SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3hi2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KT5_A_RTLA176_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 3hi2 HTH-TYPE
TRANSCRIPTIONAL
REGULATOR MQSA(YGIT)
MOTILITY
QUORUM-SENSING
REGULATOR MQSR
(Escherichia
coli;
Escherichia
coli) 		5 / 12 LEU B  37
ALA A  59
ALA A  55
MET A  54
LEU B  29
 None
 1.31A 1kt5A-3hi2B:
undetectable		 1kt5A-3hi2B:
21.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DH0_A_017A101_1
(PROTEASE)		 3hi2 MOTILITY
QUORUM-SENSING
REGULATOR MQSR
(Escherichia
coli) 		5 / 12 GLY B  20
ASP B  89
VAL B  86
ILE B  47
VAL B  93
 None
 0.92A 6dh0B-3hi2B:
undetectable		 6dh0B-3hi2B:
23.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FGD_A_ACTA821_0
(GEPHYRIN)		 3hi2 HTH-TYPE
TRANSCRIPTIONAL
REGULATOR MQSA(YGIT)
(Escherichia
coli) 		3 / 3 ARG A  25
PHE A  22
GLY A  24
 None
GOL  A3968 (-4.7A)
None
 0.74A 6fgdA-3hi2A:
undetectable		 6fgdA-3hi2A:
11.46