SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3hdt'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KIC_B_SAMB401_0
(METHYLTRANSFERASE
MPPJ)		 3hdt PUTATIVE KINASE
([Clostridium]
symbiosum) 		5 / 12 ILE A 195
GLY A  28
GLY A  24
ILE A  14
ALA A  32
 None
None
PO4  A 301 (-3.6A)
None
None
 1.05A 4kicB-3hdtA:
undetectable		 4kicB-3hdtA:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LAJ_B_ACAB512_1
(HIV-1 YU2 GP120
ENVELOPE
GLYCOPROTEIN)		 3hdt PUTATIVE KINASE
([Clostridium]
symbiosum) 		4 / 6 ARG A  25
GLY A  24
ASP A  41
ARG A 173
 None
PO4  A 301 (-3.6A)
None
PO4  A 301 (-2.8A)
 1.22A 4lajA-3hdtA:
undetectable
4lajB-3hdtA:
undetectable		 4lajA-3hdtA:
19.69
4lajB-3hdtA:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKV_D_AERD601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 3hdt PUTATIVE KINASE
([Clostridium]
symbiosum) 		4 / 5 TYR A 191
GLY A 119
GLU A  19
VAL A 151
 None
CL  A 302 ( 3.7A)
None
None
 1.14A 4nkvD-3hdtA:
undetectable		 4nkvD-3hdtA:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V04_A_0LIA1772_2
(FIBROBLAST GROWTH
FACTOR RECEPTOR 1
(FMS-RELATED
TYROSINE KINASE 2,
PFEIFFER SYNDROME),
ISOFORM CRA_B)		 3hdt PUTATIVE KINASE
([Clostridium]
symbiosum) 		4 / 8 ILE A  13
ARG A  25
LEU A 135
ILE A  14
 None
 0.88A 4v04A-3hdtA:
undetectable		 4v04A-3hdtA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X80_B_SALB203_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR RV2887)		 3hdt PUTATIVE KINASE
([Clostridium]
symbiosum) 		4 / 6 GLY A  21
LEU A 202
ARG A  18
VAL A 140
 PO4  A 301 (-3.5A)
None
PO4  A 301 ( 3.9A)
None
 0.96A 5x80A-3hdtA:
undetectable
5x80B-3hdtA:
undetectable		 5x80A-3hdtA:
21.46
5x80B-3hdtA:
21.46