SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3hin'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_C_FUAC701_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3hin PUTATIVE
3-HYDROXYBUTYRYL-COA
DEHYDRATASE
(Rhodopseudomonas
palustris) 		4 / 4 ALA A 201
VAL A 132
ALA A 112
HIS A  65
 None
 1.03A 1q23A-3hinA:
undetectable		 1q23A-3hinA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_E_FUAE706_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3hin PUTATIVE
3-HYDROXYBUTYRYL-COA
DEHYDRATASE
(Rhodopseudomonas
palustris) 		4 / 4 ALA A 201
VAL A 132
ALA A 112
HIS A  65
 None
 1.03A 1q23F-3hinA:
undetectable		 1q23F-3hinA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_J_FUAJ711_2
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 3hin PUTATIVE
3-HYDROXYBUTYRYL-COA
DEHYDRATASE
(Rhodopseudomonas
palustris) 		4 / 4 ALA A 201
VAL A 132
ALA A 112
HIS A  65
 None
 1.04A 1q23K-3hinA:
undetectable		 1q23K-3hinA:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AVO_A_PAUA314_0
(PANTOTHENATE KINASE)		 3hin PUTATIVE
3-HYDROXYBUTYRYL-COA
DEHYDRATASE
(Rhodopseudomonas
palustris) 		5 / 11 VAL A  62
LEU A  18
HIS A  65
PHE A  71
ILE A 102
 None
 1.28A 3avoA-3hinA:
0.6		 3avoA-3hinA:
23.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CJT_O_SAMO302_0
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 3hin PUTATIVE
3-HYDROXYBUTYRYL-COA
DEHYDRATASE
(Rhodopseudomonas
palustris) 		6 / 12 LEU A 124
GLY A 121
GLY A 119
VAL A 150
LEU A  40
LEU A  44
 None
 1.49A 3cjtO-3hinA:
undetectable		 3cjtO-3hinA:
25.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G1U_C_ADNC438_1
(ADENOSYLHOMOCYSTEINA
SE)		 3hin PUTATIVE
3-HYDROXYBUTYRYL-COA
DEHYDRATASE
(Rhodopseudomonas
palustris) 		5 / 12 LEU A 124
LEU A  18
LEU A  44
GLY A  43
PHE A  99
 None
 1.44A 3g1uC-3hinA:
undetectable		 3g1uC-3hinA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H52_C_486C4_1
(GLUCOCORTICOID
RECEPTOR)		 3hin PUTATIVE
3-HYDROXYBUTYRYL-COA
DEHYDRATASE
(Rhodopseudomonas
palustris) 		5 / 12 GLY A  74
TRP A  95
MET A  45
LEU A  31
PHE A  71
 None
 1.26A 3h52C-3hinA:
undetectable		 3h52C-3hinA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H52_C_486C4_1
(GLUCOCORTICOID
RECEPTOR)		 3hin PUTATIVE
3-HYDROXYBUTYRYL-COA
DEHYDRATASE
(Rhodopseudomonas
palustris) 		5 / 12 GLY A 120
TRP A  95
MET A  45
LEU A  31
PHE A  71
 None
 1.49A 3h52C-3hinA:
undetectable		 3h52C-3hinA:
20.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_H_CHDH103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 3hin PUTATIVE
3-HYDROXYBUTYRYL-COA
DEHYDRATASE
(Rhodopseudomonas
palustris) 		5 / 11 ASN A  41
LEU A  44
LEU A  48
LEU A  31
LEU A 124
 None
 1.23A 4wg0H-3hinA:
undetectable
4wg0I-3hinA:
undetectable
4wg0J-3hinA:
undetectable		 4wg0H-3hinA:
4.42
4wg0I-3hinA:
4.42
4wg0J-3hinA:
4.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_K_CHDK103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 3hin PUTATIVE
3-HYDROXYBUTYRYL-COA
DEHYDRATASE
(Rhodopseudomonas
palustris) 		5 / 11 LEU A 124
LEU A  31
ASN A  41
LEU A  44
LEU A  48
 None
 1.21A 4wg0I-3hinA:
undetectable
4wg0J-3hinA:
undetectable
4wg0K-3hinA:
undetectable		 4wg0I-3hinA:
4.42
4wg0J-3hinA:
4.42
4wg0K-3hinA:
4.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XTA_B_DIFB501_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 3hin PUTATIVE
3-HYDROXYBUTYRYL-COA
DEHYDRATASE
(Rhodopseudomonas
palustris) 		4 / 8 ILE A 102
SER A  72
LEU A  44
ILE A  29
 None
 0.99A 4xtaB-3hinA:
undetectable		 4xtaB-3hinA:
19.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NFP_A_8W5A804_2
(GLUCOCORTICOID
RECEPTOR)		 3hin PUTATIVE
3-HYDROXYBUTYRYL-COA
DEHYDRATASE
(Rhodopseudomonas
palustris) 		4 / 4 LEU A  75
MET A  45
ILE A 118
LEU A 124
 None
 1.31A 5nfpA-3hinA:
undetectable		 5nfpA-3hinA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNG_B_QPSB601_2
(-)		 3hin PUTATIVE
3-HYDROXYBUTYRYL-COA
DEHYDRATASE
(Rhodopseudomonas
palustris) 		5 / 12 GLY A 120
GLY A  74
LEU A  75
HIS A  91
ASN A  41
 None
 1.04A 6gngB-3hinA:
2.5		 6gngB-3hinA:
19.51