SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3hij'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SQF_A_SAMA430_0
(SUN PROTEIN)		 3hij DIHYDRODIPICOLINATE
SYNTHASE
(Bacillus
anthracis) 		5 / 12 ALA A  10
GLY A  45
GLY A  44
ILE A   7
GLY A   5
 KPI  A 163 ( 3.2A)
KPI  A 163 ( 3.4A)
None
None
None
 0.97A 1sqfA-3hijA:
undetectable		 1sqfA-3hijA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FK8_A_SAMA302_1
(METHOXY MYCOLIC ACID
SYNTHASE 4)		 3hij DIHYDRODIPICOLINATE
SYNTHASE
(Bacillus
anthracis) 		3 / 3 SER A 141
THR A 149
GLN A 114
 None
 0.78A 2fk8A-3hijA:
undetectable		 2fk8A-3hijA:
22.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DL9_B_V2HB602_0
(CYTOCHROME P450 2R1)		 3hij DIHYDRODIPICOLINATE
SYNTHASE
(Bacillus
anthracis) 		5 / 12 VAL A 254
ALA A 257
ALA A 248
THR A   9
ILE A 212
 None
 1.20A 3dl9B-3hijA:
undetectable		 3dl9B-3hijA:
18.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IA4_B_MTXB164_2
(DIHYDROFOLATE
REDUCTASE)		 3hij DIHYDRODIPICOLINATE
SYNTHASE
(Bacillus
anthracis) 		4 / 4 PHE A   4
LYS A   1
ILE A  76
THR A   6
 None
 1.39A 3ia4B-3hijA:
undetectable		 3ia4B-3hijA:
19.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R0L_D_ACTD127_0
(PHOSPHOLIPASE A2 CB)		 3hij DIHYDRODIPICOLINATE
SYNTHASE
(Bacillus
anthracis) 		4 / 5 PHE A 121
ILE A 145
GLY A 116
HIS A 120
 None
 1.32A 3r0lD-3hijA:
undetectable		 3r0lD-3hijA:
15.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M7T_A_SAMA503_0
(BTRN)		 3hij DIHYDRODIPICOLINATE
SYNTHASE
(Bacillus
anthracis) 		5 / 11 HIS A 210
THR A  26
LEU A  61
LEU A  53
SER A  50
 None
 1.03A 4m7tA-3hijA:
2.9		 4m7tA-3hijA:
19.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U9U_A_ACTA1502_0
(NA(+)-TRANSLOCATING
NADH-QUINONE
REDUCTASE SUBUNIT F)		 3hij DIHYDRODIPICOLINATE
SYNTHASE
(Bacillus
anthracis) 		4 / 5 GLY A 166
ALA A 165
GLY A 139
PRO A 138
 None
KPI  A 163 ( 4.9A)
None
None
 0.91A 4u9uA-3hijA:
undetectable		 4u9uA-3hijA:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U9U_B_ACTB1502_0
(NA(+)-TRANSLOCATING
NADH-QUINONE
REDUCTASE SUBUNIT F)		 3hij DIHYDRODIPICOLINATE
SYNTHASE
(Bacillus
anthracis) 		4 / 5 GLY A 166
ALA A 165
GLY A 139
PRO A 138
 None
KPI  A 163 ( 4.9A)
None
None
 0.90A 4u9uB-3hijA:
undetectable		 4u9uB-3hijA:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ECK_D_ILED601_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 3hij DIHYDRODIPICOLINATE
SYNTHASE
(Bacillus
anthracis) 		4 / 6 ALA A 208
VAL A 241
VAL A 261
HIS A 210
 None
 0.93A 5eckD-3hijA:
undetectable		 5eckD-3hijA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIO_B_HFGB802_0
(PROLINE-TRNA
SYNTHETASE CLASS II
AARS (YBAK RNA
BINDING DOMAIN PLUS
TRNA SYNTHETASE))		 3hij DIHYDRODIPICOLINATE
SYNTHASE
(Bacillus
anthracis) 		5 / 12 PHE A  23
PRO A  14
THR A  13
GLU A  49
THR A  54
 None
 1.43A 5xioB-3hijA:
undetectable		 5xioB-3hijA:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YOD_B_BEZB201_0
(NS3 PROTEASE)		 3hij DIHYDRODIPICOLINATE
SYNTHASE
(Bacillus
anthracis) 		4 / 5 HIS A 120
ALA A  86
SER A  87
GLY A  80
 None
 1.22A 5yodB-3hijA:
undetectable		 5yodB-3hijA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YOD_D_BEZD201_0
(NS3 PROTEASE)		 3hij DIHYDRODIPICOLINATE
SYNTHASE
(Bacillus
anthracis) 		4 / 5 HIS A 120
ALA A  86
SER A  87
GLY A  80
 None
 1.15A 5yodD-3hijA:
undetectable		 5yodD-3hijA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DYO_A_LDPA901_0
(EBONY)		 3hij DIHYDRODIPICOLINATE
SYNTHASE
(Bacillus
anthracis) 		4 / 5 VAL A 132
LEU A 104
HIS A 120
THR A  91
 None
 1.13A 6dyoA-3hijA:
undetectable		 6dyoA-3hijA:
15.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EMU_A_SAMA501_0
(TRNA
(GUANINE(9)-/ADENINE
(9)-N1)-METHYLTRANSF
ERASE)		 3hij DIHYDRODIPICOLINATE
SYNTHASE
(Bacillus
anthracis) 		5 / 12 GLY A 188
ILE A 204
THR A 193
ILE A 175
ILE A 162
 KPI  A 163 ( 3.9A)
None
None
None
KPI  A 163 ( 3.7A)
 0.97A 6emuA-3hijA:
2.7		 6emuA-3hijA:
19.47