SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3hei'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2O5Y_H_STRH249_1 (CHIMERIC ANTIBODY FAB 1E9-DB3)	3hei	EPHRIN TYPE-A RECEPTOR 2 EPHRIN-A1 (Homo sapiens)	4 / 7	ASN A 30 GLY B 117 THR B 115 SER A 41	None	1.16A	2o5yH-3heiA: 2.0 2o5yL-3heiA: undetectable	2o5yH-3heiA: 22.36 2o5yL-3heiA: 22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3LP1_A_NVPA701_1 (REVERSE TRANSCRIPTASE/RIBONU CLEASE H)	3hei	EPHRIN TYPE-A RECEPTOR 2 (Homo sapiens)	5 / 10	ASN A 52 VAL A 42 TYR A 40 GLY A 24 TRP A 16	None	1.49A	3lp1A-3heiA: undetectable	3lp1A-3heiA: 14.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5NWW_A_ACAA18_2 (SCRFP-TAG,GP41)	3hei	EPHRIN-A1 (Homo sapiens)	3 / 3	LYS B 103 TRP B 90 SER B 105	None	1.16A	5nwwA-3heiB: undetectable	5nwwA-3heiB: 14.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6FGD_A_ACTA812_0 (GEPHYRIN)	3hei	EPHRIN TYPE-A RECEPTOR 2 EPHRIN-A1 (Homo sapiens; Homo sapiens)	4 / 6	GLU B 119 ARG A 76 PHE A 81 PRO A 82	None	1.15A	6fgdA-3heiB: undetectable	6fgdA-3heiB: 13.02

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2O5Y_H_STRH249_1","CHIMERIC ANTIBODY FAB 1E9-DB3;CHIMERIC ANTIBODY FAB 1E9-DB3","3hei","EPHRIN TYPE-A RECEPTOR 2;EPHRIN-A1","Homo sapiens",4,"ASN A  30;GLY B 117;THR B 115;SER A  41","None","1.16A","2o5yH-3heiA:2.0;2o5yL-3heiA:undetectable","2o5yH-3heiA:22.36;2o5yL-3heiA:22.17"],["3LP1_A_NVPA701_1","REVERSE TRANSCRIPTASE\/RIBONUCLEASE H","3hei","EPHRIN TYPE-A RECEPTOR 2","Homo sapiens",5,"ASN A  52;VAL A  42;TYR A  40;GLY A  24;TRP A  16","None","1.49A","3lp1A-3heiA:undetectable","3lp1A-3heiA:14.67"],["5NWW_A_ACAA18_2","SCRFP-TAG,GP41","3hei","EPHRIN-A1","Homo sapiens",3,"LYS B 103;TRP B  90;SER B 105","None","1.16A","5nwwA-3heiB:undetectable","5nwwA-3heiB:14.47"],["6FGD_A_ACTA812_0","GEPHYRIN","3hei","EPHRIN TYPE-A RECEPTOR 2;EPHRIN-A1","Homo sapiens;Homo sapiens",4,"GLU B 119;ARG A  76;PHE A  81;PRO A  82","None","1.15A","6fgdA-3heiB:undetectable","6fgdA-3heiB:13.02"]]