SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3hdu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UW6_A_NCTA1208_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 3hdu PUTATIVE
THIOESTERASE
(Syntrophus
aciditrophicus) 		4 / 8 THR A 136
TYR A 123
LEU A 145
MET A 139
 None
 1.46A 1uw6A-3hduA:
undetectable
1uw6B-3hduA:
undetectable		 1uw6A-3hduA:
20.56
1uw6B-3hduA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UW6_D_NCTD1208_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 3hdu PUTATIVE
THIOESTERASE
(Syntrophus
aciditrophicus) 		4 / 8 THR A 136
TYR A 123
LEU A 145
MET A 139
 None
 1.48A 1uw6D-3hduA:
undetectable
1uw6E-3hduA:
undetectable		 1uw6D-3hduA:
20.56
1uw6E-3hduA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UW6_G_NCTG1206_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 3hdu PUTATIVE
THIOESTERASE
(Syntrophus
aciditrophicus) 		4 / 8 THR A 136
TYR A 123
LEU A 145
MET A 139
 None
 1.46A 1uw6G-3hduA:
undetectable
1uw6H-3hduA:
undetectable		 1uw6G-3hduA:
20.56
1uw6H-3hduA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UW6_P_NCTP1206_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 3hdu PUTATIVE
THIOESTERASE
(Syntrophus
aciditrophicus) 		4 / 8 THR A 136
TYR A 123
LEU A 145
MET A 139
 None
 1.46A 1uw6P-3hduA:
undetectable
1uw6Q-3hduA:
undetectable		 1uw6P-3hduA:
20.56
1uw6Q-3hduA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UW6_T_NCTT1208_1
(ACETYLCHOLINE-BINDIN
G PROTEIN)		 3hdu PUTATIVE
THIOESTERASE
(Syntrophus
aciditrophicus) 		4 / 8 LEU A 145
MET A 139
THR A 136
TYR A 123
 None
 1.45A 1uw6P-3hduA:
undetectable
1uw6T-3hduA:
undetectable		 1uw6P-3hduA:
20.56
1uw6T-3hduA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZQ9_A_SAMA4000_1
(PROBABLE
DIMETHYLADENOSINE
TRANSFERASE)		 3hdu PUTATIVE
THIOESTERASE
(Syntrophus
aciditrophicus) 		3 / 3 GLY A  30
GLU A  46
ASN A  26
 None
 0.67A 1zq9A-3hduA:
undetectable		 1zq9A-3hduA:
18.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_B_SVRB512_2
(PHOSPHOLIPASE A2)		 3hdu PUTATIVE
THIOESTERASE
(Syntrophus
aciditrophicus) 		4 / 7 VAL A 119
ILE A  65
GLY A  62
ARG A  58
 None
 0.87A 3bjwB-3hduA:
undetectable		 3bjwB-3hduA:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FL9_C_TOPC200_1
(DIHYDROFOLATE
REDUCTASE (DHFR))		 3hdu PUTATIVE
THIOESTERASE
(Syntrophus
aciditrophicus) 		5 / 11 MET A  47
VAL A  64
ILE A 146
LEU A 138
PHE A 118
 None
 1.24A 3fl9C-3hduA:
undetectable		 3fl9C-3hduA:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FL9_D_TOPD200_1
(DIHYDROFOLATE
REDUCTASE (DHFR))		 3hdu PUTATIVE
THIOESTERASE
(Syntrophus
aciditrophicus) 		5 / 9 MET A  47
VAL A  64
ILE A 146
LEU A 138
PHE A 118
 None
 1.32A 3fl9D-3hduA:
undetectable		 3fl9D-3hduA:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M6W_A_SAMA465_0
(RRNA METHYLASE)		 3hdu PUTATIVE
THIOESTERASE
(Syntrophus
aciditrophicus) 		5 / 12 ALA A  68
GLY A  63
GLY A  62
VAL A  41
LEU A  43
 None
 1.02A 3m6wA-3hduA:
undetectable		 3m6wA-3hduA:
15.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LBT_A_6T0A303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 3hdu PUTATIVE
THIOESTERASE
(Syntrophus
aciditrophicus) 		5 / 10 PHE A  45
ILE A  69
PHE A 118
GLY A  63
GLY A  62
 None
 1.30A 5lbtA-3hduA:
undetectable
5lbtB-3hduA:
undetectable		 5lbtA-3hduA:
23.32
5lbtB-3hduA:
23.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MQT_C_STIC302_1
(DEOXYCYTIDINE KINASE)		 3hdu PUTATIVE
THIOESTERASE
(Syntrophus
aciditrophicus) 		5 / 12 GLU A  20
VAL A  33
PRO A  38
GLU A  83
LEU A  11
 None
 1.27A 5mqtC-3hduA:
undetectable		 5mqtC-3hduA:
21.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_A_7V7A202_1
(ENDO-1,4-BETA-XYLANA
SE A)		 3hdu PUTATIVE
THIOESTERASE
(Syntrophus
aciditrophicus) 		5 / 12 PHE A  35
SER A  37
VAL A  41
ALA A  77
ALA A  76
 None
 1.33A 5tzoA-3hduA:
undetectable		 5tzoA-3hduA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TZO_C_7V7C201_1
(ENDO-1,4-BETA-XYLANA
SE A)		 3hdu PUTATIVE
THIOESTERASE
(Syntrophus
aciditrophicus) 		5 / 12 PHE A  35
SER A  37
VAL A  41
ALA A  77
ALA A  76
 None
 1.33A 5tzoC-3hduA:
undetectable		 5tzoC-3hduA:
19.70