SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3hdy'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D4Y_A_TPVA501_2
(PROTEIN (HIV-1
PROTEASE))		 3hdy UDP-GALACTOPYRANOSE
MUTASE
(Deinococcus
radiodurans) 		5 / 8 LEU A 230
ALA A  49
ILE A 256
VAL A 237
ILE A 235
 None
 0.81A 1d4yB-3hdyA:
undetectable		 1d4yB-3hdyA:
11.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DHF_A_FOLA187_0
(DIHYDROFOLATE
REDUCTASE)		 3hdy UDP-GALACTOPYRANOSE
MUTASE
(Deinococcus
radiodurans) 		5 / 12 ILE A 256
ALA A 380
GLN A  53
ILE A 235
ASN A 234
 None
 1.19A 1dhfA-3hdyA:
undetectable		 1dhfA-3hdyA:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HSG_B_MK1B902_2
(HIV-1 PROTEASE)		 3hdy UDP-GALACTOPYRANOSE
MUTASE
(Deinococcus
radiodurans) 		5 / 12 GLY A  38
ALA A  37
VAL A 237
VAL A  55
ILE A  57
 FAD  A 450 (-3.3A)
None
None
None
None
 0.85A 1hsgB-3hdyA:
undetectable		 1hsgB-3hdyA:
12.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K6C_B_MK1B902_1
(POL POLYPROTEIN)		 3hdy UDP-GALACTOPYRANOSE
MUTASE
(Deinococcus
radiodurans) 		5 / 10 LEU A  33
VAL A 237
ILE A  64
GLY A  65
GLY A  38
 None
None
None
None
FAD  A 450 (-3.3A)
 1.05A 1k6cA-3hdyA:
undetectable		 1k6cA-3hdyA:
13.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SDT_B_MK1B902_2
(PROTEASE RETROPEPSIN)		 3hdy UDP-GALACTOPYRANOSE
MUTASE
(Deinococcus
radiodurans) 		5 / 12 GLY A  38
ALA A  37
VAL A 237
VAL A  55
ILE A  57
 FAD  A 450 (-3.3A)
None
None
None
None
 0.98A 1sdtB-3hdyA:
undetectable		 1sdtB-3hdyA:
13.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVV_A_MK1A901_3
(POL POLYPROTEIN)		 3hdy UDP-GALACTOPYRANOSE
MUTASE
(Deinococcus
radiodurans) 		5 / 12 GLY A  38
ALA A  37
VAL A 237
VAL A  55
ILE A  57
 FAD  A 450 (-3.3A)
None
None
None
None
 0.77A 2avvB-3hdyA:
undetectable		 2avvB-3hdyA:
13.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BPX_B_MK1B902_2
(HIV-1 PROTEASE)		 3hdy UDP-GALACTOPYRANOSE
MUTASE
(Deinococcus
radiodurans) 		5 / 12 GLY A  38
ALA A  37
VAL A 237
VAL A  55
ILE A  57
 FAD  A 450 (-3.3A)
None
None
None
None
 0.81A 2bpxB-3hdyA:
undetectable		 2bpxB-3hdyA:
12.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		 3hdy UDP-GALACTOPYRANOSE
MUTASE
(Deinococcus
radiodurans) 		5 / 12 LEU A 387
LEU A  48
ALA A  45
ILE A  34
ALA A 380
 None
 1.13A 2bxpA-3hdyA:
undetectable		 2bxpA-3hdyA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F80_B_017B301_2
(POL POLYPROTEIN)		 3hdy UDP-GALACTOPYRANOSE
MUTASE
(Deinococcus
radiodurans) 		5 / 12 GLY A  38
ALA A  37
VAL A 237
VAL A  55
ILE A  57
 FAD  A 450 (-3.3A)
None
None
None
None
 0.81A 2f80B-3hdyA:
undetectable		 2f80B-3hdyA:
13.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F81_A_017A302_1
(POL POLYPROTEIN)		 3hdy UDP-GALACTOPYRANOSE
MUTASE
(Deinococcus
radiodurans) 		5 / 12 GLY A  38
ALA A  37
VAL A 237
VAL A  55
ILE A  57
 FAD  A 450 (-3.3A)
None
None
None
None
 0.90A 2f81A-3hdyA:
undetectable		 2f81A-3hdyA:
13.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F81_A_017A302_2
(POL POLYPROTEIN)		 3hdy UDP-GALACTOPYRANOSE
MUTASE
(Deinococcus
radiodurans) 		5 / 12 GLY A  38
ALA A  37
VAL A 237
VAL A  55
ILE A  57
 FAD  A 450 (-3.3A)
None
None
None
None
 0.87A 2f81B-3hdyA:
undetectable		 2f81B-3hdyA:
13.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F81_A_017A302_2
(POL POLYPROTEIN)		 3hdy UDP-GALACTOPYRANOSE
MUTASE
(Deinococcus
radiodurans) 		5 / 12 LEU A 230
ALA A  49
ILE A 256
VAL A 237
ILE A 235
 None
 0.91A 2f81B-3hdyA:
undetectable		 2f81B-3hdyA:
13.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F8G_B_017B401_2
(POL POLYPROTEIN)		 3hdy UDP-GALACTOPYRANOSE
MUTASE
(Deinococcus
radiodurans) 		5 / 12 GLY A  38
ALA A  37
VAL A 237
VAL A  55
ILE A  57
 FAD  A 450 (-3.3A)
None
None
None
None
 0.88A 2f8gB-3hdyA:
undetectable		 2f8gB-3hdyA:
13.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HS2_A_017A201_2
(PROTEASE)		 3hdy UDP-GALACTOPYRANOSE
MUTASE
(Deinococcus
radiodurans) 		5 / 12 LEU A 230
ALA A  49
ILE A 256
VAL A 237
ILE A 235
 None
 0.94A 2hs2B-3hdyA:
undetectable		 2hs2B-3hdyA:
13.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IEN_B_017B402_1
(PROTEASE)		 3hdy UDP-GALACTOPYRANOSE
MUTASE
(Deinococcus
radiodurans) 		5 / 12 GLY A  38
ALA A  37
VAL A 237
VAL A  55
ILE A  57
 FAD  A 450 (-3.3A)
None
None
None
None
 0.91A 2ienA-3hdyA:
undetectable		 2ienA-3hdyA:
13.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IEN_B_017B402_2
(PROTEASE)		 3hdy UDP-GALACTOPYRANOSE
MUTASE
(Deinococcus
radiodurans) 		5 / 12 GLY A  38
ALA A  37
VAL A 237
VAL A  55
ILE A  57
 FAD  A 450 (-3.3A)
None
None
None
None
 0.86A 2ienB-3hdyA:
undetectable		 2ienB-3hdyA:
13.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2M2O_B_DHIB24_0
(INSULIN B CHAIN)		 3hdy UDP-GALACTOPYRANOSE
MUTASE
(Deinococcus
radiodurans) 		4 / 6 ARG A 244
PHE A 264
PRO A 260
THR A 258
 FAD  A 450 ( 3.9A)
None
None
None
 1.25A 2m2oB-3hdyA:
undetectable		 2m2oB-3hdyA:
7.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4K_A_DR7A301_2
(PROTEASE)		 3hdy UDP-GALACTOPYRANOSE
MUTASE
(Deinococcus
radiodurans) 		5 / 12 GLY A  38
ALA A  37
VAL A 237
VAL A  55
ILE A  57
 FAD  A 450 (-3.3A)
None
None
None
None
 0.83A 2o4kB-3hdyA:
undetectable		 2o4kB-3hdyA:
11.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4L_A_TPVA403_2
(PROTEASE)		 3hdy UDP-GALACTOPYRANOSE
MUTASE
(Deinococcus
radiodurans) 		5 / 12 GLY A  38
ALA A  37
VAL A 237
VAL A  55
ILE A  57
 FAD  A 450 (-3.3A)
None
None
None
None
 0.77A 2o4lB-3hdyA:
undetectable		 2o4lB-3hdyA:
12.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4P_A_TPVA300_2
(PROTEASE)		 3hdy UDP-GALACTOPYRANOSE
MUTASE
(Deinococcus
radiodurans) 		5 / 9 LEU A 230
ALA A  49
ILE A 256
VAL A 237
ILE A 235
 None
 0.93A 2o4pB-3hdyA:
undetectable		 2o4pB-3hdyA:
11.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2O4S_A_AB1A400_1
(PROTEASE)		 3hdy UDP-GALACTOPYRANOSE
MUTASE
(Deinococcus
radiodurans) 		5 / 12 GLY A  38
ALA A  37
VAL A 237
VAL A  55
ILE A  57
 FAD  A 450 (-3.3A)
None
None
None
None
 0.85A 2o4sA-3hdyA:
undetectable		 2o4sA-3hdyA:
11.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PYM_A_1UNA1001_1
(PROTEASE RETROPEPSIN)		 3hdy UDP-GALACTOPYRANOSE
MUTASE
(Deinococcus
radiodurans) 		5 / 12 GLY A  38
ALA A  37
VAL A 237
VAL A  55
ILE A  57
 FAD  A 450 (-3.3A)
None
None
None
None
 0.90A 2pymA-3hdyA:
undetectable		 2pymA-3hdyA:
11.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PYM_A_1UNA1001_2
(PROTEASE RETROPEPSIN)		 3hdy UDP-GALACTOPYRANOSE
MUTASE
(Deinococcus
radiodurans) 		5 / 12 GLY A  38
ALA A  37
VAL A 237
VAL A  55
ILE A  57
 FAD  A 450 (-3.3A)
None
None
None
None
 0.90A 2pymB-3hdyA:
undetectable		 2pymB-3hdyA:
11.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PYN_A_1UNA1001_1
(PROTEASE RETROPEPSIN)		 3hdy UDP-GALACTOPYRANOSE
MUTASE
(Deinococcus
radiodurans) 		5 / 12 GLY A  38
ALA A  37
VAL A 237
VAL A  55
ILE A  57
 FAD  A 450 (-3.3A)
None
None
None
None
 0.90A 2pynA-3hdyA:
undetectable		 2pynA-3hdyA:
11.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PYN_A_1UNA1001_2
(PROTEASE RETROPEPSIN)		 3hdy UDP-GALACTOPYRANOSE
MUTASE
(Deinococcus
radiodurans) 		5 / 12 GLY A  38
ALA A  37
VAL A 237
VAL A  55
ILE A  57
 FAD  A 450 (-3.3A)
None
None
None
None
 0.90A 2pynB-3hdyA:
undetectable		 2pynB-3hdyA:
11.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q63_A_1UNA1001_1
(PROTEASE RETROPEPSIN)		 3hdy UDP-GALACTOPYRANOSE
MUTASE
(Deinococcus
radiodurans) 		5 / 12 GLY A  38
ALA A  37
VAL A 237
VAL A  55
ILE A  57
 FAD  A 450 (-3.3A)
None
None
None
None
 0.88A 2q63A-3hdyA:
undetectable		 2q63A-3hdyA:
11.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q63_A_1UNA1001_3
(PROTEASE RETROPEPSIN)		 3hdy UDP-GALACTOPYRANOSE
MUTASE
(Deinococcus
radiodurans) 		5 / 12 GLY A  38
ALA A  37
VAL A 237
VAL A  55
ILE A  57
 FAD  A 450 (-3.3A)
None
None
None
None
 0.87A 2q63B-3hdyA:
undetectable		 2q63B-3hdyA:
11.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q64_B_1UNB1001_3
(PROTEASE RETROPEPSIN)		 3hdy UDP-GALACTOPYRANOSE
MUTASE
(Deinococcus
radiodurans) 		5 / 12 GLY A  38
ALA A  37
VAL A 237
VAL A  55
ILE A  57
 FAD  A 450 (-3.3A)
None
None
None
None
 0.84A 2q64B-3hdyA:
undetectable		 2q64B-3hdyA:
11.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QAK_A_1UNA1001_3
(PROTEASE RETROPEPSIN)		 3hdy UDP-GALACTOPYRANOSE
MUTASE
(Deinococcus
radiodurans) 		5 / 12 GLY A  38
ALA A  37
VAL A 237
VAL A  55
ILE A  57
 FAD  A 450 (-3.3A)
None
None
None
None
 0.85A 2qakB-3hdyA:
undetectable		 2qakB-3hdyA:
11.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QAK_A_1UNA1001_3
(PROTEASE RETROPEPSIN)		 3hdy UDP-GALACTOPYRANOSE
MUTASE
(Deinococcus
radiodurans) 		5 / 12 LEU A 230
ALA A  49
ILE A 256
VAL A 237
ILE A 235
 None
 0.98A 2qakB-3hdyA:
undetectable		 2qakB-3hdyA:
11.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHC_B_AB1B9001_2
(PROTEASE RETROPEPSIN)		 3hdy UDP-GALACTOPYRANOSE
MUTASE
(Deinococcus
radiodurans) 		5 / 12 GLY A  38
ALA A  37
VAL A 237
VAL A  55
ILE A  57
 FAD  A 450 (-3.3A)
None
None
None
None
 0.95A 2qhcB-3hdyA:
undetectable		 2qhcB-3hdyA:
12.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UZ2_A_ACTA1123_0
(XENAVIDIN)		 3hdy UDP-GALACTOPYRANOSE
MUTASE
(Deinococcus
radiodurans) 		4 / 7 LEU A 191
SER A 159
THR A 196
VAL A 195
 None
None
GDU  A 500 (-4.6A)
GDU  A 500 (-4.9A)
 1.17A 2uz2A-3hdyA:
undetectable		 2uz2A-3hdyA:
15.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YQZ_A_SAMA301_0
(HYPOTHETICAL PROTEIN
TTHA0223)		 3hdy UDP-GALACTOPYRANOSE
MUTASE
(Deinococcus
radiodurans) 		5 / 12 GLY A  41
GLY A  36
ILE A  64
LEU A  44
ALA A 380
 None
FAD  A 450 (-3.4A)
None
None
None
 0.91A 2yqzA-3hdyA:
undetectable		 2yqzA-3hdyA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YQZ_B_SAMB401_0
(HYPOTHETICAL PROTEIN
TTHA0223)		 3hdy UDP-GALACTOPYRANOSE
MUTASE
(Deinococcus
radiodurans) 		5 / 12 GLY A  41
GLY A  36
ILE A  64
LEU A  44
ALA A 380
 None
FAD  A 450 (-3.4A)
None
None
None
 0.91A 2yqzB-3hdyA:
undetectable		 2yqzB-3hdyA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z54_A_AB1A200_1
(HIV-1 PROTEASE)		 3hdy UDP-GALACTOPYRANOSE
MUTASE
(Deinococcus
radiodurans) 		5 / 12 GLY A  38
ALA A  37
VAL A 237
VAL A  55
ILE A  57
 FAD  A 450 (-3.3A)
None
None
None
None
 0.85A 2z54A-3hdyA:
undetectable		 2z54A-3hdyA:
11.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Z54_A_AB1A200_2
(HIV-1 PROTEASE)		 3hdy UDP-GALACTOPYRANOSE
MUTASE
(Deinococcus
radiodurans) 		5 / 12 GLY A  38
ALA A  37
VAL A 237
VAL A  55
ILE A  57
 FAD  A 450 (-3.3A)
None
None
None
None
 0.93A 2z54B-3hdyA:
undetectable		 2z54B-3hdyA:
11.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BVB_B_017B401_1
(PROTEASE
(RETROPEPSIN))		 3hdy UDP-GALACTOPYRANOSE
MUTASE
(Deinococcus
radiodurans) 		5 / 12 GLY A  38
ALA A  37
VAL A 237
VAL A  55
ILE A  57
 FAD  A 450 (-3.3A)
None
None
None
None
 0.86A 3bvbA-3hdyA:
undetectable		 3bvbA-3hdyA:
12.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BVB_B_017B401_2
(PROTEASE
(RETROPEPSIN))		 3hdy UDP-GALACTOPYRANOSE
MUTASE
(Deinococcus
radiodurans) 		5 / 12 GLY A  38
ALA A  37
VAL A 237
VAL A  55
ILE A  57
 FAD  A 450 (-3.3A)
None
None
None
None
 0.87A 3bvbB-3hdyA:
undetectable		 3bvbB-3hdyA:
12.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CYW_A_017A201_1
(HIV-1 PROTEASE)		 3hdy UDP-GALACTOPYRANOSE
MUTASE
(Deinococcus
radiodurans) 		5 / 12 GLY A  38
ALA A  37
VAL A 237
VAL A  55
ILE A  57
 FAD  A 450 (-3.3A)
None
None
None
None
 0.85A 3cywA-3hdyA:
undetectable		 3cywA-3hdyA:
13.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CYW_A_017A201_2
(HIV-1 PROTEASE)		 3hdy UDP-GALACTOPYRANOSE
MUTASE
(Deinococcus
radiodurans) 		5 / 12 GLY A  38
ALA A  37
VAL A 237
VAL A  55
ILE A  57
 FAD  A 450 (-3.3A)
None
None
None
None
 0.86A 3cywB-3hdyA:
undetectable		 3cywB-3hdyA:
13.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D20_A_017A201_2
(HIV-1 PROTEASE)		 3hdy UDP-GALACTOPYRANOSE
MUTASE
(Deinococcus
radiodurans) 		5 / 12 GLY A  38
ALA A  37
VAL A 237
VAL A  55
ILE A  57
 FAD  A 450 (-3.3A)
None
None
None
None
 0.80A 3d20B-3hdyA:
undetectable		 3d20B-3hdyA:
13.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL1_A_DR7A100_2
(PROTEASE)		 3hdy UDP-GALACTOPYRANOSE
MUTASE
(Deinococcus
radiodurans) 		5 / 12 GLY A  38
ALA A  37
VAL A 237
VAL A  55
ILE A  57
 FAD  A 450 (-3.3A)
None
None
None
None
 0.79A 3el1B-3hdyA:
undetectable		 3el1B-3hdyA:
11.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM3_B_478B200_1
(PROTEASE)		 3hdy UDP-GALACTOPYRANOSE
MUTASE
(Deinococcus
radiodurans) 		5 / 10 GLY A  38
ALA A  37
VAL A 237
VAL A  55
ILE A  57
 FAD  A 450 (-3.3A)
None
None
None
None
 0.89A 3em3A-3hdyA:
undetectable		 3em3A-3hdyA:
12.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G2O_B_SAMB600_0
(PCZA361.24)		 3hdy UDP-GALACTOPYRANOSE
MUTASE
(Deinococcus
radiodurans) 		6 / 12 GLU A  46
ALA A  49
LEU A  48
ASP A  31
SER A 231
SER A 232
 None
 1.31A 3g2oB-3hdyA:
2.1		 3g2oB-3hdyA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IJD_A_C2FA314_0
(UNCHARACTERIZED
PROTEIN)		 3hdy UDP-GALACTOPYRANOSE
MUTASE
(Deinococcus
radiodurans) 		5 / 12 THR A 360
LEU A 387
GLY A  52
ILE A 235
LEU A  44
 None
 0.98A 3ijdA-3hdyA:
undetectable		 3ijdA-3hdyA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JVY_B_017B401_1
(GAG-POL POLYPROTEIN)		 3hdy UDP-GALACTOPYRANOSE
MUTASE
(Deinococcus
radiodurans) 		5 / 12 GLY A  38
ALA A  37
VAL A 237
VAL A  55
ILE A  57
 FAD  A 450 (-3.3A)
None
None
None
None
 0.88A 3jvyA-3hdyA:
undetectable		 3jvyA-3hdyA:
13.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JVY_B_017B401_1
(GAG-POL POLYPROTEIN)		 3hdy UDP-GALACTOPYRANOSE
MUTASE
(Deinococcus
radiodurans) 		5 / 12 LEU A 230
ALA A  49
ILE A 256
VAL A 237
ILE A 235
 None
 0.95A 3jvyA-3hdyA:
undetectable		 3jvyA-3hdyA:
13.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JVY_B_017B401_2
(GAG-POL POLYPROTEIN)		 3hdy UDP-GALACTOPYRANOSE
MUTASE
(Deinococcus
radiodurans) 		5 / 12 GLY A  38
ALA A  37
VAL A 237
VAL A  55
ILE A  57
 FAD  A 450 (-3.3A)
None
None
None
None
 0.84A 3jvyB-3hdyA:
undetectable		 3jvyB-3hdyA:
13.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JW2_A_017A401_1
(GAG-POL POLYPROTEIN)		 3hdy UDP-GALACTOPYRANOSE
MUTASE
(Deinococcus
radiodurans) 		5 / 12 GLY A  38
ALA A  37
VAL A 237
VAL A  55
ILE A  57
 FAD  A 450 (-3.3A)
None
None
None
None
 0.87A 3jw2A-3hdyA:
undetectable		 3jw2A-3hdyA:
13.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_B_ROCB201_3
(HIV-1 PROTEASE)		 3hdy UDP-GALACTOPYRANOSE
MUTASE
(Deinococcus
radiodurans) 		5 / 12 GLY A  38
ALA A  37
VAL A 237
VAL A  55
ILE A  57
 FAD  A 450 (-3.3A)
None
None
None
None
 0.86A 3k4vB-3hdyA:
undetectable		 3k4vB-3hdyA:
13.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_D_ROCD201_1
(HIV-1 PROTEASE)		 3hdy UDP-GALACTOPYRANOSE
MUTASE
(Deinococcus
radiodurans) 		5 / 12 LEU A 230
ALA A  49
ILE A 256
VAL A 237
ILE A 235
 None
 1.00A 3k4vC-3hdyA:
undetectable		 3k4vC-3hdyA:
13.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LZS_A_017A200_1
(HIV-1 PROTEASE)		 3hdy UDP-GALACTOPYRANOSE
MUTASE
(Deinococcus
radiodurans) 		5 / 12 GLY A  38
ALA A  37
VAL A 237
VAL A  55
ILE A  57
 FAD  A 450 (-3.3A)
None
None
None
None
 0.88A 3lzsA-3hdyA:
undetectable		 3lzsA-3hdyA:
14.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LZS_A_017A200_2
(HIV-1 PROTEASE)		 3hdy UDP-GALACTOPYRANOSE
MUTASE
(Deinococcus
radiodurans) 		5 / 12 GLY A  38
ALA A  37
VAL A 237
VAL A  55
ILE A  57
 FAD  A 450 (-3.3A)
None
None
None
None
 0.91A 3lzsB-3hdyA:
undetectable		 3lzsB-3hdyA:
14.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LZU_A_017A200_1
(HIV-1 PROTEASE)		 3hdy UDP-GALACTOPYRANOSE
MUTASE
(Deinococcus
radiodurans) 		5 / 12 GLY A  38
ALA A  37
VAL A 237
VAL A  55
ILE A  57
 FAD  A 450 (-3.3A)
None
None
None
None
 0.88A 3lzuA-3hdyA:
undetectable		 3lzuA-3hdyA:
12.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LZU_A_017A200_2
(HIV-1 PROTEASE)		 3hdy UDP-GALACTOPYRANOSE
MUTASE
(Deinococcus
radiodurans) 		5 / 12 GLY A  38
ALA A  37
VAL A 237
VAL A  55
ILE A  57
 FAD  A 450 (-3.3A)
None
None
None
None
 0.88A 3lzuB-3hdyA:
undetectable		 3lzuB-3hdyA:
12.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDT_D_ROCD100_1
(PROTEASE)		 3hdy UDP-GALACTOPYRANOSE
MUTASE
(Deinococcus
radiodurans) 		5 / 12 LEU A 230
ALA A  49
ILE A 256
VAL A 237
ILE A 235
 None
 0.97A 3ndtC-3hdyA:
undetectable		 3ndtC-3hdyA:
13.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDT_D_ROCD100_2
(PROTEASE)		 3hdy UDP-GALACTOPYRANOSE
MUTASE
(Deinococcus
radiodurans) 		5 / 12 GLY A  38
ALA A  37
VAL A 237
VAL A  55
ILE A  57
 FAD  A 450 (-3.3A)
None
None
None
None
 0.86A 3ndtD-3hdyA:
undetectable		 3ndtD-3hdyA:
13.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDW_A_RITA100_1
(PROTEASE)		 3hdy UDP-GALACTOPYRANOSE
MUTASE
(Deinococcus
radiodurans) 		5 / 12 GLY A  38
ALA A  37
VAL A 237
VAL A  55
ILE A  57
 FAD  A 450 (-3.3A)
None
None
None
None
 0.79A 3ndwA-3hdyA:
undetectable		 3ndwA-3hdyA:
13.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU6_B_478B401_2
(PROTEASE)		 3hdy UDP-GALACTOPYRANOSE
MUTASE
(Deinococcus
radiodurans) 		5 / 10 GLY A  38
ALA A  37
VAL A 237
VAL A  55
ILE A  57
 FAD  A 450 (-3.3A)
None
None
None
None
 0.88A 3nu6B-3hdyA:
undetectable		 3nu6B-3hdyA:
13.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU6_B_478B401_2
(PROTEASE)		 3hdy UDP-GALACTOPYRANOSE
MUTASE
(Deinococcus
radiodurans) 		5 / 10 LEU A 230
ALA A  49
ILE A 256
VAL A 237
ILE A 235
 None
 0.93A 3nu6B-3hdyA:
undetectable		 3nu6B-3hdyA:
13.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU7_A_SAMA300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 3hdy UDP-GALACTOPYRANOSE
MUTASE
(Deinococcus
radiodurans) 		5 / 12 TYR A  69
TYR A  82
ALA A  37
GLY A  66
LEU A 230
 None
None
None
FAD  A 450 (-3.4A)
None
 1.12A 3ou7A-3hdyA:
undetectable		 3ou7A-3hdyA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU7_D_SAMD300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 3hdy UDP-GALACTOPYRANOSE
MUTASE
(Deinococcus
radiodurans) 		5 / 12 TYR A  69
TYR A  82
ALA A  37
GLY A  66
LEU A 230
 None
None
None
FAD  A 450 (-3.4A)
None
 1.13A 3ou7D-3hdyA:
undetectable		 3ou7D-3hdyA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXC_A_ROCA401_1
(PROTEASE)		 3hdy UDP-GALACTOPYRANOSE
MUTASE
(Deinococcus
radiodurans) 		5 / 12 GLY A  38
ALA A  37
VAL A 237
VAL A  55
ILE A  57
 FAD  A 450 (-3.3A)
None
None
None
None
 0.83A 3oxcA-3hdyA:
undetectable		 3oxcA-3hdyA:
13.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PWM_B_017B402_1
(PROTEASE)		 3hdy UDP-GALACTOPYRANOSE
MUTASE
(Deinococcus
radiodurans) 		5 / 12 GLY A  38
ALA A  37
VAL A 237
VAL A  55
ILE A  57
 FAD  A 450 (-3.3A)
None
None
None
None
 0.83A 3pwmA-3hdyA:
undetectable		 3pwmA-3hdyA:
13.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PWM_B_017B402_2
(PROTEASE)		 3hdy UDP-GALACTOPYRANOSE
MUTASE
(Deinococcus
radiodurans) 		5 / 12 GLY A  38
ALA A  37
VAL A 237
VAL A  55
ILE A  57
 FAD  A 450 (-3.3A)
None
None
None
None
 0.87A 3pwmB-3hdyA:
undetectable		 3pwmB-3hdyA:
13.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PWR_A_ROCA401_3
(PROTEASE)		 3hdy UDP-GALACTOPYRANOSE
MUTASE
(Deinococcus
radiodurans) 		5 / 12 GLY A  38
ALA A  37
VAL A 237
VAL A  55
ILE A  57
 FAD  A 450 (-3.3A)
None
None
None
None
 0.84A 3pwrB-3hdyA:
undetectable		 3pwrB-3hdyA:
13.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKW_B_017B401_1
(PROTEASE)		 3hdy UDP-GALACTOPYRANOSE
MUTASE
(Deinococcus
radiodurans) 		5 / 12 GLY A  38
ALA A  37
VAL A 237
VAL A  55
ILE A  57
 FAD  A 450 (-3.3A)
None
None
None
None
 0.86A 3tkwA-3hdyA:
undetectable		 3tkwA-3hdyA:
14.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TKW_B_017B401_2
(PROTEASE)		 3hdy UDP-GALACTOPYRANOSE
MUTASE
(Deinococcus
radiodurans) 		5 / 12 GLY A  38
ALA A  37
VAL A 237
VAL A  55
ILE A  57
 FAD  A 450 (-3.3A)
None
None
None
None
 0.82A 3tkwB-3hdyA:
undetectable		 3tkwB-3hdyA:
14.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TL9_A_ROCA401_3
(PROTEASE)		 3hdy UDP-GALACTOPYRANOSE
MUTASE
(Deinococcus
radiodurans) 		5 / 12 GLY A  38
ALA A  37
VAL A 237
VAL A  55
ILE A  57
 FAD  A 450 (-3.3A)
None
None
None
None
 0.87A 3tl9B-3hdyA:
undetectable		 3tl9B-3hdyA:
14.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WFA_B_EDTB802_0
(ALPHA-GLUCOSIDASE)		 3hdy UDP-GALACTOPYRANOSE
MUTASE
(Deinococcus
radiodurans) 		4 / 6 ARG A 198
ASP A 374
ASN A 372
TYR A 370
 GDU  A 500 (-3.8A)
None
FAD  A 450 ( 4.3A)
GDU  A 500 (-4.8A)
 1.28A 3wfaA-3hdyA:
undetectable
3wfaB-3hdyA:
undetectable		 3wfaA-3hdyA:
20.03
3wfaB-3hdyA:
20.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JEC_B_478B401_1
(HIV-1 PROTEASE)		 3hdy UDP-GALACTOPYRANOSE
MUTASE
(Deinococcus
radiodurans) 		5 / 12 GLY A  38
ALA A  37
VAL A 237
VAL A  55
ILE A  57
 FAD  A 450 (-3.3A)
None
None
None
None
 0.82A 4jecA-3hdyA:
undetectable		 4jecA-3hdyA:
13.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLM_A_198A1001_2
(ANDROGEN RECEPTOR)		 3hdy UDP-GALACTOPYRANOSE
MUTASE
(Deinococcus
radiodurans) 		4 / 6 ASN A 228
MET A 373
ILE A 235
VAL A 237
 None
FAD  A 450 (-4.4A)
None
None
 0.79A 4olmA-3hdyA:
undetectable		 4olmA-3hdyA:
18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q1Y_A_017A106_2
(ASPARTYL PROTEASE)		 3hdy UDP-GALACTOPYRANOSE
MUTASE
(Deinococcus
radiodurans) 		5 / 12 LEU A 230
ALA A  49
ILE A 256
VAL A 237
ILE A 235
 None
 0.97A 4q1yB-3hdyA:
undetectable		 4q1yB-3hdyA:
11.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XE5_A_OBNA1104_2
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 3hdy UDP-GALACTOPYRANOSE
MUTASE
(Deinococcus
radiodurans) 		4 / 6 PRO A 298
ILE A 122
VAL A 163
THR A 180
 None
GDU  A 500 ( 4.3A)
None
GDU  A 500 (-3.2A)
 1.14A 4xe5A-3hdyA:
undetectable		 4xe5A-3hdyA:
16.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YIA_B_IMNB401_2
(THYROXINE-BINDING
GLOBULIN)		 3hdy UDP-GALACTOPYRANOSE
MUTASE
(Deinococcus
radiodurans) 		3 / 3 LEU A 277
ARG A 328
ARG A 275
 None
 0.97A 4yiaB-3hdyA:
undetectable		 4yiaB-3hdyA:
5.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXA_A_ADNA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 3hdy UDP-GALACTOPYRANOSE
MUTASE
(Deinococcus
radiodurans) 		4 / 5 GLU A 103
THR A 102
THR A 313
HIS A 317
 None
 1.22A 5axaA-3hdyA:
2.1		 5axaA-3hdyA:
23.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXA_C_ADNC502_2
(ADENOSYLHOMOCYSTEINA
SE)		 3hdy UDP-GALACTOPYRANOSE
MUTASE
(Deinococcus
radiodurans) 		4 / 5 GLU A 103
THR A 102
THR A 313
HIS A 317
 None
 1.22A 5axaC-3hdyA:
undetectable		 5axaC-3hdyA:
23.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AYF_A_C7HA402_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE
SETD7)		 3hdy UDP-GALACTOPYRANOSE
MUTASE
(Deinococcus
radiodurans) 		4 / 5 GLY A  65
TYR A 334
TYR A  82
GLY A  83
 None
FAD  A 450 ( 4.8A)
None
FAD  A 450 ( 4.1A)
 0.87A 5ayfA-3hdyA:
undetectable		 5ayfA-3hdyA:
19.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DGX_A_017A101_0
(PROTEASE)		 3hdy UDP-GALACTOPYRANOSE
MUTASE
(Deinococcus
radiodurans) 		5 / 12 GLY A  38
ALA A  37
VAL A 237
VAL A  55
ILE A  57
 FAD  A 450 (-3.3A)
None
None
None
None
 0.87A 6dgxA-3hdyA:
undetectable		 6dgxA-3hdyA:
10.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DH6_A_017A104_0
(PROTEASE)		 3hdy UDP-GALACTOPYRANOSE
MUTASE
(Deinococcus
radiodurans) 		5 / 12 GLY A  38
ALA A  37
VAL A 237
VAL A  55
ILE A  57
 FAD  A 450 (-3.3A)
None
None
None
None
 0.88A 6dh6A-3hdyA:
undetectable		 6dh6A-3hdyA:
10.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DIF_B_TPVB201_1
(HIV-1 PROTEASE)		 3hdy UDP-GALACTOPYRANOSE
MUTASE
(Deinococcus
radiodurans) 		5 / 12 GLY A  38
ALA A  37
VAL A 237
VAL A  55
ILE A  57
 FAD  A 450 (-3.3A)
None
None
None
None
 0.83A 6difB-3hdyA:
undetectable		 6difB-3hdyA:
10.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DIL_B_TPVB201_1
(HIV-1 PROTEASE)		 3hdy UDP-GALACTOPYRANOSE
MUTASE
(Deinococcus
radiodurans) 		5 / 12 GLY A  38
ALA A  37
VAL A 237
VAL A  55
ILE A  57
 FAD  A 450 (-3.3A)
None
None
None
None
 0.83A 6dilB-3hdyA:
undetectable		 6dilB-3hdyA:
11.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DIL_B_TPVB201_1
(HIV-1 PROTEASE)		 3hdy UDP-GALACTOPYRANOSE
MUTASE
(Deinococcus
radiodurans) 		5 / 12 LEU A 230
ALA A  49
ILE A 256
VAL A 237
ILE A 235
 None
 0.83A 6dilB-3hdyA:
undetectable		 6dilB-3hdyA:
11.94