SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3heo'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LH6_A_NIOA155_1
(LEGHEMOGLOBIN A
(NICOTINATE MET))		 3heo MYOGLOBIN
(Equus
caballus) 		5 / 7 PHE A  33
PHE A  43
PHE A  46
VAL A  68
HIS A  93
 None
HEM  A 154 ( 4.0A)
None
HEM  A 154 ( 3.8A)
HEM  A 154 (-3.2A)
 1.41A 1lh6A-3heoA:
16.3		 1lh6A-3heoA:
26.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MXG_A_ACRA442_1
(ALPHA AMYLASE)		 3heo MYOGLOBIN
(Equus
caballus) 		5 / 11 GLY A 124
GLU A   6
GLY A 129
GLN A 128
GLY A   5
 None
 0.91A 1mxgA-3heoA:
undetectable		 1mxgA-3heoA:
16.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3I5U_A_SAMA401_0
(O-METHYLTRANSFERASE)		 3heo MYOGLOBIN
(Equus
caballus) 		5 / 12 TRP A   7
LEU A  89
GLY A  74
GLY A  73
LEU A  11
 None
HEM  A 154 (-4.6A)
None
None
None
 1.09A 3i5uA-3heoA:
undetectable		 3i5uA-3heoA:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3I5U_B_SAMB401_0
(O-METHYLTRANSFERASE)		 3heo MYOGLOBIN
(Equus
caballus) 		5 / 12 TRP A   7
LEU A  89
GLY A  74
GLY A  73
LEU A  11
 None
HEM  A 154 (-4.6A)
None
None
None
 1.08A 3i5uB-3heoA:
undetectable		 3i5uB-3heoA:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MDB_A_RLTA401_1
(MARINER MOS1
TRANSPOSASE)		 3heo MYOGLOBIN
(Equus
caballus) 		4 / 6 ASP A 141
ASN A 140
ALA A 143
TYR A 146
 None
 1.17A 4mdbA-3heoA:
undetectable		 4mdbA-3heoA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XI3_C_29SC601_2
(ESTROGEN RECEPTOR)		 3heo MYOGLOBIN
(Equus
caballus) 		4 / 6 LEU A   2
ASP A   4
ILE A  75
HIS A  82
 None
 0.84A 4xi3C-3heoA:
undetectable		 4xi3C-3heoA:
20.16