SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3he1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J3J_A_CP6A609_1
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 3he1 MAJOR EXPORTED HCP3
PROTEIN
(Pseudomonas
aeruginosa) 		5 / 10 ILE A  17
ALA A  21
ASP A  75
ILE A  96
ILE A   9
 None
 1.21A 1j3jA-3he1A:
undetectable		 1j3jA-3he1A:
19.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MX1_F_THAF6_1
(LIVER
CARBOXYLESTERASE I)		 3he1 MAJOR EXPORTED HCP3
PROTEIN
(Pseudomonas
aeruginosa) 		6 / 12 GLY A  15
GLY A  11
VAL A  94
LEU A  91
LEU A  80
MET A   7
 None
 1.24A 1mx1F-3he1A:
undetectable		 1mx1F-3he1A:
15.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BL9_A_CP6A1240_1
(DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 3he1 MAJOR EXPORTED HCP3
PROTEIN
(Pseudomonas
aeruginosa) 		5 / 12 ILE A  17
ALA A  21
ASP A  75
ILE A  96
ILE A   9
 None
 1.14A 2bl9A-3he1A:
undetectable		 2bl9A-3he1A:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BLA_A_CP6A302_1
(DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 3he1 MAJOR EXPORTED HCP3
PROTEIN
(Pseudomonas
aeruginosa) 		5 / 11 ILE A  17
ALA A  21
ASP A  75
ILE A  96
ILE A   9
 None
 1.28A 2blaA-3he1A:
undetectable		 2blaA-3he1A:
22.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MBG_A_ACTA207_0
(FAD-LINKED
SULFHYDRYL OXIDASE
ALR)		 3he1 MAJOR EXPORTED HCP3
PROTEIN
(Pseudomonas
aeruginosa) 		4 / 7 LEU A  81
ASP A  75
THR A  18
ALA A  77
 None
 1.16A 3mbgA-3he1A:
undetectable
3mbgB-3he1A:
undetectable		 3mbgA-3he1A:
26.06
3mbgB-3he1A:
26.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5P_B_H4BB600_1
(NITRIC OXIDE
SYNTHASE)		 3he1 MAJOR EXPORTED HCP3
PROTEIN
(Pseudomonas
aeruginosa) 		4 / 6 TRP A  98
PHE A  44
GLU A  95
VAL A 114
 None
 1.47A 3n5pA-3he1A:
undetectable
3n5pB-3he1A:
undetectable		 3n5pA-3he1A:
18.33
3n5pB-3he1A:
18.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QGT_A_CP6A609_1
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 3he1 MAJOR EXPORTED HCP3
PROTEIN
(Pseudomonas
aeruginosa) 		5 / 10 ILE A  17
ALA A  21
ASP A  75
ILE A  96
ILE A   9
 None
 1.20A 3qgtA-3he1A:
undetectable		 3qgtA-3he1A:
14.66