SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3hdp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CZV_A_AZMA263_1
(CARBONIC ANHYDRASE
13)		 3hdp GLYOXALASE-I
(Clostridium
acetobutylicum) 		5 / 12 HIS A   5
HIS A  75
VAL A 112
VAL A  54
VAL A  32
 NI  A 129 (-3.5A)
NI  A 129 (-3.5A)
None
None
None
 1.21A 3czvA-3hdpA:
undetectable
3czvB-3hdpA:
undetectable		 3czvA-3hdpA:
20.00
3czvB-3hdpA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QF1_A_PZEA6951_1
(LACTOPEROXIDASE)		 3hdp GLYOXALASE-I
(Clostridium
acetobutylicum) 		3 / 3 HIS A   4
ARG A  50
GLU A  52
 None
None
NI  A 129 (-2.6A)
 0.81A 3qf1A-3hdpA:
undetectable		 3qf1A-3hdpA:
15.68