SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3hfh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TEH_B_DAHB786_1
(PHENYLALANYL-TRNA
SYNTHETASE BETA
CHAIN)
3hfh TRANSCRIPTION
ELONGATION REGULATOR
1

(Homo
sapiens)
4 / 7 LEU A 671
GLU A 717
ALA A 677
PHE A 678
MLY  A 667 ( 4.4A)
MLY  A 721 ( 4.2A)
None
None
0.96A 3tehB-3hfhA:
undetectable
3tehB-3hfhA:
13.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VM4_A_IZPA1_1
(FATTY ACID
ALPHA-HYDROXYLASE)
3hfh TRANSCRIPTION
ELONGATION REGULATOR
1

(Homo
sapiens)
4 / 5 LEU A 802
ARG A 826
PRO A 825
ALA A 829
None
None
MLY  A 828 ( 4.4A)
MLY  A 828 ( 3.7A)
1.49A 3vm4A-3hfhA:
undetectable
3vm4A-3hfhA:
17.19