SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3hhj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3CR4_X_PNTX101_0 (PROTEIN S100-B)	3hhj	MUTATOR MUTT PROTEIN (Bartonella henselae)	3 / 3	CYH A 114 HIS A 116 PHE A 93	None	0.88A	3cr4X-3hhjA: undetectable	3cr4X-3hhjA: 20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3DZG_B_NCAB302_0 (ADP-RIBOSYL CYCLASE 1)	3hhj	MUTATOR MUTT PROTEIN (Bartonella henselae)	4 / 7	LEU A 36 ASP A 38 TRP A 131 THR A 46	None	1.35A	3dzgB-3hhjA: undetectable	3dzgB-3hhjA: 22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4G1Q_A_T27A601_1 (REVERSE TRANSCRIPTASE/RIBONU CLEASE H)	3hhj	MUTATOR MUTT PROTEIN (Bartonella henselae)	5 / 12	PRO A 61 LEU A 75 VAL A 87 PHE A 113 PRO A 94	None	1.47A	4g1qA-3hhjA: undetectable	4g1qA-3hhjA: 14.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4IFV_A_T27A601_1 (EXORIBONUCLEASE H, P66 RT)	3hhj	MUTATOR MUTT PROTEIN (Bartonella henselae)	5 / 12	PRO A 61 LEU A 75 VAL A 87 PHE A 113 PRO A 94	None	1.48A	4ifvA-3hhjA: undetectable	4ifvA-3hhjA: 14.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4IFY_A_T27A601_1 (REVERSE TRANSCRIPTASE/RIBONU CLEASE H)	3hhj	MUTATOR MUTT PROTEIN (Bartonella henselae)	5 / 12	PRO A 61 LEU A 75 VAL A 87 PHE A 113 PRO A 94	None	1.49A	4ifyA-3hhjA: undetectable	4ifyA-3hhjA: 14.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4IG3_A_T27A601_1 (REVERSE TRANSCRIPTASE/RIBONU CLEASE H)	3hhj	MUTATOR MUTT PROTEIN (Bartonella henselae)	5 / 12	PRO A 61 LEU A 75 VAL A 87 PHE A 113 PRO A 94	None	1.50A	4ig3A-3hhjA: undetectable	4ig3A-3hhjA: 14.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4KFB_A_T27A607_1 (REVERSE TRANSCRIPTASE/RIBONU CLEASE H, EXORIBONUCLEA P66 RT)	3hhj	MUTATOR MUTT PROTEIN (Bartonella henselae)	5 / 12	PRO A 61 LEU A 75 VAL A 87 PHE A 113 PRO A 94	None	1.49A	4kfbA-3hhjA: undetectable	4kfbA-3hhjA: 14.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5X6Y_A_SAMA902_1 (MRNA CAPPING ENZYME P5)	3hhj	MUTATOR MUTT PROTEIN (Bartonella henselae)	3 / 3	TYR A 140 ASP A 138 ASP A 136	None	0.82A	5x6yA-3hhjA: undetectable	5x6yA-3hhjA: 10.99

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3CR4_X_PNTX101_0","PROTEIN S100-B","3hhj","MUTATOR MUTT PROTEIN","Bartonella henselae",3,"CYH A 114;HIS A 116;PHE A  93","None","0.88A","3cr4X-3hhjA:undetectable","3cr4X-3hhjA:20.25"],["3DZG_B_NCAB302_0","ADP-RIBOSYL CYCLASE 1","3hhj","MUTATOR MUTT PROTEIN","Bartonella henselae",4,"LEU A  36;ASP A  38;TRP A 131;THR A  46","None","1.35A","3dzgB-3hhjA:undetectable","3dzgB-3hhjA:22.71"],["4G1Q_A_T27A601_1","REVERSE TRANSCRIPTASE\/RIBONUCLEASE H","3hhj","MUTATOR MUTT PROTEIN","Bartonella henselae",5,"PRO A  61;LEU A  75;VAL A  87;PHE A 113;PRO A  94","None","1.47A","4g1qA-3hhjA:undetectable","4g1qA-3hhjA:14.57"],["4IFV_A_T27A601_1","EXORIBONUCLEASE H, P66 RT","3hhj","MUTATOR MUTT PROTEIN","Bartonella henselae",5,"PRO A  61;LEU A  75;VAL A  87;PHE A 113;PRO A  94","None","1.48A","4ifvA-3hhjA:undetectable","4ifvA-3hhjA:14.57"],["4IFY_A_T27A601_1","REVERSE TRANSCRIPTASE\/RIBONUCLEASE H","3hhj","MUTATOR MUTT PROTEIN","Bartonella henselae",5,"PRO A  61;LEU A  75;VAL A  87;PHE A 113;PRO A  94","None","1.49A","4ifyA-3hhjA:undetectable","4ifyA-3hhjA:14.57"],["4IG3_A_T27A601_1","REVERSE TRANSCRIPTASE\/RIBONUCLEASE H","3hhj","MUTATOR MUTT PROTEIN","Bartonella henselae",5,"PRO A  61;LEU A  75;VAL A  87;PHE A 113;PRO A  94","None","1.50A","4ig3A-3hhjA:undetectable","4ig3A-3hhjA:14.57"],["4KFB_A_T27A607_1","REVERSE TRANSCRIPTASE\/RIBONUCLEASE H, EXORIBONUCLEA P66 RT","3hhj","MUTATOR MUTT PROTEIN","Bartonella henselae",5,"PRO A  61;LEU A  75;VAL A  87;PHE A 113;PRO A  94","None","1.49A","4kfbA-3hhjA:undetectable","4kfbA-3hhjA:14.57"],["5X6Y_A_SAMA902_1","MRNA CAPPING ENZYME P5","3hhj","MUTATOR MUTT PROTEIN","Bartonella henselae",3,"TYR A 140;ASP A 138;ASP A 136","None","0.82A","5x6yA-3hhjA:undetectable","5x6yA-3hhjA:10.99"]]