SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3hfi'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JQD_A_HSMA600_1
(HISTAMINE
N-METHYLTRANSFERASE)		 3hfi PUTATIVE REGULATOR
(Escherichia
coli) 		4 / 7 PHE A  92
GLN A 136
VAL A 151
ASN A  71
 None
 1.32A 1jqdA-3hfiA:
undetectable		 1jqdA-3hfiA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWV_A_BCZA513_1
(NEURAMINIDASE)		 3hfi PUTATIVE REGULATOR
(Escherichia
coli) 		3 / 3 ARG A 113
GLU A 135
ARG A 119
 None
 1.00A 4mwvA-3hfiA:
undetectable		 4mwvA-3hfiA:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_W_BEZW801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 3hfi PUTATIVE REGULATOR
(Escherichia
coli) 		4 / 5 ILE A  95
GLY A  80
ILE A  73
LEU A  98
 None
 0.86A 5dzkB-3hfiA:
undetectable
5dzkI-3hfiA:
undetectable
5dzkW-3hfiA:
undetectable		 5dzkB-3hfiA:
22.12
5dzkI-3hfiA:
24.42
5dzkW-3hfiA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_Y_BEZY801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 3hfi PUTATIVE REGULATOR
(Escherichia
coli) 		4 / 5 ILE A  95
GLY A  80
ILE A  73
LEU A  98
 None
 0.77A 5dzkd-3hfiA:
undetectable
5dzkk-3hfiA:
undetectable
5dzky-3hfiA:
undetectable		 5dzkd-3hfiA:
22.12
5dzkk-3hfiA:
24.42
5dzky-3hfiA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_Z_BEZZ801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
BEZ-LEU-LEU)		 3hfi PUTATIVE REGULATOR
(Escherichia
coli) 		4 / 4 ILE A  95
GLY A  80
ILE A  73
LEU A  98
 None
 0.87A 5dzkl-3hfiA:
undetectable
5dzkz-3hfiA:
undetectable		 5dzkl-3hfiA:
24.42
5dzkz-3hfiA:
18.18