SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3hdv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AQI_A_CHDA2_0
(FERROCHELATASE)		 3hdv RESPONSE REGULATOR
(Pseudomonas
putida) 		4 / 6 ARG A 136
PRO A 125
GLY A 128
MET A 123
 None
 1.36A 3aqiA-3hdvA:
5.0		 3aqiA-3hdvA:
17.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6R_B_CRNB603_1
(CREATINE KINASE
B-TYPE)		 3hdv RESPONSE REGULATOR
(Pseudomonas
putida) 		4 / 6 THR A 119
VAL A 147
GLU A 156
SER A 149
 None
 1.24A 3b6rB-3hdvA:
undetectable		 3b6rB-3hdvA:
16.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KP6_B_SALB3003_1
(TRANSCRIPTIONAL
REGULATOR TCAR)		 3hdv RESPONSE REGULATOR
(Pseudomonas
putida) 		4 / 6 ILE A 146
VAL A 182
LEU A 179
LEU A 175
 None
 0.91A 3kp6A-3hdvA:
undetectable
3kp6B-3hdvA:
undetectable		 3kp6A-3hdvA:
21.74
3kp6B-3hdvA:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K4Y_A_ACTA502_0
(RNA-DEPENDENT RNA
POLYMERASE)		 3hdv RESPONSE REGULATOR
(Pseudomonas
putida) 		4 / 5 LYS A 187
LEU A 186
GLU A 185
LEU A 116
 None
 0.89A 4k4yA-3hdvA:
undetectable		 4k4yA-3hdvA:
16.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K4Y_E_ACTE503_0
(RNA-DEPENDENT RNA
POLYMERASE)		 3hdv RESPONSE REGULATOR
(Pseudomonas
putida) 		4 / 4 LYS A 187
LEU A 186
GLU A 185
LEU A 116
 None
 0.92A 4k4yE-3hdvA:
undetectable		 4k4yE-3hdvA:
16.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K4Y_I_ACTI503_0
(RNA-DEPENDENT RNA
POLYMERASE)		 3hdv RESPONSE REGULATOR
(Pseudomonas
putida) 		4 / 5 LYS A 187
LEU A 186
GLU A 185
LEU A 116
 None
 0.91A 4k4yI-3hdvA:
undetectable		 4k4yI-3hdvA:
16.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MK4_B_CHDB504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3hdv RESPONSE REGULATOR
(Pseudomonas
putida) 		3 / 3 LEU A 131
ILE A 132
ARG A 136
 None
 0.61A 4mk4B-3hdvA:
3.9		 4mk4B-3hdvA:
19.56