SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3hhc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXE_A_1FLA2003_1
(SERUM ALBUMIN)		 3hhc INTERLEUKIN-28B
(Homo
sapiens) 		5 / 9 LEU A 100
ARG A 101
LEU A  61
LEU A 148
ALA A  66
 None
 1.27A 2bxeA-3hhcA:
undetectable		 2bxeA-3hhcA:
15.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OUZ_A_C3DA999_0
(ESTROGEN RECEPTOR)		 3hhc INTERLEUKIN-28B
(Homo
sapiens) 		5 / 12 LEU A  69
LEU A 125
LEU A  61
ILE A  96
LEU A 148
 None
 1.06A 2ouzA-3hhcA:
undetectable		 2ouzA-3hhcA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q72_A_IXXA801_1
(TRANSPORTER)		 3hhc INTERLEUKIN-28B
(Homo
sapiens) 		5 / 11 LEU A  72
LEU A  86
GLN A  88
ALA A  19
LEU A 149
 None
None
None
IOD  A 164 ( 4.0A)
None
 1.18A 2q72A-3hhcA:
2.8		 2q72A-3hhcA:
16.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HCR_A_CHDA4_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3hhc INTERLEUKIN-28B
(Homo
sapiens) 		3 / 3 LEU A  90
PRO A  89
LEU A  93
 None
IOD  A 164 ( 4.4A)
None
 0.53A 3hcrA-3hhcA:
undetectable		 3hcrA-3hhcA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JB2_A_SAMA1101_1
(STRUCTURAL PROTEIN
VP3)		 3hhc INTERLEUKIN-28B
(Homo
sapiens) 		3 / 3 GLU A  73
ASP A  77
ASP A  87
 None
 0.75A 3jb2A-3hhcA:
undetectable		 3jb2A-3hhcA:
11.11