 (-4.8A)
HEM  A 305 ( 3.2A)
EDO  A 335 ( 3.9A)
None
HEM  A 305 (-3.4A)
 1.15A 4blvA-3hdlA:
undetectable		 4blvA-3hdlA:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FCT_B_C2FB402_1
(THYMIDYLATE SYNTHASE)		 3hdl ROYAL PALM TREE
PEROXIDASE
(Roystonea
regia) 		3 / 3 ASN A 181
ASP A 248
GLY A 243
 None
 0.62A 5fctB-3hdlA:
undetectable		 5fctB-3hdlA:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B89_A_NOVA403_2
(LIPOPOLYSACCHARIDE
EXPORT SYSTEM
ATP-BINDING PROTEIN
LPTB)		 3hdl ROYAL PALM TREE
PEROXIDASE
(Roystonea
regia) 		4 / 6 PHE A 179
LEU A 245
ALA A 174
GLN A 249
 None
HEM  A 305 (-4.8A)
HEM  A 305 (-3.5A)
None
 1.04A 6b89B-3hdlA:
undetectable		 6b89B-3hdlA:
15.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MKE_D_FK5D201_0
(PEPTIDYLPROLYL
ISOMERASE)		 3hdl ROYAL PALM TREE
PEROXIDASE
(Roystonea
regia) 		4 / 4 ASP A 107
ILE A  37
PRO A  34
LEU A  36
 None
HEM  A 305 ( 4.4A)
HEM  A 305 (-4.4A)
None
 1.45A 6mkeA-3hdlA:
undetectable		 6mkeA-3hdlA:
13.38