SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3hj7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z9H_A_IMNA379_1
(MEMBRANE-ASSOCIATED
PROSTAGLANDIN E
SYNTHASE-2)		 3hj7 TRNA(ILE)-LYSIDINE
SYNTHASE
(Geobacillus
kaustophilus) 		5 / 12 PRO A 377
PRO A 364
VAL A 343
SER A 357
LEU A 341
 None
 1.01A 1z9hA-3hj7A:
undetectable		 1z9hA-3hj7A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z9H_B_IMNB381_1
(MEMBRANE-ASSOCIATED
PROSTAGLANDIN E
SYNTHASE-2)		 3hj7 TRNA(ILE)-LYSIDINE
SYNTHASE
(Geobacillus
kaustophilus) 		5 / 12 PRO A 377
PRO A 364
VAL A 343
SER A 357
LEU A 341
 None
 0.99A 1z9hB-3hj7A:
undetectable		 1z9hB-3hj7A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z9H_C_IMNC379_1
(MEMBRANE-ASSOCIATED
PROSTAGLANDIN E
SYNTHASE-2)		 3hj7 TRNA(ILE)-LYSIDINE
SYNTHASE
(Geobacillus
kaustophilus) 		5 / 12 PRO A 377
PRO A 364
VAL A 343
SER A 357
LEU A 341
 None
 1.00A 1z9hC-3hj7A:
undetectable		 1z9hC-3hj7A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z9H_D_IMND476_1
(MEMBRANE-ASSOCIATED
PROSTAGLANDIN E
SYNTHASE-2)		 3hj7 TRNA(ILE)-LYSIDINE
SYNTHASE
(Geobacillus
kaustophilus) 		5 / 12 PRO A 377
PRO A 364
VAL A 343
SER A 357
LEU A 341
 None
 1.01A 1z9hD-3hj7A:
undetectable		 1z9hD-3hj7A:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_A_HCYA1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 3hj7 TRNA(ILE)-LYSIDINE
SYNTHASE
(Geobacillus
kaustophilus) 		5 / 12 ALA A 429
VAL A 380
PHE A 359
ILE A 455
SER A 357
 None
 1.31A 4c49A-3hj7A:
undetectable		 4c49A-3hj7A:
16.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CU6_A_ACTA403_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 3hj7 TRNA(ILE)-LYSIDINE
SYNTHASE
(Geobacillus
kaustophilus) 		4 / 6 VAL A 374
ASP A 376
PRO A 377
ALA A 446
 None
None
None
CL  A   1 (-4.1A)
 0.71A 5cu6A-3hj7A:
undetectable		 5cu6A-3hj7A:
16.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OSP_A_ACTA403_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 3hj7 TRNA(ILE)-LYSIDINE
SYNTHASE
(Geobacillus
kaustophilus) 		4 / 7 VAL A 374
ASP A 376
PRO A 377
ALA A 446
 None
None
None
CL  A   1 (-4.1A)
 0.72A 5ospA-3hj7A:
undetectable		 5ospA-3hj7A:
16.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OSR_A_ACTA402_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 3hj7 TRNA(ILE)-LYSIDINE
SYNTHASE
(Geobacillus
kaustophilus) 		4 / 7 VAL A 374
ASP A 376
PRO A 377
ALA A 446
 None
None
None
CL  A   1 (-4.1A)
 0.74A 5osrA-3hj7A:
undetectable		 5osrA-3hj7A:
16.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OTR_A_ACTA402_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 3hj7 TRNA(ILE)-LYSIDINE
SYNTHASE
(Geobacillus
kaustophilus) 		4 / 5 VAL A 374
ASP A 376
PRO A 377
ALA A 446
 None
None
None
CL  A   1 (-4.1A)
 0.71A 5otrA-3hj7A:
undetectable		 5otrA-3hj7A:
16.08