SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3hi8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK1_A_T44A3004_1
(SERUM ALBUMIN)		 3hi8 PROLIFERATING CELL
NUCLEAR ANTIGEN PCNA
(Haloferax
volcanii) 		4 / 6 PHE A   2
GLU A  92
LEU A  97
VAL A  68
 None
 0.90A 1hk1A-3hi8A:
undetectable		 1hk1A-3hi8A:
15.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HK2_A_T44A3004_1
(SERUM ALBUMIN)		 3hi8 PROLIFERATING CELL
NUCLEAR ANTIGEN PCNA
(Haloferax
volcanii) 		4 / 7 PHE A   2
GLU A  92
LEU A  97
VAL A  68
 None
 0.81A 1hk2A-3hi8A:
undetectable		 1hk2A-3hi8A:
15.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P7R_A_NCTA440_1
(CYTOCHROME P450-CAM)		 3hi8 PROLIFERATING CELL
NUCLEAR ANTIGEN PCNA
(Haloferax
volcanii) 		4 / 7 PHE A 163
VAL A 223
VAL A 213
ILE A 131
 None
 0.90A 1p7rA-3hi8A:
undetectable		 1p7rA-3hi8A:
21.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TDR_B_MTXB170_1
(TELLUROMETHIONYL
DIHYDROFOLATE
REDUCTASE)		 3hi8 PROLIFERATING CELL
NUCLEAR ANTIGEN PCNA
(Haloferax
volcanii) 		5 / 10 ALA A  14
LEU A  34
ILE A  66
LEU A  90
THR A  10
 None
 1.29A 1tdrB-3hi8A:
undetectable		 1tdrB-3hi8A:
24.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_J_CHDJ3060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 3hi8 PROLIFERATING CELL
NUCLEAR ANTIGEN PCNA
(Haloferax
volcanii) 		4 / 6 LEU A  15
ARG A  37
THR A  50
LEU A  51
 None
 0.85A 1v54A-3hi8A:
undetectable
1v54J-3hi8A:
undetectable		 1v54A-3hi8A:
20.53
1v54J-3hi8A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_W_CHDW4060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 3hi8 PROLIFERATING CELL
NUCLEAR ANTIGEN PCNA
(Haloferax
volcanii) 		4 / 7 LEU A  15
ARG A  37
THR A  50
LEU A  51
 None
 0.83A 1v54N-3hi8A:
undetectable
1v54W-3hi8A:
undetectable		 1v54N-3hi8A:
20.53
1v54W-3hi8A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_J_CHDJ3060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 3hi8 PROLIFERATING CELL
NUCLEAR ANTIGEN PCNA
(Haloferax
volcanii) 		4 / 7 LEU A  15
ARG A  37
THR A  50
LEU A  51
 None
 0.84A 1v55A-3hi8A:
undetectable
1v55J-3hi8A:
undetectable		 1v55A-3hi8A:
20.53
1v55J-3hi8A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_W_CHDW4060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 3hi8 PROLIFERATING CELL
NUCLEAR ANTIGEN PCNA
(Haloferax
volcanii) 		4 / 8 LEU A  15
ARG A  37
THR A  50
LEU A  51
 None
 0.86A 1v55N-3hi8A:
undetectable
1v55W-3hi8A:
undetectable		 1v55N-3hi8A:
20.53
1v55W-3hi8A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3hi8 PROLIFERATING CELL
NUCLEAR ANTIGEN PCNA
(Haloferax
volcanii) 		4 / 6 LEU A  15
ARG A  37
THR A  50
LEU A  51
 None
 0.85A 2dyrA-3hi8A:
undetectable
2dyrJ-3hi8A:
undetectable		 2dyrA-3hi8A:
20.53
2dyrJ-3hi8A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3hi8 PROLIFERATING CELL
NUCLEAR ANTIGEN PCNA
(Haloferax
volcanii) 		4 / 7 LEU A  15
ARG A  37
THR A  50
LEU A  51
 None
 0.81A 2dyrN-3hi8A:
undetectable
2dyrW-3hi8A:
undetectable		 2dyrN-3hi8A:
20.53
2dyrW-3hi8A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_J_CHDJ101_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3hi8 PROLIFERATING CELL
NUCLEAR ANTIGEN PCNA
(Haloferax
volcanii) 		4 / 6 LEU A  15
ARG A  37
THR A  50
LEU A  51
 None
 0.81A 2dysA-3hi8A:
undetectable
2dysJ-3hi8A:
undetectable		 2dysA-3hi8A:
20.53
2dysJ-3hi8A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_W_CHDW101_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3hi8 PROLIFERATING CELL
NUCLEAR ANTIGEN PCNA
(Haloferax
volcanii) 		4 / 6 LEU A  15
ARG A  37
THR A  50
LEU A  51
 None
 0.84A 2dysN-3hi8A:
undetectable
2dysW-3hi8A:
undetectable		 2dysN-3hi8A:
20.53
2dysW-3hi8A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3hi8 PROLIFERATING CELL
NUCLEAR ANTIGEN PCNA
(Haloferax
volcanii) 		4 / 6 LEU A  15
ARG A  37
THR A  50
LEU A  51
 None
 0.88A 2eijA-3hi8A:
undetectable
2eijJ-3hi8A:
undetectable		 2eijA-3hi8A:
20.53
2eijJ-3hi8A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3hi8 PROLIFERATING CELL
NUCLEAR ANTIGEN PCNA
(Haloferax
volcanii) 		4 / 8 LEU A  15
ARG A  37
THR A  50
LEU A  51
 None
 0.88A 2eijN-3hi8A:
undetectable
2eijW-3hi8A:
undetectable		 2eijN-3hi8A:
20.53
2eijW-3hi8A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3hi8 PROLIFERATING CELL
NUCLEAR ANTIGEN PCNA
(Haloferax
volcanii) 		4 / 7 LEU A  15
ARG A  37
THR A  50
LEU A  51
 None
 0.87A 2eikA-3hi8A:
undetectable
2eikJ-3hi8A:
undetectable		 2eikA-3hi8A:
20.53
2eikJ-3hi8A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3hi8 PROLIFERATING CELL
NUCLEAR ANTIGEN PCNA
(Haloferax
volcanii) 		4 / 8 LEU A  15
ARG A  37
THR A  50
LEU A  51
 None
 0.88A 2eikN-3hi8A:
undetectable
2eikW-3hi8A:
undetectable		 2eikN-3hi8A:
20.53
2eikW-3hi8A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3hi8 PROLIFERATING CELL
NUCLEAR ANTIGEN PCNA
(Haloferax
volcanii) 		4 / 6 LEU A  15
ARG A  37
THR A  50
LEU A  51
 None
 0.82A 2eilA-3hi8A:
undetectable
2eilJ-3hi8A:
undetectable		 2eilA-3hi8A:
20.53
2eilJ-3hi8A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3hi8 PROLIFERATING CELL
NUCLEAR ANTIGEN PCNA
(Haloferax
volcanii) 		4 / 8 LEU A  15
ARG A  37
THR A  50
LEU A  51
 None
 0.88A 2eilN-3hi8A:
undetectable
2eilW-3hi8A:
undetectable		 2eilN-3hi8A:
20.53
2eilW-3hi8A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3hi8 PROLIFERATING CELL
NUCLEAR ANTIGEN PCNA
(Haloferax
volcanii) 		4 / 8 LEU A  15
ARG A  37
THR A  50
LEU A  51
 None
 0.80A 2einA-3hi8A:
undetectable
2einJ-3hi8A:
undetectable		 2einA-3hi8A:
20.53
2einJ-3hi8A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EJT_A_SAMA501_0
(N(2),N(2)-DIMETHYLGU
ANOSINE TRNA
METHYLTRANSFERASE)		 3hi8 PROLIFERATING CELL
NUCLEAR ANTIGEN PCNA
(Haloferax
volcanii) 		5 / 12 LEU A  11
ALA A  82
ILE A 101
ALA A  77
ASP A  13
 None
 1.07A 2ejtA-3hi8A:
undetectable		 2ejtA-3hi8A:
24.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_C_SAMC300_1
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 3hi8 PROLIFERATING CELL
NUCLEAR ANTIGEN PCNA
(Haloferax
volcanii) 		4 / 4 SER A 149
GLY A 169
HIS A 164
ASP A 157
 None
 1.36A 2oxtC-3hi8A:
undetectable		 2oxtC-3hi8A:
23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZ7_A_CA4A1_2
(ANDROGEN RECEPTOR)		 3hi8 PROLIFERATING CELL
NUCLEAR ANTIGEN PCNA
(Haloferax
volcanii) 		4 / 6 LEU A 217
MET A  46
MET A 203
LEU A 240
 None
 1.28A 2oz7A-3hi8A:
undetectable		 2oz7A-3hi8A:
22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHF_A_ACTA508_0
(CHORISMATE SYNTHASE)		 3hi8 PROLIFERATING CELL
NUCLEAR ANTIGEN PCNA
(Haloferax
volcanii) 		4 / 5 LEU A 104
ARG A 100
ASP A 102
ILE A  99
 None
 1.11A 2qhfA-3hi8A:
undetectable		 2qhfA-3hi8A:
23.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3hi8 PROLIFERATING CELL
NUCLEAR ANTIGEN PCNA
(Haloferax
volcanii) 		4 / 6 LEU A  15
ARG A  37
THR A  50
LEU A  51
 None
 0.77A 2zxwA-3hi8A:
undetectable
2zxwJ-3hi8A:
undetectable		 2zxwA-3hi8A:
20.53
2zxwJ-3hi8A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZZA_A_FOLA164_0
(DIHYDROFOLATE
REDUCTASE)		 3hi8 PROLIFERATING CELL
NUCLEAR ANTIGEN PCNA
(Haloferax
volcanii) 		5 / 12 ALA A  14
LEU A  34
ILE A  66
LEU A  90
THR A  10
 None
 1.30A 2zzaA-3hi8A:
undetectable		 2zzaA-3hi8A:
26.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZZA_B_FOLB164_0
(DIHYDROFOLATE
REDUCTASE)		 3hi8 PROLIFERATING CELL
NUCLEAR ANTIGEN PCNA
(Haloferax
volcanii) 		5 / 11 ALA A  14
LEU A  34
ILE A  66
LEU A  90
THR A  10
 None
 1.30A 2zzaB-3hi8A:
undetectable		 2zzaB-3hi8A:
26.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3hi8 PROLIFERATING CELL
NUCLEAR ANTIGEN PCNA
(Haloferax
volcanii) 		4 / 8 LEU A  15
ARG A  37
THR A  50
LEU A  51
 None
 0.93A 3abkA-3hi8A:
undetectable
3abkJ-3hi8A:
undetectable		 3abkA-3hi8A:
20.53
3abkJ-3hi8A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3hi8 PROLIFERATING CELL
NUCLEAR ANTIGEN PCNA
(Haloferax
volcanii) 		4 / 7 LEU A  15
ARG A  37
THR A  50
LEU A  51
 None
 0.83A 3ablA-3hi8A:
undetectable
3ablJ-3hi8A:
undetectable		 3ablA-3hi8A:
20.53
3ablJ-3hi8A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3hi8 PROLIFERATING CELL
NUCLEAR ANTIGEN PCNA
(Haloferax
volcanii) 		4 / 8 LEU A  15
ARG A  37
THR A  50
LEU A  51
 None
 0.93A 3ablN-3hi8A:
undetectable
3ablW-3hi8A:
undetectable		 3ablN-3hi8A:
20.53
3ablW-3hi8A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3hi8 PROLIFERATING CELL
NUCLEAR ANTIGEN PCNA
(Haloferax
volcanii) 		4 / 6 LEU A  15
ARG A  37
THR A  50
LEU A  51
 None
 0.86A 3abmA-3hi8A:
undetectable
3abmJ-3hi8A:
undetectable		 3abmA-3hi8A:
20.53
3abmJ-3hi8A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3hi8 PROLIFERATING CELL
NUCLEAR ANTIGEN PCNA
(Haloferax
volcanii) 		4 / 8 LEU A  15
ARG A  37
THR A  50
LEU A  51
 None
 0.87A 3abmN-3hi8A:
undetectable
3abmW-3hi8A:
undetectable		 3abmN-3hi8A:
20.53
3abmW-3hi8A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3hi8 PROLIFERATING CELL
NUCLEAR ANTIGEN PCNA
(Haloferax
volcanii) 		4 / 7 LEU A  15
ARG A  37
THR A  50
LEU A  51
 None
 0.89A 3ag3A-3hi8A:
undetectable
3ag3J-3hi8A:
undetectable		 3ag3A-3hi8A:
20.53
3ag3J-3hi8A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 3hi8 PROLIFERATING CELL
NUCLEAR ANTIGEN PCNA
(Haloferax
volcanii) 		4 / 8 LEU A  15
ARG A  37
THR A  50
LEU A  51
 None
 0.76A 3ag3N-3hi8A:
undetectable
3ag3W-3hi8A:
undetectable		 3ag3N-3hi8A:
20.53
3ag3W-3hi8A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_J_CHDJ60_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 3hi8 PROLIFERATING CELL
NUCLEAR ANTIGEN PCNA
(Haloferax
volcanii) 		4 / 6 LEU A  15
ARG A  37
THR A  50
LEU A  51
 None
 0.83A 3asnA-3hi8A:
undetectable
3asnJ-3hi8A:
undetectable		 3asnA-3hi8A:
20.53
3asnJ-3hi8A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_W_CHDW1059_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 3hi8 PROLIFERATING CELL
NUCLEAR ANTIGEN PCNA
(Haloferax
volcanii) 		4 / 8 LEU A  15
ARG A  37
THR A  50
LEU A  51
 None
 0.88A 3asnN-3hi8A:
undetectable
3asnW-3hi8A:
undetectable		 3asnN-3hi8A:
20.53
3asnW-3hi8A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_J_CHDJ60_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 3hi8 PROLIFERATING CELL
NUCLEAR ANTIGEN PCNA
(Haloferax
volcanii) 		4 / 6 LEU A  15
ARG A  37
THR A  50
LEU A  51
 None
 0.83A 3asoA-3hi8A:
undetectable
3asoJ-3hi8A:
undetectable		 3asoA-3hi8A:
20.53
3asoJ-3hi8A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_W_CHDW1059_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 3hi8 PROLIFERATING CELL
NUCLEAR ANTIGEN PCNA
(Haloferax
volcanii) 		4 / 8 LEU A  15
ARG A  37
THR A  50
LEU A  51
 None
 0.86A 3asoN-3hi8A:
undetectable
3asoW-3hi8A:
undetectable		 3asoN-3hi8A:
20.53
3asoW-3hi8A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AXT_A_SAMA397_0
(PROBABLE
N(2),N(2)-DIMETHYLGU
ANOSINE TRNA
METHYLTRANSFERASE
TRM1)		 3hi8 PROLIFERATING CELL
NUCLEAR ANTIGEN PCNA
(Haloferax
volcanii) 		5 / 12 LEU A  11
ALA A  82
ILE A 101
ALA A  77
ASP A  13
 None
 1.09A 3axtA-3hi8A:
undetectable		 3axtA-3hi8A:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KLR_A_CHDA504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3hi8 PROLIFERATING CELL
NUCLEAR ANTIGEN PCNA
(Haloferax
volcanii) 		4 / 7 ARG A 117
PRO A 242
VAL A  44
MET A 239
 None
 1.25A 4klrA-3hi8A:
undetectable		 4klrA-3hi8A:
22.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZOW_A_CLMA500_0
(MULTIDRUG
TRANSPORTER MDFA)		 3hi8 PROLIFERATING CELL
NUCLEAR ANTIGEN PCNA
(Haloferax
volcanii) 		5 / 11 LEU A  15
LEU A  97
LEU A  90
ILE A  66
LEU A  73
 None
 1.00A 4zowA-3hi8A:
undetectable		 4zowA-3hi8A:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3hi8 PROLIFERATING CELL
NUCLEAR ANTIGEN PCNA
(Haloferax
volcanii) 		4 / 7 LEU A  15
ARG A  37
THR A  50
LEU A  51
 None
 0.82A 5iy5A-3hi8A:
undetectable
5iy5J-3hi8A:
undetectable		 5iy5A-3hi8A:
20.53
5iy5J-3hi8A:
20.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5J6H_A_NCAA402_0
(H-2 CLASS I
HISTOCOMPATIBILITY
ANTIGEN, Q10 ALPHA
CHAIN)		 3hi8 PROLIFERATING CELL
NUCLEAR ANTIGEN PCNA
(Haloferax
volcanii) 		3 / 3 PRO A 242
ARG A 243
GLU A 220
 None
 0.88A 5j6hA-3hi8A:
undetectable		 5j6hA-3hi8A:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3hi8 PROLIFERATING CELL
NUCLEAR ANTIGEN PCNA
(Haloferax
volcanii) 		4 / 6 LEU A  15
ARG A  37
THR A  50
LEU A  51
 None
 1.02A 5x1fA-3hi8A:
undetectable
5x1fJ-3hi8A:
undetectable		 5x1fA-3hi8A:
20.53
5x1fJ-3hi8A:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CB4_A_BEZA501_0
(CANAVALIN)		 3hi8 PROLIFERATING CELL
NUCLEAR ANTIGEN PCNA
(Haloferax
volcanii) 		4 / 8 ASN A 204
LEU A 200
VAL A 213
LEU A 225
 None
 0.88A 6cb4A-3hi8A:
undetectable		 6cb4A-3hi8A:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FDY_U_DB8U302_1
(-)		 3hi8 PROLIFERATING CELL
NUCLEAR ANTIGEN PCNA
(Haloferax
volcanii) 		5 / 9 LEU A  73
VAL A  68
SER A  35
LEU A  29
ILE A  66
 None
 1.41A 6fdyU-3hi8A:
undetectable		 6fdyU-3hi8A:
22.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 3hi8 PROLIFERATING CELL
NUCLEAR ANTIGEN PCNA
(Haloferax
volcanii) 		4 / 7 LEU A  15
ARG A  37
THR A  50
LEU A  51
 None
 0.92A 6nmfA-3hi8A:
undetectable
6nmfJ-3hi8A:
undetectable		 6nmfA-3hi8A:
20.53
6nmfJ-3hi8A:
20.59