SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3hg7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H9Z_A_RWFA3001_1
(SERUM ALBUMIN)		 3hg7 D-ISOMER SPECIFIC
2-HYDROXYACID
DEHYDROGENASE FAMILY
PROTEIN
(Aeromonas
salmonicida) 		5 / 11 ALA A  65
LEU A  68
LEU A  62
LEU A  81
ALA A  53
 None
 1.15A 1h9zA-3hg7A:
undetectable		 1h9zA-3hg7A:
18.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_B_SAMB300_0
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 3hg7 D-ISOMER SPECIFIC
2-HYDROXYACID
DEHYDROGENASE FAMILY
PROTEIN
(Aeromonas
salmonicida) 		5 / 12 GLY A 137
GLY A 159
GLY A 163
GLY A 140
HIS A 154
 None
 0.83A 2oxtB-3hg7A:
5.3		 2oxtB-3hg7A:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CJT_O_SAMO302_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 3hg7 D-ISOMER SPECIFIC
2-HYDROXYACID
DEHYDROGENASE FAMILY
PROTEIN
(Aeromonas
salmonicida) 		5 / 12 LEU A 146
GLY A 147
GLY A 149
SER A 150
LEU A 202
 None
 0.83A 3cjtO-3hg7A:
7.9		 3cjtO-3hg7A:
23.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QXV_D_MTXD2000_2
(ANTI-METHOTREXATE
CDR1-4 GRAFT VHH)		 3hg7 D-ISOMER SPECIFIC
2-HYDROXYACID
DEHYDROGENASE FAMILY
PROTEIN
(Aeromonas
salmonicida) 		3 / 3 LEU A 262
ARG A 245
ASN A 236
 None
 0.66A 3qxvD-3hg7A:
undetectable		 3qxvD-3hg7A:
16.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_A_ADNA401_2
(ADENOSINE KINASE)		 3hg7 D-ISOMER SPECIFIC
2-HYDROXYACID
DEHYDROGENASE FAMILY
PROTEIN
(Aeromonas
salmonicida) 		4 / 4 LEU A  10
SER A  12
LEU A  51
LEU A  22
 None
 1.07A 4n09A-3hg7A:
undetectable		 4n09A-3hg7A:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OV9_A_CVIA608_0
(ACETYLCHOLINESTERASE)		 3hg7 D-ISOMER SPECIFIC
2-HYDROXYACID
DEHYDROGENASE FAMILY
PROTEIN
(Aeromonas
salmonicida) 		4 / 7 THR A   7
LEU A   8
VAL A 294
TYR A 297
 None
 0.84A 5ov9A-3hg7A:
undetectable		 5ov9A-3hg7A:
20.83