SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '3hj9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FO4_A_SALA3005_1
(XANTHINE
DEHYDROGENASE)		 3hj9 OXIDOREDUCTASE
(Cupriavidus
pinatubonensis) 		5 / 9 SER A  86
ARG A  82
THR A  91
VAL A  92
ALA A  72
 None
 1.43A 1fo4A-3hj9A:
undetectable		 1fo4A-3hj9A:
10.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HRK_B_CHDB2501_0
(FERROCHELATASE)		 3hj9 OXIDOREDUCTASE
(Cupriavidus
pinatubonensis) 		5 / 12 LEU A  64
LEU A  30
ILE A 210
PRO A 108
VAL A  95
 None
 1.44A 1hrkB-3hj9A:
undetectable		 1hrkB-3hj9A:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RLB_F_REAF177_1
(RETINOL BINDING
PROTEIN)		 3hj9 OXIDOREDUCTASE
(Cupriavidus
pinatubonensis) 		5 / 11 LEU A 138
ALA A  71
VAL A  97
LEU A  99
LEU A  64
 None
 0.85A 1rlbF-3hj9A:
undetectable		 1rlbF-3hj9A:
20.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AX7_B_SALB1336_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 3hj9 OXIDOREDUCTASE
(Cupriavidus
pinatubonensis) 		5 / 9 SER A  86
ARG A  82
THR A  91
VAL A  92
ALA A  72
 None
 1.45A 3ax7B-3hj9A:
0.5		 3ax7B-3hj9A:
10.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3I5U_B_SAMB401_0
(O-METHYLTRANSFERASE)		 3hj9 OXIDOREDUCTASE
(Cupriavidus
pinatubonensis) 		5 / 12 GLY A 180
GLY A 211
PRO A 135
SER A 215
ALA A 177
 None
 1.10A 3i5uB-3hj9A:
undetectable		 3i5uB-3hj9A:
25.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UNC_A_SALA1338_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 3hj9 OXIDOREDUCTASE
(Cupriavidus
pinatubonensis) 		5 / 9 SER A  86
ARG A  82
THR A  91
VAL A  92
ALA A  72
 None
 1.44A 3uncA-3hj9A:
undetectable		 3uncA-3hj9A:
10.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UNC_B_SALB1338_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 3hj9 OXIDOREDUCTASE
(Cupriavidus
pinatubonensis) 		5 / 9 SER A  86
ARG A  82
THR A  91
VAL A  92
ALA A  72
 None
 1.42A 3uncB-3hj9A:
undetectable		 3uncB-3hj9A:
10.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UNI_B_SALB1345_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 3hj9 OXIDOREDUCTASE
(Cupriavidus
pinatubonensis) 		4 / 8 LEU A 113
VAL A  95
LEU A 138
ALA A  98
 None
 0.92A 3uniB-3hj9A:
undetectable		 3uniB-3hj9A:
10.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W1W_B_CHDB504_0
(FERROCHELATASE,
MITOCHONDRIAL)		 3hj9 OXIDOREDUCTASE
(Cupriavidus
pinatubonensis) 		5 / 12 LEU A  64
LEU A  30
ILE A 210
GLN A 208
VAL A  95
 None
 1.25A 3w1wB-3hj9A:
undetectable		 3w1wB-3hj9A:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FLC_C_RAPC999_1
(SERINE/THREONINE-PRO
TEIN KINASE MTOR
FKBP)		 3hj9 OXIDOREDUCTASE
(Cupriavidus
pinatubonensis) 		4 / 8 GLU A 156
SER A 159
GLY A 164
THR A  91
 None
 0.85A 5flcB-3hj9A:
undetectable		 5flcB-3hj9A:
11.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FLC_G_RAPG999_1
(SERINE/THREONINE-PRO
TEIN KINASE MTOR
FKBP)		 3hj9 OXIDOREDUCTASE
(Cupriavidus
pinatubonensis) 		4 / 8 GLU A 156
SER A 159
GLY A 164
THR A  91
 None
 0.85A 5flcF-3hj9A:
undetectable		 5flcF-3hj9A:
11.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_A_SAMA902_1
(MRNA CAPPING ENZYME
P5)		 3hj9 OXIDOREDUCTASE
(Cupriavidus
pinatubonensis) 		3 / 3 TYR A 106
ASP A  94
ASP A 107
 None
 0.85A 5x6yA-3hj9A:
undetectable		 5x6yA-3hj9A:
13.80