SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3hfq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1D0V_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 3hfq UNCHARACTERIZED
PROTEIN LP_2219
(Lactobacillus
plantarum) 		4 / 8 GLY A  34
GLY A   8
PHE A   7
GLY A  17
 None
 0.71A 1d0vA-3hfqA:
undetectable		 1d0vA-3hfqA:
23.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JHA_A_NIOA991_1
(NICOTINATE
MONONUCLEOTIDE:5,6-D
IMETHYLBENZIMIDAZOLE
PHOSPHORIBOSYLTRANSF
ERASE)		 3hfq UNCHARACTERIZED
PROTEIN LP_2219
(Lactobacillus
plantarum) 		4 / 8 GLY A  34
GLY A   8
PHE A   7
GLY A  17
 None
 0.70A 1jhaA-3hfqA:
undetectable		 1jhaA-3hfqA:
23.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHU_A_ESTA301_1
(SEX HORMONE-BINDING
GLOBULIN)		 3hfq UNCHARACTERIZED
PROTEIN LP_2219
(Lactobacillus
plantarum) 		5 / 12 GLY A   8
ASP A 290
PHE A   7
ILE A  18
LEU A  53
 None
 1.24A 1lhuA-3hfqA:
undetectable		 1lhuA-3hfqA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FL5_F_RBFF204_1
(IMMUNOGLOBULIN IGG1
LAMBDA LIGHT CHAIN
IMMUNOGLOBULIN IGG1
HEAVY CHAIN)		 3hfq UNCHARACTERIZED
PROTEIN LP_2219
(Lactobacillus
plantarum) 		4 / 8 TYR A 236
ASN A 258
ARG A 259
VAL A 256
 None
None
PO4  A 402 (-2.5A)
None
 1.15A 2fl5E-3hfqA:
undetectable
2fl5F-3hfqA:
undetectable		 2fl5E-3hfqA:
21.57
2fl5F-3hfqA:
23.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PNC_B_CLUB809_1
(COPPER AMINE
OXIDASE, LIVER
ISOZYME)		 3hfq UNCHARACTERIZED
PROTEIN LP_2219
(Lactobacillus
plantarum) 		4 / 6 ALA A 244
ASP A 290
TYR A  44
HIS A 191
 None
 1.44A 2pncB-3hfqA:
1.9		 2pncB-3hfqA:
18.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q83_B_ADNB2_1
(YTAA PROTEIN)		 3hfq UNCHARACTERIZED
PROTEIN LP_2219
(Lactobacillus
plantarum) 		4 / 6 ILE A   5
PRO A  42
LEU A  53
ILE A  18
 None
 1.03A 2q83B-3hfqA:
undetectable		 2q83B-3hfqA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QO4_A_CHDA130_0
(LIVER-BASIC FATTY
ACID BINDING PROTEIN)		 3hfq UNCHARACTERIZED
PROTEIN LP_2219
(Lactobacillus
plantarum) 		5 / 12 LEU A 154
ALA A  92
VAL A  91
THR A 124
MET A 113
 None
 1.23A 2qo4A-3hfqA:
3.2		 2qo4A-3hfqA:
17.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LN1_D_CELD682_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3hfq UNCHARACTERIZED
PROTEIN LP_2219
(Lactobacillus
plantarum) 		4 / 5 LEU A 293
ARG A 338
ILE A   5
PHE A 339
 None
 1.12A 3ln1D-3hfqA:
undetectable		 3ln1D-3hfqA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NVC_A_SALA370_1
(GENTISATE
1,2-DIOXYGENASE)		 3hfq UNCHARACTERIZED
PROTEIN LP_2219
(Lactobacillus
plantarum) 		4 / 6 GLN A 305
HIS A 144
HIS A 191
ARG A 259
 None
PO4  A 402 (-3.8A)
None
PO4  A 402 (-2.5A)
 1.18A 3nvcA-3hfqA:
undetectable		 3nvcA-3hfqA:
23.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8H_A_RKEA401_1
(PROTON-GATED ION
CHANNEL)		 3hfq UNCHARACTERIZED
PROTEIN LP_2219
(Lactobacillus
plantarum) 		4 / 8 TYR A 145
VAL A 166
PHE A 194
LEU A 192
 None
 0.94A 4f8hA-3hfqA:
undetectable
4f8hB-3hfqA:
undetectable		 4f8hA-3hfqA:
22.31
4f8hB-3hfqA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8H_B_RKEB401_1
(PROTON-GATED ION
CHANNEL)		 3hfq UNCHARACTERIZED
PROTEIN LP_2219
(Lactobacillus
plantarum) 		4 / 8 TYR A 145
VAL A 166
PHE A 194
LEU A 192
 None
 0.97A 4f8hB-3hfqA:
undetectable
4f8hC-3hfqA:
undetectable		 4f8hB-3hfqA:
22.31
4f8hC-3hfqA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8H_C_RKEC401_1
(PROTON-GATED ION
CHANNEL)		 3hfq UNCHARACTERIZED
PROTEIN LP_2219
(Lactobacillus
plantarum) 		4 / 8 TYR A 145
VAL A 166
PHE A 194
LEU A 192
 None
 0.95A 4f8hC-3hfqA:
undetectable
4f8hD-3hfqA:
undetectable		 4f8hC-3hfqA:
22.31
4f8hD-3hfqA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8H_D_RKED401_1
(PROTON-GATED ION
CHANNEL)		 3hfq UNCHARACTERIZED
PROTEIN LP_2219
(Lactobacillus
plantarum) 		4 / 8 TYR A 145
VAL A 166
PHE A 194
LEU A 192
 None
 0.94A 4f8hD-3hfqA:
undetectable
4f8hE-3hfqA:
undetectable		 4f8hD-3hfqA:
22.31
4f8hE-3hfqA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F8H_E_RKEE401_1
(PROTON-GATED ION
CHANNEL)		 3hfq UNCHARACTERIZED
PROTEIN LP_2219
(Lactobacillus
plantarum) 		4 / 8 VAL A 166
PHE A 194
LEU A 192
TYR A 145
 None
 0.95A 4f8hA-3hfqA:
undetectable
4f8hE-3hfqA:
undetectable		 4f8hA-3hfqA:
22.31
4f8hE-3hfqA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KOV_A_KOVA204_1
(UNCHARACTERIZED
PROTEIN)		 3hfq UNCHARACTERIZED
PROTEIN LP_2219
(Lactobacillus
plantarum) 		5 / 12 TYR A 236
PRO A 233
ASN A 240
ILE A 211
LEU A 277
 None
 1.48A 4kovA-3hfqA:
undetectable		 4kovA-3hfqA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XRG_A_AG2A502_1
(HOMOSPERMIDINE
SYNTHASE)		 3hfq UNCHARACTERIZED
PROTEIN LP_2219
(Lactobacillus
plantarum) 		5 / 12 GLU A  95
VAL A  93
SER A  48
TYR A  54
LEU A  78
 None
 1.47A 4xrgA-3hfqA:
0.0		 4xrgA-3hfqA:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XRG_A_AG2A502_1
(HOMOSPERMIDINE
SYNTHASE)		 3hfq UNCHARACTERIZED
PROTEIN LP_2219
(Lactobacillus
plantarum) 		5 / 12 GLU A  95
VAL A  93
TYR A  54
ASP A 118
LEU A  78
 None
 1.33A 4xrgA-3hfqA:
0.0		 4xrgA-3hfqA:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YO9_A_ACTA403_0
(3C-LIKE PROTEINASE)		 3hfq UNCHARACTERIZED
PROTEIN LP_2219
(Lactobacillus
plantarum) 		4 / 5 TYR A 101
SER A 170
LEU A  99
GLN A 174
 None
 1.11A 4yo9A-3hfqA:
0.0
4yo9B-3hfqA:
0.0		 4yo9A-3hfqA:
22.44
4yo9B-3hfqA:
22.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H5F_A_SAMA301_1
(PROTEIN ARGININE
N-METHYLTRANSFERASE
SFM1)		 3hfq UNCHARACTERIZED
PROTEIN LP_2219
(Lactobacillus
plantarum) 		4 / 5 GLY A  17
PRO A  87
THR A  39
THR A   9
 None
 1.26A 5h5fA-3hfqA:
undetectable		 5h5fA-3hfqA:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JW1_B_CELB602_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3hfq UNCHARACTERIZED
PROTEIN LP_2219
(Lactobacillus
plantarum) 		4 / 6 VAL A 302
ARG A 338
ILE A   5
PHE A 339
 None
 0.93A 5jw1B-3hfqA:
undetectable		 5jw1B-3hfqA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KIR_A_RCXA601_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3hfq UNCHARACTERIZED
PROTEIN LP_2219
(Lactobacillus
plantarum) 		3 / 3 ARG A 338
ILE A   5
PHE A 339
 None
 0.68A 5kirA-3hfqA:
undetectable		 5kirA-3hfqA:
20.11