SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3hj6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BX4_A_ADNA350_1
(PROTEIN (ADENOSINE
KINASE))		 3hj6 FRUCTOKINASE
(Halothermothrix
orenii) 		5 / 12 ASP A  33
GLY A  54
GLY A  55
ASN A  59
ASP A 275
 None
 0.39A 1bx4A-3hj6A:
28.3		 1bx4A-3hj6A:
23.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BX4_A_ADNA350_1
(PROTEIN (ADENOSINE
KINASE))		 3hj6 FRUCTOKINASE
(Halothermothrix
orenii) 		5 / 12 LEU A 188
GLY A  54
GLY A  55
ASN A  59
ASP A 275
 None
 0.82A 1bx4A-3hj6A:
28.3		 1bx4A-3hj6A:
23.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LII_A_ADNA699_1
(ADENOSINE KINASE)		 3hj6 FRUCTOKINASE
(Halothermothrix
orenii) 		6 / 12 ASP A  33
LEU A 188
GLY A  54
GLY A  55
ASN A  59
ASP A 275
 None
 0.80A 1liiA-3hj6A:
28.8		 1liiA-3hj6A:
26.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LIK_A_ADNA699_1
(ADENOSINE KINASE)		 3hj6 FRUCTOKINASE
(Halothermothrix
orenii) 		6 / 12 ASP A  33
LEU A 188
GLY A  54
GLY A  55
ASN A  59
ASP A 275
 None
 0.81A 1likA-3hj6A:
28.8		 1likA-3hj6A:
26.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C49_A_ADNA1301_1
(SUGAR KINASE MJ0406)		 3hj6 FRUCTOKINASE
(Halothermothrix
orenii) 		5 / 12 ASP A  33
GLY A  54
GLY A  55
ASN A  59
ASP A 275
 None
 0.40A 2c49A-3hj6A:
25.4		 2c49A-3hj6A:
25.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C49_A_ADNA1301_1
(SUGAR KINASE MJ0406)		 3hj6 FRUCTOKINASE
(Halothermothrix
orenii) 		5 / 12 GLY A  54
GLY A  55
ASN A  59
PHE A 153
ASP A 275
 None
 1.07A 2c49A-3hj6A:
25.4		 2c49A-3hj6A:
25.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C49_B_ADNB1301_1
(SUGAR KINASE MJ0406)		 3hj6 FRUCTOKINASE
(Halothermothrix
orenii) 		4 / 7 ASP A  33
GLY A  54
GLY A  55
ASN A  59
 None
 0.29A 2c49B-3hj6A:
25.2		 2c49B-3hj6A:
25.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_2_BO221405_1
(PROTEASOME COMPONENT
PRE3)		 3hj6 FRUCTOKINASE
(Halothermothrix
orenii) 		5 / 11 THR A 109
THR A 108
ALA A 128
SER A  56
GLY A  55
 None
 1.15A 2f162-3hj6A:
undetectable		 2f162-3hj6A:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_N_BO2N1404_1
(PROTEASOME COMPONENT
PRE3)		 3hj6 FRUCTOKINASE
(Halothermothrix
orenii) 		5 / 11 THR A 109
THR A 108
ALA A 128
SER A  56
GLY A  55
 None
 1.13A 2f16N-3hj6A:
undetectable		 2f16N-3hj6A:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_C_SC2C1289_1
(FICOLIN-2)		 3hj6 FRUCTOKINASE
(Halothermothrix
orenii) 		4 / 6 ARG A 185
ASP A  33
SER A  56
GLY A  55
 None
 1.03A 2j2pA-3hj6A:
undetectable
2j2pC-3hj6A:
undetectable		 2j2pA-3hj6A:
21.01
2j2pC-3hj6A:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J2P_F_SC2F1289_1
(FICOLIN-2)		 3hj6 FRUCTOKINASE
(Halothermothrix
orenii) 		4 / 6 ARG A 185
ASP A  33
SER A  56
GLY A  55
 None
 1.00A 2j2pD-3hj6A:
undetectable
2j2pF-3hj6A:
undetectable		 2j2pD-3hj6A:
21.01
2j2pF-3hj6A:
21.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PKK_A_2FAA501_1
(ADENOSINE KINASE)		 3hj6 FRUCTOKINASE
(Halothermothrix
orenii) 		5 / 12 ASP A  33
GLY A  54
GLY A  55
ASN A  59
ASP A 275
 None
 0.44A 2pkkA-3hj6A:
25.3		 2pkkA-3hj6A:
24.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PKM_A_ADNA501_1
(ADENOSINE KINASE)		 3hj6 FRUCTOKINASE
(Halothermothrix
orenii) 		5 / 12 ASP A  33
GLY A  54
GLY A  55
ASN A  59
ASP A 275
 None
 0.45A 2pkmA-3hj6A:
25.2		 2pkmA-3hj6A:
24.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_F_SVRF502_2
(PHOSPHOLIPASE A2)		 3hj6 FRUCTOKINASE
(Halothermothrix
orenii) 		4 / 5 ILE A  60
SER A  56
PRO A  57
PHE A 153
 None
 1.31A 3bjwC-3hj6A:
undetectable		 3bjwC-3hj6A:
17.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_2_BO221405_1
(PROTEASOME COMPONENT
PRE3
PROTEASOME COMPONENT
PUP1)		 3hj6 FRUCTOKINASE
(Halothermothrix
orenii) 		5 / 12 THR A 109
THR A 108
ALA A 128
SER A  56
GLY A  55
 None
 1.13A 3mg02-3hj6A:
undetectable
3mg0V-3hj6A:
undetectable		 3mg02-3hj6A:
23.10
3mg0V-3hj6A:
24.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_N_BO2N1404_1
(PROTEASOME COMPONENT
PRE3)		 3hj6 FRUCTOKINASE
(Halothermothrix
orenii) 		5 / 11 THR A 109
THR A 108
ALA A 128
SER A  56
GLY A  55
 None
 1.12A 3mg0N-3hj6A:
undetectable		 3mg0N-3hj6A:
23.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RGF_A_BAXA465_2
(CYCLIN-DEPENDENT
KINASE 8)		 3hj6 FRUCTOKINASE
(Halothermothrix
orenii) 		4 / 7 LEU A  86
VAL A  32
LEU A  27
ASP A 129
 None
 0.85A 3rgfA-3hj6A:
undetectable		 3rgfA-3hj6A:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UBO_A_ADNA353_1
(ADENOSINE KINASE)		 3hj6 FRUCTOKINASE
(Halothermothrix
orenii) 		6 / 12 ASP A  33
GLY A  54
GLY A  55
SER A  56
ASN A  59
ASP A 275
 None
 0.59A 3uboA-3hj6A:
28.7		 3uboA-3hj6A:
25.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UBO_B_ADNB353_1
(ADENOSINE KINASE)		 3hj6 FRUCTOKINASE
(Halothermothrix
orenii) 		5 / 12 ASP A  33
GLY A  54
GLY A  55
ASN A  59
ASP A 275
 None
 0.42A 3uboB-3hj6A:
28.8		 3uboB-3hj6A:
25.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UQ6_A_ADNA401_1
(ADENOSINE KINASE,
PUTATIVE)		 3hj6 FRUCTOKINASE
(Halothermothrix
orenii) 		5 / 12 ASP A  33
GLY A  54
GLY A  55
ASN A  59
ASP A 275
 None
 0.45A 3uq6A-3hj6A:
29.0		 3uq6A-3hj6A:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UQ6_A_ADNA401_1
(ADENOSINE KINASE,
PUTATIVE)		 3hj6 FRUCTOKINASE
(Halothermothrix
orenii) 		5 / 12 LEU A 188
GLY A  54
GLY A  55
ASN A  59
ASP A 275
 None
 0.79A 3uq6A-3hj6A:
29.0		 3uq6A-3hj6A:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAQ_A_ADNA401_1
(PUTATIVE ADENOSINE
KINASE)		 3hj6 FRUCTOKINASE
(Halothermothrix
orenii) 		5 / 12 ASP A  33
GLY A  54
GLY A  55
ASN A  59
ASP A 275
 None
 0.46A 3vaqA-3hj6A:
29.0		 3vaqA-3hj6A:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAQ_A_ADNA401_1
(PUTATIVE ADENOSINE
KINASE)		 3hj6 FRUCTOKINASE
(Halothermothrix
orenii) 		5 / 12 LEU A 188
GLY A  54
GLY A  55
ASN A  59
ASP A 275
 None
 0.76A 3vaqA-3hj6A:
29.0		 3vaqA-3hj6A:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAS_A_ADNA401_1
(PUTATIVE ADENOSINE
KINASE)		 3hj6 FRUCTOKINASE
(Halothermothrix
orenii) 		5 / 12 ASP A  33
GLY A  54
GLY A  55
ASN A  59
ASP A 275
 None
 0.42A 3vasA-3hj6A:
29.1		 3vasA-3hj6A:
23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAS_A_ADNA401_1
(PUTATIVE ADENOSINE
KINASE)		 3hj6 FRUCTOKINASE
(Halothermothrix
orenii) 		5 / 12 LEU A 188
GLY A  54
GLY A  55
ASN A  59
ASP A 275
 None
 0.77A 3vasA-3hj6A:
29.1		 3vasA-3hj6A:
23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAS_B_ADNB401_1
(PUTATIVE ADENOSINE
KINASE)		 3hj6 FRUCTOKINASE
(Halothermothrix
orenii) 		5 / 12 ASP A  33
GLY A  54
GLY A  55
ASN A  59
ASP A 275
 None
 0.35A 3vasB-3hj6A:
20.6		 3vasB-3hj6A:
23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VAS_B_ADNB401_1
(PUTATIVE ADENOSINE
KINASE)		 3hj6 FRUCTOKINASE
(Halothermothrix
orenii) 		5 / 12 LEU A 188
GLY A  54
GLY A  55
ASN A  59
ASP A 275
 None
 0.75A 3vasB-3hj6A:
20.6		 3vasB-3hj6A:
23.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DC3_A_ADNA401_1
(ADENOSINE KINASE)		 3hj6 FRUCTOKINASE
(Halothermothrix
orenii) 		6 / 12 ASP A  33
LEU A 188
GLY A  54
ASN A  59
VAL A 111
ASP A 275
 None
 1.01A 4dc3A-3hj6A:
28.8		 4dc3A-3hj6A:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DC3_B_2FAB401_1
(ADENOSINE KINASE)		 3hj6 FRUCTOKINASE
(Halothermothrix
orenii) 		6 / 12 ASP A  33
LEU A 188
GLY A  54
GLY A  55
ASN A  59
ASP A 275
 None
 0.78A 4dc3B-3hj6A:
29.1		 4dc3B-3hj6A:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DC3_B_2FAB401_1
(ADENOSINE KINASE)		 3hj6 FRUCTOKINASE
(Halothermothrix
orenii) 		6 / 12 ASP A  33
LEU A 188
GLY A  54
GLY A  55
ASN A  59
VAL A 111
 None
 0.95A 4dc3B-3hj6A:
29.1		 4dc3B-3hj6A:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3A_A_ADNA500_1
(SUGAR KINASE PROTEIN)		 3hj6 FRUCTOKINASE
(Halothermothrix
orenii) 		5 / 12 ASP A  33
GLY A  54
GLY A  55
ASN A  59
ASP A 275
 None
 0.41A 4e3aA-3hj6A:
28.8		 4e3aA-3hj6A:
27.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3A_B_ADNB500_1
(SUGAR KINASE PROTEIN)		 3hj6 FRUCTOKINASE
(Halothermothrix
orenii) 		5 / 12 ASP A  33
GLY A  54
GLY A  55
ASN A  59
ASP A 275
 None
 0.42A 4e3aB-3hj6A:
29.0		 4e3aB-3hj6A:
27.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKS_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3hj6 FRUCTOKINASE
(Halothermothrix
orenii) 		5 / 12 ASP A  33
GLY A  54
GLY A  55
ASN A  59
ASP A 275
 None
 0.41A 4jksA-3hj6A:
29.1		 4jksA-3hj6A:
27.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKS_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3hj6 FRUCTOKINASE
(Halothermothrix
orenii) 		5 / 12 ASP A  33
GLY A  54
GLY A  55
ASN A  59
ASP A 275
 None
 0.41A 4jksB-3hj6A:
29.0		 4jksB-3hj6A:
27.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKU_A_ADNA500_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3hj6 FRUCTOKINASE
(Halothermothrix
orenii) 		5 / 12 ASP A  33
GLY A  54
GLY A  55
ASN A  59
ASP A 275
 None
 0.38A 4jkuA-3hj6A:
29.1		 4jkuA-3hj6A:
27.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKU_B_ADNB500_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3hj6 FRUCTOKINASE
(Halothermothrix
orenii) 		5 / 12 ASP A  33
GLY A  54
GLY A  55
ASN A  59
ASP A 275
 None
 0.39A 4jkuB-3hj6A:
29.1		 4jkuB-3hj6A:
27.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8C_A_ADNA401_1
(SUGAR KINASE)		 3hj6 FRUCTOKINASE
(Halothermothrix
orenii) 		5 / 12 ASP A  33
GLY A  54
GLY A  55
ASN A  59
ASP A 275
 None
 0.40A 4k8cA-3hj6A:
29.0		 4k8cA-3hj6A:
27.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8C_B_ADNB401_1
(SUGAR KINASE)		 3hj6 FRUCTOKINASE
(Halothermothrix
orenii) 		5 / 12 ASP A  33
GLY A  54
GLY A  55
ASN A  59
ASP A 275
 None
 0.40A 4k8cB-3hj6A:
29.0		 4k8cB-3hj6A:
27.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8K_A_ADNA401_1
(SUGAR KINASE)		 3hj6 FRUCTOKINASE
(Halothermothrix
orenii) 		5 / 12 ASP A  33
GLY A  54
GLY A  55
ASN A  59
ASP A 275
 None
 0.41A 4k8kA-3hj6A:
28.9		 4k8kA-3hj6A:
27.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8K_B_ADNB403_1
(SUGAR KINASE)		 3hj6 FRUCTOKINASE
(Halothermothrix
orenii) 		5 / 12 ASP A  33
GLY A  54
GLY A  55
ASN A  59
ASP A 275
 None
 0.40A 4k8kB-3hj6A:
28.9		 4k8kB-3hj6A:
27.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8P_A_ADNA401_1
(SUGAR KINASE)		 3hj6 FRUCTOKINASE
(Halothermothrix
orenii) 		5 / 12 ASP A  33
GLY A  54
GLY A  55
ASN A  59
ASP A 275
 None
 0.42A 4k8pA-3hj6A:
28.9		 4k8pA-3hj6A:
27.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8P_B_ADNB401_1
(SUGAR KINASE)		 3hj6 FRUCTOKINASE
(Halothermothrix
orenii) 		5 / 12 ASP A  33
GLY A  54
GLY A  55
ASN A  59
ASP A 275
 None
 0.41A 4k8pB-3hj6A:
28.9		 4k8pB-3hj6A:
27.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8T_A_ADNA401_1
(SUGAR KINASE)		 3hj6 FRUCTOKINASE
(Halothermothrix
orenii) 		5 / 12 ASP A  33
GLY A  54
GLY A  55
ASN A  59
ASP A 275
 None
 0.44A 4k8tA-3hj6A:
29.0		 4k8tA-3hj6A:
27.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8T_B_ADNB401_1
(SUGAR KINASE)		 3hj6 FRUCTOKINASE
(Halothermothrix
orenii) 		5 / 12 ASP A  33
GLY A  54
GLY A  55
ASN A  59
ASP A 275
 None
 0.42A 4k8tB-3hj6A:
29.0		 4k8tB-3hj6A:
27.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K93_A_ADNA401_1
(SUGAR KINASE)		 3hj6 FRUCTOKINASE
(Halothermothrix
orenii) 		5 / 12 ASP A  33
GLY A  54
GLY A  55
ASN A  59
ASP A 275
 None
 0.41A 4k93A-3hj6A:
29.1		 4k93A-3hj6A:
27.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K93_B_ADNB402_1
(SUGAR KINASE)		 3hj6 FRUCTOKINASE
(Halothermothrix
orenii) 		5 / 12 ASP A  33
GLY A  54
GLY A  55
ASN A  59
ASP A 275
 None
 0.41A 4k93B-3hj6A:
29.0		 4k93B-3hj6A:
27.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9C_A_ADNA401_1
(SUGAR KINASE)		 3hj6 FRUCTOKINASE
(Halothermothrix
orenii) 		5 / 12 ASP A  33
GLY A  54
GLY A  55
ASN A  59
ASP A 275
 None
 0.41A 4k9cA-3hj6A:
29.0		 4k9cA-3hj6A:
27.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9C_B_ADNB401_1
(SUGAR KINASE)		 3hj6 FRUCTOKINASE
(Halothermothrix
orenii) 		5 / 12 ASP A  33
GLY A  54
GLY A  55
ASN A  59
ASP A 275
 None
 0.41A 4k9cB-3hj6A:
29.0		 4k9cB-3hj6A:
27.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9I_A_ADNA401_1
(SUGAR KINASE)		 3hj6 FRUCTOKINASE
(Halothermothrix
orenii) 		5 / 12 ASP A  33
GLY A  54
GLY A  55
ASN A  59
ASP A 275
 None
 0.42A 4k9iA-3hj6A:
29.1		 4k9iA-3hj6A:
27.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K9I_B_ADNB401_1
(SUGAR KINASE)		 3hj6 FRUCTOKINASE
(Halothermothrix
orenii) 		5 / 12 ASP A  33
GLY A  54
GLY A  55
ASN A  59
ASP A 275
 None
 0.42A 4k9iB-3hj6A:
29.1		 4k9iB-3hj6A:
27.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAD_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3hj6 FRUCTOKINASE
(Halothermothrix
orenii) 		5 / 12 ASP A  33
GLY A  54
GLY A  55
ASN A  59
ASP A 275
 None
 0.41A 4kadA-3hj6A:
29.1		 4kadA-3hj6A:
27.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAD_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3hj6 FRUCTOKINASE
(Halothermothrix
orenii) 		5 / 12 ASP A  33
GLY A  54
GLY A  55
ASN A  59
ASP A 275
 None
 0.40A 4kadB-3hj6A:
29.1		 4kadB-3hj6A:
27.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAH_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3hj6 FRUCTOKINASE
(Halothermothrix
orenii) 		5 / 12 ASP A  33
GLY A  54
GLY A  55
ASN A  59
ASP A 275
 None
 0.42A 4kahA-3hj6A:
29.0		 4kahA-3hj6A:
27.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAH_B_ADNB502_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3hj6 FRUCTOKINASE
(Halothermothrix
orenii) 		5 / 12 ASP A  33
GLY A  54
GLY A  55
ASN A  59
ASP A 275
 None
 0.41A 4kahB-3hj6A:
29.0		 4kahB-3hj6A:
27.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAL_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3hj6 FRUCTOKINASE
(Halothermothrix
orenii) 		5 / 12 ASP A  33
GLY A  54
GLY A  55
ASN A  59
ASP A 275
 None
 0.41A 4kalA-3hj6A:
29.1		 4kalA-3hj6A:
27.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAL_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3hj6 FRUCTOKINASE
(Halothermothrix
orenii) 		5 / 12 ASP A  33
GLY A  54
GLY A  55
ASN A  59
ASP A 275
 None
 0.41A 4kalB-3hj6A:
29.1		 4kalB-3hj6A:
27.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAN_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3hj6 FRUCTOKINASE
(Halothermothrix
orenii) 		5 / 12 ASP A  33
GLY A  54
GLY A  55
ASN A  59
ASP A 275
 None
 0.40A 4kanA-3hj6A:
29.1		 4kanA-3hj6A:
27.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAN_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3hj6 FRUCTOKINASE
(Halothermothrix
orenii) 		5 / 12 ASP A  33
GLY A  54
GLY A  55
ASN A  59
ASP A 275
 None
 0.41A 4kanB-3hj6A:
29.0		 4kanB-3hj6A:
27.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KBE_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3hj6 FRUCTOKINASE
(Halothermothrix
orenii) 		5 / 12 ASP A  33
GLY A  54
GLY A  55
ASN A  59
ASP A 275
 None
 0.42A 4kbeA-3hj6A:
29.0		 4kbeA-3hj6A:
27.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KBE_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3hj6 FRUCTOKINASE
(Halothermothrix
orenii) 		5 / 12 ASP A  33
GLY A  54
GLY A  55
ASN A  59
ASP A 275
 None
 0.42A 4kbeB-3hj6A:
29.0		 4kbeB-3hj6A:
27.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KIC_B_SAMB401_1
(METHYLTRANSFERASE
MPPJ)		 3hj6 FRUCTOKINASE
(Halothermothrix
orenii) 		3 / 3 ARG A 161
ASP A 129
ASP A 103
 None
 0.82A 4kicB-3hj6A:
undetectable		 4kicB-3hj6A:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3hj6 FRUCTOKINASE
(Halothermothrix
orenii) 		5 / 12 ASP A  33
GLY A  54
GLY A  55
ASN A  59
ASP A 275
 None
 0.41A 4lbgA-3hj6A:
29.0		 4lbgA-3hj6A:
27.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBG_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3hj6 FRUCTOKINASE
(Halothermothrix
orenii) 		5 / 12 ASP A  33
GLY A  54
GLY A  55
ASN A  59
ASP A 275
 None
 0.41A 4lbgB-3hj6A:
29.0		 4lbgB-3hj6A:
27.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBX_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3hj6 FRUCTOKINASE
(Halothermothrix
orenii) 		5 / 12 ASP A  33
GLY A  54
GLY A  55
ASN A  59
ASP A 275
 None
 0.41A 4lbxA-3hj6A:
29.0		 4lbxA-3hj6A:
27.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LBX_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3hj6 FRUCTOKINASE
(Halothermothrix
orenii) 		5 / 12 ASP A  33
GLY A  54
GLY A  55
ASN A  59
ASP A 275
 None
 0.43A 4lbxB-3hj6A:
29.0		 4lbxB-3hj6A:
27.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LC4_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3hj6 FRUCTOKINASE
(Halothermothrix
orenii) 		5 / 12 ASP A  33
GLY A  54
GLY A  55
ASN A  59
ASP A 275
 None
 0.41A 4lc4A-3hj6A:
29.0		 4lc4A-3hj6A:
27.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LC4_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3hj6 FRUCTOKINASE
(Halothermothrix
orenii) 		5 / 12 ASP A  33
GLY A  54
GLY A  55
ASN A  59
ASP A 275
 None
 0.42A 4lc4B-3hj6A:
28.9		 4lc4B-3hj6A:
27.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LCA_A_ADNA401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3hj6 FRUCTOKINASE
(Halothermothrix
orenii) 		5 / 12 ASP A  33
GLY A  54
GLY A  55
ASN A  59
ASP A 275
 None
 0.41A 4lcaA-3hj6A:
29.0		 4lcaA-3hj6A:
27.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LCA_B_ADNB401_1
(PROBABLE SUGAR
KINASE PROTEIN)		 3hj6 FRUCTOKINASE
(Halothermothrix
orenii) 		5 / 12 ASP A  33
GLY A  54
GLY A  55
ASN A  59
ASP A 275
 None
 0.40A 4lcaB-3hj6A:
29.0		 4lcaB-3hj6A:
27.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LRH_B_FOLB301_1
(FOLATE RECEPTOR
ALPHA)		 3hj6 FRUCTOKINASE
(Halothermothrix
orenii) 		3 / 3 ASP A 129
TRP A 122
SER A 156
 None
 0.88A 4lrhB-3hj6A:
undetectable		 4lrhB-3hj6A:
18.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LRH_F_FOLF301_1
(FOLATE RECEPTOR
ALPHA)		 3hj6 FRUCTOKINASE
(Halothermothrix
orenii) 		3 / 3 ASP A 129
TRP A 122
SER A 156
 None
 0.93A 4lrhF-3hj6A:
undetectable		 4lrhF-3hj6A:
18.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_A_ADNA401_1
(ADENOSINE KINASE)		 3hj6 FRUCTOKINASE
(Halothermothrix
orenii) 		5 / 12 ASP A  33
LEU A 188
GLY A  55
ASN A  59
ASP A 275
 None
 0.88A 4n09A-3hj6A:
28.1		 4n09A-3hj6A:
24.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_B_ADNB401_1
(ADENOSINE KINASE)		 3hj6 FRUCTOKINASE
(Halothermothrix
orenii) 		6 / 12 ASP A  33
LEU A 188
GLY A  54
GLY A  55
ASN A  59
ASP A 275
 None
 0.80A 4n09B-3hj6A:
28.2		 4n09B-3hj6A:
24.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_C_ADNC401_1
(ADENOSINE KINASE)		 3hj6 FRUCTOKINASE
(Halothermothrix
orenii) 		6 / 12 ASP A  33
LEU A 188
GLY A  54
GLY A  55
ASN A  59
ASP A 275
 None
 0.81A 4n09C-3hj6A:
28.2		 4n09C-3hj6A:
24.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_D_ADND401_1
(ADENOSINE KINASE)		 3hj6 FRUCTOKINASE
(Halothermothrix
orenii) 		6 / 12 ASP A  33
LEU A 188
GLY A  54
GLY A  55
ASN A  59
ASP A 275
 None
 0.80A 4n09D-3hj6A:
28.3		 4n09D-3hj6A:
24.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UBE_A_2FAA401_1
(ADENOSINE KINASE)		 3hj6 FRUCTOKINASE
(Halothermothrix
orenii) 		5 / 12 ASP A  33
GLY A  54
GLY A  55
ASN A  59
ASP A 275
 None
 0.45A 4ubeA-3hj6A:
25.2		 4ubeA-3hj6A:
24.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WOZ_B_MN9B401_0
(N-ACETYLNEURAMINATE
LYASE)		 3hj6 FRUCTOKINASE
(Halothermothrix
orenii) 		4 / 6 SER A 212
LEU A 213
ASP A 214
LEU A 242
 None
 0.91A 4wozA-3hj6A:
undetectable
4wozB-3hj6A:
undetectable		 4wozA-3hj6A:
24.59
4wozB-3hj6A:
24.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XP6_A_B40A601_1
(TRANSPORTER)		 3hj6 FRUCTOKINASE
(Halothermothrix
orenii) 		4 / 5 VAL A 111
ASP A  33
PHE A 153
GLY A  55
 None
 1.20A 4xp6A-3hj6A:
undetectable		 4xp6A-3hj6A:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZB_C_ACTC401_0
(PROTON-GATED ION
CHANNEL)		 3hj6 FRUCTOKINASE
(Halothermothrix
orenii) 		4 / 7 ILE A 282
PHE A 281
VAL A 147
ILE A 177
 None
 0.90A 4zzbC-3hj6A:
undetectable
4zzbD-3hj6A:
undetectable		 4zzbC-3hj6A:
21.04
4zzbD-3hj6A:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KB5_A_ADNA401_1
(ADENOSINE KINASE)		 3hj6 FRUCTOKINASE
(Halothermothrix
orenii) 		5 / 12 ASP A  33
GLY A  54
GLY A  55
ASN A  59
ASP A 275
 None
 0.49A 5kb5A-3hj6A:
28.0		 5kb5A-3hj6A:
24.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KB5_A_ADNA401_1
(ADENOSINE KINASE)		 3hj6 FRUCTOKINASE
(Halothermothrix
orenii) 		5 / 12 LEU A 188
GLY A  54
GLY A  55
ASN A  59
ASP A 275
 None
 0.85A 5kb5A-3hj6A:
28.0		 5kb5A-3hj6A:
24.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KBW_B_RBFB201_1
(RIBOFLAVIN
TRANSPORTER RIBU)		 3hj6 FRUCTOKINASE
(Halothermothrix
orenii) 		5 / 12 LEU A  67
ASP A 287
GLY A 284
ALA A 276
ASN A 299
 None
 1.25A 5kbwB-3hj6A:
undetectable		 5kbwB-3hj6A:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KBW_B_RBFB201_1
(RIBOFLAVIN
TRANSPORTER RIBU)		 3hj6 FRUCTOKINASE
(Halothermothrix
orenii) 		5 / 12 LEU A  67
GLY A 284
ALA A 276
ASN A 299
ASN A  63
 None
 1.38A 5kbwB-3hj6A:
undetectable		 5kbwB-3hj6A:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KC4_E_RBFE201_1
(RIBOFLAVIN
TRANSPORTER RIBU)		 3hj6 FRUCTOKINASE
(Halothermothrix
orenii) 		5 / 12 LEU A  67
GLY A 284
ALA A 276
ASN A 299
ASN A  63
 None
 1.40A 5kc4E-3hj6A:
undetectable		 5kc4E-3hj6A:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_B_6V8B304_0
(PROTEASOME SUBUNIT
BETA TYPE-6
PROTEASOME SUBUNIT
BETA TYPE-7)		 3hj6 FRUCTOKINASE
(Halothermothrix
orenii) 		5 / 12 THR A 109
THR A 108
ALA A 128
SER A  56
GLY A  55
 None
 1.15A 5lf7V-3hj6A:
undetectable
5lf7b-3hj6A:
undetectable		 5lf7V-3hj6A:
21.22
5lf7b-3hj6A:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_N_6V8N305_0
(PROTEASOME SUBUNIT
BETA TYPE-6
PROTEASOME SUBUNIT
BETA TYPE-7)		 3hj6 FRUCTOKINASE
(Halothermothrix
orenii) 		5 / 12 THR A 109
THR A 108
ALA A 128
SER A  56
GLY A  55
 None
 1.15A 5lf7H-3hj6A:
undetectable
5lf7N-3hj6A:
undetectable		 5lf7H-3hj6A:
21.22
5lf7N-3hj6A:
22.56